Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   CKV83_RS04420 Genome accession   NZ_LT906439
Coordinates   952890..953594 (-) Length   234 a.a.
NCBI ID   WP_018372786.1    Uniprot ID   -
Organism   Streptococcus merionis strain NCTC13788     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 947890..958594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV83_RS04405 (SAMEA4412692_00881) rnc 949624..950319 (-) 696 WP_018372783.1 ribonuclease III -
  CKV83_RS04410 (SAMEA4412692_00882) vicX 950722..951525 (-) 804 WP_018372784.1 MBL fold metallo-hydrolase Regulator
  CKV83_RS04415 (SAMEA4412692_00883) micB 951512..952897 (-) 1386 WP_018372785.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CKV83_RS04420 (SAMEA4412692_00884) micA 952890..953594 (-) 705 WP_018372786.1 response regulator YycF Regulator
  CKV83_RS11400 (SAMEA4412692_00885) - 953692..953844 (-) 153 WP_018372787.1 hypothetical protein -
  CKV83_RS04425 (SAMEA4412692_00887) - 954597..955316 (-) 720 WP_018372789.1 hypothetical protein -
  CKV83_RS04430 (SAMEA4412692_00888) - 955664..956707 (-) 1044 WP_018372790.1 D-alanine--D-alanine ligase -
  CKV83_RS04435 (SAMEA4412692_00889) recR 957052..957648 (-) 597 WP_018372791.1 recombination mediator RecR -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26923.85 Da        Isoelectric Point: 4.8937

>NTDB_id=1147130 CKV83_RS04420 WP_018372786.1 952890..953594(-) (micA) [Streptococcus merionis strain NCTC13788]
MKKILVVDDEKPISDIIKFNMTREGYEVVTAFDGREALAQFEAEKPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELSEQVPEADSKQISEIIVGELQILPDAFLVRKNGRDLELT
HREFELVHHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDVPSRPEYILTRRGVGYYIRTND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1147130 CKV83_RS04420 WP_018372786.1 952890..953594(-) (micA) [Streptococcus merionis strain NCTC13788]
ATGAAAAAAATCTTAGTCGTTGACGATGAAAAACCAATTTCAGATATTATAAAATTTAACATGACTCGCGAGGGTTATGA
AGTCGTGACGGCCTTTGATGGTCGCGAAGCTTTGGCGCAGTTTGAAGCTGAAAAGCCTGATATTCTTATTTTAGATTTGA
TGCTGCCAGAGTTGGATGGCCTTGAGGTGGCTCGCACGATTCGAAAGACGAGCAATGTGCCTATCATTGTGCTATCTGCT
AAAGACAGTGAGTTTGATAAGGTCATCGGTCTTGAAATCGGCGCAGATGACTATGTTACCAAACCATTTTCAAATAGGGA
GTTACAAGCACGTGTGAAAGCGTTGTTGCGCCGTAGCGAACTCTCTGAGCAGGTGCCAGAAGCAGATAGCAAGCAGATCT
CTGAAATCATAGTGGGAGAATTGCAAATCTTGCCAGATGCCTTTTTGGTCCGTAAAAATGGGAGAGATTTAGAATTAACG
CACCGTGAGTTTGAATTGGTGCATCACTTAGCGACTCACATGGGACAAGTTATGACTAGAGAACATTTGCTTGAGACCGT
TTGGGGGTATGATTATTTTGGTGATGTCCGCACAGTTGATGTGACGGTTCGTCGTCTCCGCGAGAAAATTGAAGATGTAC
CAAGCCGCCCTGAGTATATCCTAACACGACGTGGCGTTGGTTATTACATAAGAACGAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.769

100

0.808
  vicR Streptococcus mutans UA159

78.298

100

0.786
  covR Streptococcus salivarius strain HSISS4

43.043

98.291

0.423
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.174

98.291

0.415

Multiple sequence alignment