Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD/cglD   Type   Machinery gene
Locus tag   NBW44_RS00155 Genome accession   NZ_OW724079
Coordinates   15992..16426 (+) Length   144 a.a.
NCBI ID   WP_284345849.1    Uniprot ID   -
Organism   Streptococcus sp. Marseille-Q3533     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 6379..38997 15992..16426 within 0


Gene organization within MGE regions


Location: 6379..38997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBW44_RS00090 - 6379..7512 (-) 1134 WP_250306706.1 site-specific integrase -
  NBW44_RS00095 - 7516..7710 (-) 195 WP_000598356.1 DUF3173 domain-containing protein -
  NBW44_RS00100 - 7770..8156 (-) 387 WP_001096844.1 hypothetical protein -
  NBW44_RS00105 - 8159..9355 (-) 1197 WP_250306707.1 replication initiation factor domain-containing protein -
  NBW44_RS00110 - 9396..9869 (-) 474 WP_000182279.1 hypothetical protein -
  NBW44_RS00115 - 10189..10635 (+) 447 WP_000287814.1 helix-turn-helix transcriptional regulator -
  NBW44_RS00120 - 10799..11125 (-) 327 WP_049518302.1 multidrug efflux SMR transporter -
  NBW44_RS00125 - 11298..11696 (+) 399 WP_049496811.1 hypothetical protein -
  NBW44_RS00130 nagA 12050..13201 (+) 1152 WP_250306708.1 N-acetylglucosamine-6-phosphate deacetylase -
  NBW44_RS00135 - 13368..13733 (+) 366 WP_142558567.1 DUF1033 family protein -
  NBW44_RS00140 comGA/cglA/cilD 13800..14741 (+) 942 WP_250306709.1 competence type IV pilus ATPase ComGA Machinery gene
  NBW44_RS00145 comGB/cglB 14662..15705 (+) 1044 WP_250306710.1 competence type IV pilus assembly protein ComGB Machinery gene
  NBW44_RS00150 comGC/cglC 15706..16029 (+) 324 WP_250306711.1 competence type IV pilus major pilin ComGC Machinery gene
  NBW44_RS00155 comGD/cglD 15992..16426 (+) 435 WP_284345849.1 competence type IV pilus minor pilin ComGD Machinery gene
  NBW44_RS00160 comGE/cglE 16389..16691 (+) 303 WP_250306712.1 competence type IV pilus minor pilin ComGE Machinery gene
  NBW44_RS00165 comGF/cglF 16654..17115 (+) 462 WP_016466888.1 competence type IV pilus minor pilin ComGF Machinery gene
  NBW44_RS00170 comGG 17093..17530 (+) 438 WP_250306713.1 competence type IV pilus minor pilin ComGG -
  NBW44_RS00175 - 17589..18290 (+) 702 WP_250306714.1 histidine phosphatase family protein -
  NBW44_RS00180 - 18480..20186 (+) 1707 WP_250306715.1 ABC transporter ATP-binding protein -
  NBW44_RS00185 - 20188..21954 (+) 1767 WP_250306716.1 ABC transporter ATP-binding protein -
  NBW44_RS00190 - 22090..22779 (+) 690 WP_250306717.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  NBW44_RS00195 - 22958..24307 (+) 1350 WP_006155372.1 glucose-6-phosphate isomerase -
  NBW44_RS00200 gltX 24437..25897 (+) 1461 WP_250306718.1 glutamate--tRNA ligase -
  NBW44_RS00205 - 26377..27591 (+) 1215 WP_250306719.1 pyridoxal phosphate-dependent aminotransferase -
  NBW44_RS00210 rpmH 27736..27870 (+) 135 WP_000831905.1 50S ribosomal protein L34 -
  NBW44_RS00215 - 28053..29897 (-) 1845 WP_250306720.1 APC family permease -
  NBW44_RS00220 - 30053..30829 (+) 777 WP_250306721.1 TatD family hydrolase -
  NBW44_RS00225 rnmV 30826..31389 (+) 564 WP_250306722.1 ribonuclease M5 -
  NBW44_RS00230 - 31551..32942 (+) 1392 WP_250306723.1 SseB family protein -
  NBW44_RS00235 - 33031..33744 (+) 714 WP_250306724.1 dimethyladenosine transferase -
  NBW44_RS00240 rsmA 33764..34636 (+) 873 WP_250306725.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  NBW44_RS00245 rsgA 34638..35516 (+) 879 WP_250306726.1 ribosome small subunit-dependent GTPase A -
  NBW44_RS00250 rpe 35527..36183 (+) 657 WP_049529734.1 ribulose-phosphate 3-epimerase -
  NBW44_RS00255 - 36146..36808 (+) 663 WP_250306727.1 thiamine diphosphokinase -
  NBW44_RS00260 - 36810..38066 (+) 1257 WP_250306728.1 DNA recombination protein RmuC -
  NBW44_RS00265 - 38056..38997 (+) 942 WP_250306729.1 3'-5' exoribonuclease YhaM family protein -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16336.84 Da        Isoelectric Point: 10.2217

>NTDB_id=1152565 NBW44_RS00155 WP_284345849.1 15992..16426(+) (comGD/cglD) [Streptococcus sp. Marseille-Q3533]
MPSKIRVSQLQIRAFTMLESLLVLGIVSLLALGLSSSVQSTFAAVEEQIFFMEFEELYRETQKRSLASQQKINLMLEETS
IENGYQKLAIPKGIQLQSNQSITFDRAGGNSSLASVRFRTRKEVVRYQLYLGNGKIKRIQETNN

Nucleotide


Download         Length: 435 bp        

>NTDB_id=1152565 NBW44_RS00155 WP_284345849.1 15992..16426(+) (comGD/cglD) [Streptococcus sp. Marseille-Q3533]
ATGCCAAGCAAAATAAGAGTCAGTCAGTTGCAGATTAGGGCCTTTACCATGCTAGAAAGTTTATTGGTCTTAGGAATAGT
CAGCCTGTTAGCCTTGGGCTTGTCGAGTTCAGTTCAATCAACTTTTGCAGCTGTGGAAGAGCAAATTTTCTTTATGGAGT
TTGAGGAACTTTATCGAGAAACCCAGAAGCGAAGTCTGGCTAGTCAGCAGAAAATCAACTTAATGCTAGAAGAGACAAGT
ATTGAGAATGGCTATCAGAAATTAGCCATCCCTAAAGGCATTCAATTGCAGTCCAATCAGTCAATCACCTTTGATAGGGC
TGGAGGGAATTCCTCTCTAGCCAGTGTCCGATTTCGCACAAGGAAAGAAGTGGTTCGCTACCAATTATATTTAGGAAATG
GAAAAATTAAACGCATTCAGGAAACAAACAATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus mitis NCTC 12261

76.389

100

0.764
  comGD/cglD Streptococcus mitis SK321

78.195

92.361

0.722
  comGD/cglD Streptococcus pneumoniae Rx1

78.195

92.361

0.722
  comGD/cglD Streptococcus pneumoniae D39

78.195

92.361

0.722
  comGD/cglD Streptococcus pneumoniae R6

78.195

92.361

0.722
  comGD/cglD Streptococcus pneumoniae TIGR4

77.444

92.361

0.715
  comYD Streptococcus gordonii str. Challis substr. CH1

55.224

93.056

0.514
  comYD Streptococcus mutans UA159

48.092

90.972

0.438
  comYD Streptococcus mutans UA140

48.092

90.972

0.438

Multiple sequence alignment