Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   N7O26_RS00050 Genome accession   NZ_OV996158
Coordinates   6772..8076 (-) Length   434 a.a.
NCBI ID   WP_066025889.1    Uniprot ID   A0A1I4L3Q4
Organism   Enterococcus mundtii strain P2005     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1772..13076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N7O26_RS00020 - 2265..3184 (-) 920 Protein_3 glycosyltransferase family 2 protein -
  N7O26_RS00025 - 3323..3673 (-) 351 WP_019724280.1 PepSY domain-containing protein -
  N7O26_RS00030 pepA 3874..4953 (+) 1080 WP_019724279.1 glutamyl aminopeptidase -
  N7O26_RS00035 - 5077..5397 (+) 321 WP_260697267.1 thioredoxin family protein -
  N7O26_RS00040 - 5419..5873 (+) 455 Protein_7 universal stress protein -
  N7O26_RS00045 ytpR 6120..6725 (+) 606 WP_071866223.1 YtpR family tRNA-binding protein -
  N7O26_RS00050 htrA 6772..8076 (-) 1305 WP_066025889.1 S1C family serine protease Regulator
  N7O26_RS00055 rlmH 8504..8983 (+) 480 WP_034689953.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  N7O26_RS00060 - 9068..9564 (+) 497 Protein_11 DUF1456 family protein -
  N7O26_RS00065 - 9664..10299 (+) 636 WP_010728617.1 hypothetical protein -
  N7O26_RS00070 - 10750..11687 (+) 938 Protein_13 2-dehydropantoate 2-reductase -
  N7O26_RS00075 - 11700..12752 (+) 1053 WP_002291912.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 45124.02 Da        Isoelectric Point: 4.4469

>NTDB_id=1152151 N7O26_RS00050 WP_066025889.1 6772..8076(-) (htrA) [Enterococcus mundtii strain P2005]
MDRRDVTPKMKKRKSNGIWRKLGLGVVGGVIGGLLTFGIFYAATGGGNSVTTSSSSGTQNASGETVVENVKVNVDSDITS
AVDKVQGAVVSVINLQKQSSSSDPFGSLFGQQQESSGEDGELQAYSEGSGVIYKKEGDSAYIVTNNHVVDGQQGLEVLLK
DGTKVKAELVGTDAYTDLAVLKISADKVDTVASFGDSASLKVGEPAIAIGSPLGSQYANSVTSGIVSSLNRQVTSTNESN
ETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSDSSSVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALG
ITMTDLSAVSTQQQEQILKLPSSVTNGVIIRSVQPATPAEKAGLEQYDVITKIDDTEVSSGVELQSVLYGKKVGDTVKIT
YYRGEEEKTVDIKLTIDNTALNQGNSNSSNGSNN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=1152151 N7O26_RS00050 WP_066025889.1 6772..8076(-) (htrA) [Enterococcus mundtii strain P2005]
ATGGACAGAAGAGATGTGACACCAAAAATGAAAAAAAGAAAATCTAATGGCATTTGGCGAAAGCTAGGTCTTGGCGTAGT
TGGTGGCGTGATTGGCGGATTACTGACTTTCGGTATTTTTTATGCAGCAACTGGAGGTGGTAACTCAGTAACGACTTCTT
CTAGCAGTGGGACACAAAATGCATCAGGCGAAACAGTTGTCGAAAATGTAAAAGTCAATGTAGATTCAGATATCACTTCT
GCAGTAGATAAAGTGCAAGGAGCAGTTGTTTCTGTTATCAACCTACAAAAACAAAGTTCATCATCTGACCCGTTTGGTTC
ATTATTTGGCCAACAACAAGAAAGTAGTGGCGAAGATGGCGAATTGCAAGCTTACAGTGAAGGTAGCGGTGTGATTTATA
AAAAAGAGGGCGATTCCGCTTATATCGTGACGAATAATCACGTTGTCGATGGACAACAAGGACTAGAAGTTTTACTAAAA
GATGGAACAAAAGTGAAAGCAGAATTAGTCGGTACAGATGCTTATACTGATTTAGCTGTTTTAAAAATCAGTGCTGACAA
AGTCGATACTGTTGCTTCATTTGGCGACTCTGCTTCATTGAAAGTCGGCGAACCTGCGATTGCGATTGGTTCTCCTCTAG
GTTCTCAATACGCAAACTCGGTGACATCAGGAATTGTTTCTTCCTTGAATCGTCAAGTGACAAGTACAAATGAATCTAAT
GAGACAGTGAATATCAATGCTATCCAAACAGATGCAGCGATCAACCCAGGGAACTCTGGTGGTCCACTAGTTAATATCGA
AGGCCAAGTTATTGGTATCAATTCAAGTAAAATTGCATCGACTTCTGATTCTTCAAGTGTAAGTGTTGAAGGAATGGGCT
TTGCGATTCCAAGTAATGATGTCGTAAATATCATCAATCAACTTGAAAAAGATGGAAAAGTAACACGCCCTGCACTGGGT
ATCACAATGACCGATCTTTCCGCCGTTTCTACACAACAACAGGAACAGATCTTGAAATTACCATCTTCTGTAACAAATGG
CGTGATCATTCGTTCGGTTCAACCAGCAACGCCTGCGGAAAAAGCTGGCTTAGAACAATATGATGTCATCACAAAAATCG
ATGATACAGAAGTCTCATCTGGTGTTGAATTACAGTCTGTGCTTTATGGTAAAAAAGTTGGTGACACTGTGAAGATCACT
TATTACCGTGGCGAAGAAGAAAAAACTGTAGATATCAAATTGACAATTGATAATACTGCATTAAATCAAGGAAATTCAAA
TAGTTCCAATGGCTCAAATAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(13-416)

Trypsin-like peptidase domain (Trypsin_2)

(128-273)

PDZ domain (PDZ_2)

(317-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4L3Q4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.522

90.092

0.509
  htrA Streptococcus gordonii str. Challis substr. CH1

53.598

92.857

0.498
  htrA Streptococcus mitis NCTC 12261

53.03

91.244

0.484
  htrA Streptococcus pneumoniae Rx1

58.929

77.419

0.456
  htrA Streptococcus pneumoniae D39

58.929

77.419

0.456
  htrA Streptococcus pneumoniae R6

58.929

77.419

0.456
  htrA Streptococcus pneumoniae TIGR4

58.929

77.419

0.456

Multiple sequence alignment