Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   CKV85_RS09005 Genome accession   NZ_LT906454
Coordinates   1846950..1848845 (-) Length   631 a.a.
NCBI ID   WP_095123401.1    Uniprot ID   -
Organism   Streptococcus acidominimus strain NCTC11291     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1841950..1853845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV85_RS08980 (SAMEA4504048_01919) - 1842661..1843023 (-) 363 WP_029691591.1 S1 RNA-binding domain-containing protein -
  CKV85_RS08985 (SAMEA4504048_01920) - 1843023..1844420 (-) 1398 WP_095123393.1 Cof-type HAD-IIB family hydrolase -
  CKV85_RS08990 (SAMEA4504048_01921) - 1844463..1845104 (-) 642 WP_095123395.1 response regulator transcription factor -
  CKV85_RS08995 (SAMEA4504048_01922) - 1845097..1846095 (-) 999 WP_095123398.1 sensor histidine kinase -
  CKV85_RS09000 (SAMEA4504048_01923) liaF 1846092..1846790 (-) 699 WP_095123399.1 cell wall-active antibiotics response protein LiaF -
  CKV85_RS09005 (SAMEA4504048_01924) pknB 1846950..1848845 (-) 1896 WP_095123401.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CKV85_RS09010 (SAMEA4504048_01925) - 1848845..1849582 (-) 738 WP_017769981.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  CKV85_RS09015 (SAMEA4504048_01926) rsmB 1849631..1850953 (-) 1323 WP_095123402.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CKV85_RS09020 (SAMEA4504048_01927) fmt 1850946..1851878 (-) 933 WP_095123404.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68218.48 Da        Isoelectric Point: 4.6052

>NTDB_id=1147502 CKV85_RS09005 WP_095123401.1 1846950..1848845(-) (pknB) [Streptococcus acidominimus strain NCTC11291]
MIQIGKLFAGRYRILKSIGRGGMADVYLAHDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLAMEYVNGPDLKKYIQDHAPLSNQETIRIMSEVLSAMQLAHQKGIVHRDLKPQNVLLTKDGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTCHIPFDGDSAVTIALQHFQKPLPSIIFENRNVP
QSLENVVIKATAKKLTDRYTSTTEMYQDLITTLHPRRAREAKLVFQDTTDTKTLPKIEPAPAKEPPKPSVVADSTPLPQN
DKLEKSVAANTQPPKKAKRPWWQRLFRLLLLLVVIVAAGLAYFMMSSSNDSVVVPDVSGQSIREAQSTLEDSGLVVGSVI
RQESSQVDEGDVIATNPKAGTTAKEGSEVDLTVSSGTDTFVMTDYTGMSYEDAVKDLIENYNLREKQIVKKEVASNSTEP
GQIISQTPEAGDTFNPSGDGEIVFEVATASSVTMPALVGYSYADAKNALLELGFKSSQIQADSDQASSSAIVYAQYPYAG
TVMELAANDTITLYLSTTSDSSSTTSSEPASSSDSTGSTASSSSSSTSDSEHSDSEIPDSTGTSTEATSGS

