Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CKV83_RS02840 Genome accession   NZ_LT906439
Coordinates   611039..611713 (+) Length   224 a.a.
NCBI ID   WP_026216979.1    Uniprot ID   A0A239SPP9
Organism   Streptococcus merionis strain NCTC13788     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 606039..616713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV83_RS02815 (SAMEA4412692_00565) manA 606239..607183 (-) 945 WP_018373551.1 mannose-6-phosphate isomerase, class I -
  CKV83_RS11685 (SAMEA4412692_00566) - 607363..607890 (-) 528 WP_095114559.1 transposase -
  CKV83_RS11690 (SAMEA4412692_00567) - 607880..608206 (-) 327 WP_095114560.1 IS630 transposase-related protein -
  CKV83_RS02830 (SAMEA4412692_00568) - 608333..609466 (-) 1134 WP_018373907.1 ABC transporter ATP-binding protein -
  CKV83_RS02835 (SAMEA4412692_00569) - 609621..610487 (-) 867 WP_018373908.1 helix-turn-helix domain-containing protein -
  CKV83_RS02840 (SAMEA4412692_00570) ciaR 611039..611713 (+) 675 WP_026216979.1 response regulator transcription factor Regulator
  CKV83_RS02845 (SAMEA4412692_00571) ciaH 611790..613046 (+) 1257 WP_408640773.1 sensor histidine kinase Regulator
  CKV83_RS02855 (SAMEA4412692_00573) - 614767..615204 (+) 438 WP_018374559.1 hypothetical protein -
  CKV83_RS02865 pgk 615500..615655 (+) 156 Protein_564 phosphoglycerate kinase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25525.28 Da        Isoelectric Point: 4.3963

>NTDB_id=1147125 CKV83_RS02840 WP_026216979.1 611039..611713(+) (ciaR) [Streptococcus merionis strain NCTC13788]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAESGVYDLILLDLMLPEKDGFTVLRELRQKGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFSENSLVYGDVTVNLATNEVRVADHEVEFLGKEFDLLVY
FLQNQNVILPKNQIFDRIWGFDSDTTVSVVEVYVSKIRKKLKGTQFVKNLSTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1147125 CKV83_RS02840 WP_026216979.1 611039..611713(+) (ciaR) [Streptococcus merionis strain NCTC13788]
ATGATTAAAATATTATTAGTGGAAGATGATTTAAGTTTATCCAATTCAGTGTTTGACTTTCTAGATGATTTTGCAGATGT
CATGCAAGTGTTTGATGGCGAAGAAGGCATTTATGAGGCAGAATCGGGAGTTTATGATCTCATTTTGCTAGATTTAATGT
TACCTGAAAAAGACGGCTTTACCGTTCTTCGCGAACTGCGTCAAAAAGGGATCACAACGCCAGTTCTCATCATGACAGCT
AAAGAATCCCTTGATGATAAAGGTCATGGTTTTGAACTTGGTGCCGATGATTACTTGACCAAGCCATTTTATCTAGAAGA
GTTAAAAATGCGTATTCAGGCACTCTTAAAACGCTCAGGAAAGTTTTCTGAAAATAGTCTAGTTTATGGTGATGTCACAG
TAAATCTTGCGACAAATGAAGTTAGAGTAGCTGATCACGAAGTCGAATTTTTGGGTAAGGAATTTGATTTGCTTGTTTAT
TTTCTACAGAATCAAAACGTTATTTTACCGAAAAATCAGATTTTTGACCGCATTTGGGGCTTTGACAGTGACACAACAGT
CTCTGTTGTAGAGGTTTACGTTTCTAAAATTCGTAAAAAGTTAAAAGGTACTCAATTTGTTAAAAACTTGTCAACACTCA
GAAGCGTGGGATATATTTTAAAAAATGCAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239SPP9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

86.996

99.554

0.866
  ciaR Streptococcus pneumoniae Rx1

86.161

100

0.862
  ciaR Streptococcus pneumoniae D39

86.161

100

0.862
  ciaR Streptococcus pneumoniae R6

86.161

100

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.161

100

0.862
  vicR Streptococcus mutans UA159

34.615

100

0.362

Multiple sequence alignment