Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   MMH06_RS10380 Genome accession   NZ_OV904788
Coordinates   2024850..2026661 (-) Length   603 a.a.
NCBI ID   WP_000244158.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain RMV7 isolate RMV7domi     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2019850..2031661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MMH06_RS10345 (IONPJBJN_02062) - 2019964..2020806 (+) 843 WP_000954117.1 DUF368 domain-containing protein -
  MMH06_RS10350 (IONPJBJN_02063) - 2020806..2021288 (+) 483 WP_001085888.1 aminoacyl-tRNA deacylase -
  MMH06_RS10355 (IONPJBJN_02064) - 2021288..2021908 (+) 621 WP_000780813.1 histidine phosphatase family protein -
  MMH06_RS10360 - 2022161..2022256 (-) 96 Protein_2016 IS630 family transposase -
  MMH06_RS10365 (IONPJBJN_02066) - 2022669..2023010 (+) 342 Protein_2017 IS3 family transposase -
  MMH06_RS10370 (IONPJBJN_02067) prsA 2023127..2024068 (-) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  MMH06_RS10375 (IONPJBJN_02068) - 2024135..2024848 (-) 714 WP_000230400.1 O-methyltransferase -
  MMH06_RS10380 (IONPJBJN_02069) pepF 2024850..2026661 (-) 1812 WP_000244158.1 oligoendopeptidase F Regulator
  MMH06_RS10385 (IONPJBJN_02070) coiA 2026680..2027633 (-) 954 WP_000495909.1 competence protein CoiA Machinery gene
  MMH06_RS10390 (IONPJBJN_02071) tehB 2027706..2028566 (-) 861 WP_000413757.1 SAM-dependent methyltransferase TehB -
  MMH06_RS10395 (IONPJBJN_02072) smpB 2028582..2029049 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -
  MMH06_RS10400 (IONPJBJN_02073) rnr 2029012..2031366 (-) 2355 WP_000654886.1 ribonuclease R -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 70294.21 Da        Isoelectric Point: 4.5513

>NTDB_id=1152130 MMH06_RS10380 WP_000244158.1 2024850..2026661(-) (pepF) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
MVLQRNERNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHM
KNDQDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELL
AGAGEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNV
KVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQE
ALKKAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYT
RETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLT
SDFLNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSD
YPLNVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=1152130 MMH06_RS10380 WP_000244158.1 2024850..2026661(-) (pepF) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
ATGGTATTACAAAGAAATGAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCA
GGCTTGGGAAGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTG
CGGATAACCTACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTATGCTCATATG
AAGAATGACCAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCA
AGCCTTTTCATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGC
TGCAGGTTTATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTG
GCTGGAGCTGGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGT
CCTAGACGATGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTC
GCCGTGGTGCCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTT
AAGGTGCAAAATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGA
AAGTGTTTATGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAA
TCTTGGGGATTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAATTTTACCTACCAAGAA
GCCTTGAAAAAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTCAAACGTGCCTTCAGCGAGCG
TTGGATTGATGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGC
TTCTCAACTGGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACT
CGTGAAACTCAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTT
GACGGAGAAATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTG
GAACAGTTTTCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACA
AGCGATTTCCTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCA
ATACGAGTGGGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAG
CCTTGGCTGAAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGAC
TATCCACTTAATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGA
ACGCCGTTTAAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(115-184)

Peptidase family M3 (Peptidase_M3)

(205-584)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.34

98.507

0.663

Multiple sequence alignment