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=1147502 CKV85_RS09005 WP_095123401.1 1846950..1848845(-) (pknB) [Streptococcus acidominimus strain NCTC11291]
ATGATCCAAATCGGCAAACTATTTGCTGGGCGCTATCGCATATTAAAATCCATCGGGCGTGGTGGGATGGCAGATGTCTA
TCTGGCTCATGATTTGATTTTGGACAATGAAGAAGTGGCTATAAAAGTCCTTCGCACCAATTATCAGACTGATCAGATTG
CGGTTGCACGTTTCCAAAGAGAAGCGCGAGCAATGGCAGAGTTAAGTCATCCCAATATTGTTGCCATTCGCGATATTGGC
GAGGAAGATGGGCAGCAGTTTCTGGCTATGGAGTATGTTAATGGCCCAGACTTAAAGAAATATATCCAAGACCATGCTCC
CCTATCGAATCAAGAGACGATTCGTATCATGAGTGAAGTGCTCTCAGCGATGCAATTGGCGCACCAAAAGGGAATTGTGC
ATCGCGATTTGAAACCTCAGAATGTGCTTCTGACAAAAGATGGTGTCGCGAAAGTGACAGATTTTGGGATAGCAGTGGCC
TTTGCAGAGACCAGTCTCACTCAGACCAATTCGATGCTGGGAAGTGTGCATTACCTATCTCCGGAGCAAGCGCGTGGCTC
AAAAGCAACTGTTCAGAGTGATATTTATGCTATGGGAATCATGTTGTTTGAAATGTTAACGTGTCATATCCCGTTTGATG
GAGATAGTGCGGTGACGATTGCTCTGCAACATTTTCAAAAACCGCTTCCTTCGATTATCTTTGAAAATCGTAATGTGCCA
CAATCTTTAGAAAATGTTGTGATCAAGGCAACTGCCAAGAAATTAACTGATCGTTACACCTCAACGACAGAAATGTATCA
GGATTTGATTACGACATTGCATCCTAGAAGAGCTCGTGAAGCAAAATTGGTCTTTCAAGATACTACAGATACCAAAACAC
TTCCGAAGATAGAGCCTGCACCAGCAAAAGAGCCTCCTAAACCGAGTGTTGTTGCAGATTCAACGCCCCTACCTCAAAAT
GATAAGTTAGAGAAGTCAGTTGCGGCAAATACACAACCTCCTAAAAAAGCGAAGCGTCCGTGGTGGCAGCGACTATTTAG
ATTATTACTCTTGCTTGTCGTTATTGTCGCTGCGGGATTAGCTTACTTTATGATGTCGAGTAGCAATGACTCTGTAGTGG
TTCCAGATGTTTCTGGTCAAAGTATTCGAGAAGCTCAAAGCACCCTTGAGGATTCTGGTCTGGTTGTTGGTTCGGTCATC
AGACAGGAAAGCTCGCAAGTAGATGAGGGTGATGTTATTGCTACCAATCCAAAAGCTGGAACAACAGCAAAAGAAGGTAG
TGAAGTTGACTTAACAGTTTCAAGTGGTACAGACACTTTTGTCATGACAGATTATACTGGAATGAGTTATGAGGATGCTG
TTAAGGACCTAATAGAGAATTACAATCTTCGAGAAAAGCAAATTGTGAAAAAAGAAGTGGCAAGTAATAGTACCGAACCA
GGACAGATTATTAGCCAAACACCAGAAGCAGGTGATACTTTTAATCCTTCTGGAGATGGTGAAATCGTATTTGAAGTGGC
CACGGCTTCTAGTGTAACCATGCCAGCCTTAGTAGGCTATAGTTATGCGGATGCTAAAAATGCCCTATTAGAGCTTGGTT
TTAAATCGTCGCAAATTCAAGCAGATTCAGATCAAGCGTCTTCGTCAGCTATTGTCTATGCACAATACCCATACGCTGGT
ACGGTCATGGAGTTGGCTGCAAATGACACGATAACGCTGTATTTAAGTACCACCTCTGACAGTAGTTCGACAACCTCTTC
TGAACCAGCTTCTAGCAGTGACAGTACTGGTTCAACAGCATCAAGTTCATCAAGTAGCACTTCTGATTCAGAGCACTCAG
ATTCAGAAATACCAGATAGCACGGGGACATCAACCGAAGCTACTTCAGGAAGTTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-507)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(512-577)

Protein kinase domain (Pkinase)

(12-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

63.077

92.71

0.585
  stkP/pknB Streptococcus salivarius strain HSISS4

62.755

93.185

0.585
  stkP Streptococcus pneumoniae TIGR4

53.806

91.601

0.493
  stkP Streptococcus pneumoniae D39

53.633

91.601

0.491
  stkP Streptococcus pneumoniae R6

53.633

91.601

0.491
  stkP Streptococcus pneumoniae Rx1

53.46

91.601

0.49

Multiple sequence alignment