Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BUC38_RS12560 Genome accession   NZ_LT671674
Coordinates   2559421..2560617 (+) Length   398 a.a.
NCBI ID   WP_044679209.1    Uniprot ID   -
Organism   Streptococcus suis strain LS9N     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2554421..2565617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUC38_RS12530 - 2555080..2557659 (+) 2580 WP_044690316.1 YfhO family protein -
  BUC38_RS12550 - 2558060..2558743 (-) 684 WP_024393106.1 YoaK family protein -
  BUC38_RS12555 rlmH 2558768..2559247 (-) 480 WP_023371894.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  BUC38_RS12560 htrA 2559421..2560617 (+) 1197 WP_044679209.1 trypsin-like peptidase domain-containing protein Regulator
  BUC38_RS12565 spo0J 2560678..2561442 (+) 765 WP_044689234.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 41852.90 Da        Isoelectric Point: 4.5454

>NTDB_id=1146019 BUC38_RS12560 WP_044679209.1 2559421..2560617(+) (htrA) [Streptococcus suis strain LS9N]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSTITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKAGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGETIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=1146019 BUC38_RS12560 WP_044679209.1 2559421..2560617(+) (htrA) [Streptococcus suis strain LS9N]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTCTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCATCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTACTATCACTAGTGTCAGCAATGTTCAATACA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTTGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCTAATACAGTTACTCAAGGTATTATTTCTAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ACGGTCAAACAATCTCAACCAACGCTATTCAAACCGATACAGCTATCAACCCAGGAAACTCTGGAGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCAGGTGTGGCTGTGGAAGG
GATGGGATTCGCTATTCCTGCAAATGATGCCGTAGCCATTATCAATCAACTTGAGAAAGCTGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAACTATTCAAAATAAGAGTGATCTCCAAAGTGCTCTCTACAAACATCAGATTGGAGACACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(103-248)

PDZ domain (PDZ_2)

(293-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

60.453

99.749

0.603
  htrA Streptococcus gordonii str. Challis substr. CH1

60.506

99.246

0.6
  htrA Streptococcus pneumoniae Rx1

57.506

98.744

0.568
  htrA Streptococcus pneumoniae D39

57.506

98.744

0.568
  htrA Streptococcus pneumoniae R6

57.506

98.744

0.568
  htrA Streptococcus pneumoniae TIGR4

57.506

98.744

0.568
  htrA Streptococcus mitis NCTC 12261

57.506

98.744

0.568

Multiple sequence alignment