Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   KJA93_RS11885 Genome accession   NZ_OD940431
Coordinates   2489276..2490574 (+) Length   432 a.a.
NCBI ID   WP_126254770.1    Uniprot ID   -
Organism   Enterococcus faecalis isolate TM6294     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2484276..2495574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJA93_RS14145 (TM6294_02428) - 2484436..2486430 (+) 1995 WP_227264201.1 AAA family ATPase -
  KJA93_RS11875 (TM6294_02429) - 2486414..2488210 (+) 1797 WP_085454828.1 nuclease domain-containing protein -
  KJA93_RS11880 (TM6294_02430) rlmH 2488396..2488875 (-) 480 WP_126254771.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KJA93_RS11885 (TM6294_02431) htrA 2489276..2490574 (+) 1299 WP_126254770.1 trypsin-like peptidase domain-containing protein Regulator
  KJA93_RS11890 (TM6294_02432) ytpR 2490621..2491241 (-) 621 WP_025193822.1 YtpR family tRNA-binding protein -
  KJA93_RS11895 (TM6294_02433) - 2491452..2491907 (-) 456 WP_002385249.1 universal stress protein -
  KJA93_RS11900 (TM6294_02434) - 2492055..2492369 (-) 315 WP_002355015.1 thioredoxin family protein -
  KJA93_RS11905 (TM6294_02435) pepA 2492381..2493457 (-) 1077 WP_002355013.1 glutamyl aminopeptidase -
  KJA93_RS11910 (TM6294_02436) - 2493764..2494105 (+) 342 WP_002355012.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44847.95 Da        Isoelectric Point: 4.9968

>NTDB_id=1150663 KJA93_RS11885 WP_126254770.1 2489276..2490574(+) (htrA) [Enterococcus faecalis isolate TM6294]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNSATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1150663 KJA93_RS11885 WP_126254770.1 2489276..2490574(+) (htrA) [Enterococcus faecalis isolate TM6294]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATTCGGCGACGA
CGACATCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACGCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTGTCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCGATTG
GTTCCCCTCTAGGCTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATTAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

PDZ domain (PDZ_2)

(319-416)

Peptidase family M50 (Peptidase_M50)

(9-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.806

88.426

0.502
  htrA Streptococcus gordonii str. Challis substr. CH1

53.202

93.981

0.5
  htrA Streptococcus mitis NCTC 12261

55.135

85.648

0.472
  htrA Streptococcus pneumoniae TIGR4

55.807

81.713

0.456
  htrA Streptococcus pneumoniae Rx1

55.807

81.713

0.456
  htrA Streptococcus pneumoniae D39

55.807

81.713

0.456
  htrA Streptococcus pneumoniae R6

55.807

81.713

0.456

Multiple sequence alignment