Detailed information NTG1147126

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: CKV83_RS02845
• Genome accession: NZ_LT906439
• Coordinates: 611790..613046 (+)
• Length: 418 a.a.
• NCBI ID: WP_408640773.1
• Uniprot ID: -
• Organism: Streptococcus merionis strain NCTC13788
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 606790..618046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV83_RS11685 (SAMEA4412692_00566)	-	607363..607890 (-)	528	WP_095114559.1	transposase	-
CKV83_RS11690 (SAMEA4412692_00567)	-	607880..608206 (-)	327	WP_095114560.1	IS630 transposase-related protein	-
CKV83_RS02830 (SAMEA4412692_00568)	-	608333..609466 (-)	1134	WP_018373907.1	ABC transporter ATP-binding protein	-
CKV83_RS02835 (SAMEA4412692_00569)	-	609621..610487 (-)	867	WP_018373908.1	helix-turn-helix domain-containing protein	-
CKV83_RS02840 (SAMEA4412692_00570)	ciaR	611039..611713 (+)	675	WP_026216979.1	response regulator transcription factor	Regulator
CKV83_RS02845 (SAMEA4412692_00571)	ciaH	611790..613046 (+)	1257	WP_408640773.1	sensor histidine kinase	Regulator
CKV83_RS02855 (SAMEA4412692_00573)	-	614767..615204 (+)	438	WP_018374559.1	hypothetical protein	-
CKV83_RS02865	pgk	615500..615655 (+)	156	Protein_564	phosphoglycerate kinase	-

Sequence

Protein

• Length: 418 a.a.
• Molecular weight: 47245.21 Da
• Isoelectric Point: 5.1226

>NTDB_id=1147126 CKV83_RS02845 WP_408640773.1 611790..613046(+) (ciaH) [Streptococcus merionis strain NCTC13788]
MTLIILNIINVSAYSEVDSRLNQLASSPEKIITTASSRAVFGDDLTYEVFTERVADSSDALINNGDHKPIAKFGYNANTS
ALVFDKNKKLIFEADPFLQLDQIDFDFNNLGKLLETEIVNASGDTEVFRFVVVRVPDEISESVEYAVALTNITQLKALNS
SNNKIIVLIMLSFWLLSIFASYWLTIITIKPIKEMLEKQKAFVENASHELRTPLAVLQNRLESLFRKPDTTILDEIESIA
SSLDEVRNMRLLTSNLLNLARRDGELKVVLQVVEPEFFDTAFNNFSLIADENQKQFKSQNLVRKTIQTDSALLKQVMTII
FDNAVKYTGEDGEIKITSKIRERQLVVSIEDNGLGISDENKKKIFDRFYRVDKARTRQNGGFGLGLSLAKQIVDQLKGQI
LVHDRVPKGTIFELRLPI

Nucleotide

• Length: 1257 bp

>NTDB_id=1147126 CKV83_RS02845 WP_408640773.1 611790..613046(+) (ciaH) [Streptococcus merionis strain NCTC13788]
ATGACTCTGATTATTTTAAATATTATCAATGTCAGCGCATATAGTGAGGTGGATAGTAGGCTAAATCAACTAGCGAGTTC
ACCAGAAAAAATTATTACTACCGCCAGTTCAAGAGCCGTTTTCGGGGATGATTTAACCTATGAAGTTTTTACAGAGCGAG
TAGCTGACAGTAGCGACGCATTGATTAATAATGGTGATCATAAGCCTATTGCAAAATTTGGTTACAATGCGAATACAAGT
GCGCTTGTCTTTGATAAAAATAAAAAGCTTATTTTTGAGGCAGATCCTTTTTTGCAGCTAGACCAGATTGATTTCGATTT
TAATAATTTAGGAAAGCTGTTAGAAACTGAAATTGTCAATGCCAGTGGTGATACTGAGGTATTTAGATTTGTTGTTGTTC
GAGTTCCGGACGAGATAAGCGAGTCTGTTGAATATGCAGTCGCTTTAACCAACATTACCCAGCTCAAGGCCTTAAATTCC
AGCAACAATAAAATTATCGTTCTTATTATGCTTTCTTTTTGGCTCTTATCCATTTTTGCTTCCTATTGGTTAACTATCAT
TACAATAAAACCGATTAAGGAAATGCTCGAAAAGCAAAAAGCCTTTGTAGAAAATGCTAGTCACGAACTGCGAACACCTT
TAGCCGTTCTCCAAAATCGATTAGAATCCTTGTTCAGAAAGCCAGATACAACTATTTTGGACGAGATCGAATCGATTGCT
TCTAGTTTGGATGAAGTGAGAAATATGCGATTGTTGACATCAAATCTTCTTAATCTTGCTAGAAGAGATGGGGAGTTAAA
AGTTGTGCTCCAAGTTGTTGAACCTGAATTTTTTGATACTGCTTTTAATAATTTTTCGCTCATTGCAGACGAAAATCAGA
AGCAATTTAAATCTCAAAATTTAGTCAGGAAAACTATTCAAACAGATAGCGCTCTACTGAAGCAGGTGATGACAATCATA
TTTGATAATGCTGTTAAGTATACTGGTGAAGATGGTGAAATAAAAATAACGTCAAAAATTAGAGAAAGACAATTAGTGGT
TAGCATTGAAGACAATGGCTTGGGGATTTCCGATGAAAACAAGAAAAAGATATTTGATCGTTTTTATCGGGTGGATAAGG
CTAGAACACGCCAAAATGGGGGCTTTGGCTTGGGATTATCCCTAGCAAAACAAATTGTTGATCAATTAAAAGGTCAAATT
TTGGTGCACGACCGTGTTCCGAAAGGAACAATCTTTGAACTTCGATTACCGATATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (200-264)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (309-417)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	49.76	99.522	0.495
ciaH	Streptococcus pneumoniae Rx1	49.165	100	0.493
ciaH	Streptococcus pneumoniae D39	49.165	100	0.493
ciaH	Streptococcus pneumoniae R6	49.165	100	0.493
ciaH	Streptococcus pneumoniae TIGR4	49.165	100	0.493