Detailed information NTG1152131

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: MMH06_RS10385
• Genome accession: NZ_OV904788
• Coordinates: 2026680..2027633 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain RMV7 isolate RMV7domi
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2021680..2032633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MMH06_RS10360	-	2022161..2022256 (-)	96	Protein_2016	IS630 family transposase	-
MMH06_RS10365 (IONPJBJN_02066)	-	2022669..2023010 (+)	342	Protein_2017	IS3 family transposase	-
MMH06_RS10370 (IONPJBJN_02067)	prsA	2023127..2024068 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
MMH06_RS10375 (IONPJBJN_02068)	-	2024135..2024848 (-)	714	WP_000230400.1	O-methyltransferase	-
MMH06_RS10380 (IONPJBJN_02069)	pepF	2024850..2026661 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
MMH06_RS10385 (IONPJBJN_02070)	coiA	2026680..2027633 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
MMH06_RS10390 (IONPJBJN_02071)	tehB	2027706..2028566 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
MMH06_RS10395 (IONPJBJN_02072)	smpB	2028582..2029049 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
MMH06_RS10400 (IONPJBJN_02073)	rnr	2029012..2031366 (-)	2355	WP_000654886.1	ribonuclease R	-
MMH06_RS10405 (IONPJBJN_02074)	secG	2031468..2031701 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
MMH06_RS10410	rpmG	2031741..2031890 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=1152131 MMH06_RS10385 WP_000495909.1 2026680..2027633(-) (coiA) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1152131 MMH06_RS10385 WP_000495909.1 2026680..2027633(-) (coiA) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435