Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BUC38_RS10630 Genome accession   NZ_LT671674
Coordinates   2179224..2179946 (-) Length   240 a.a.
NCBI ID   WP_029175761.1    Uniprot ID   A0A123TMX7
Organism   Streptococcus suis strain LS9N     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2174224..2184946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUC38_RS10610 sufD 2175340..2176602 (-) 1263 WP_044691246.1 Fe-S cluster assembly protein SufD -
  BUC38_RS10615 sufC 2176619..2177392 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  BUC38_RS10625 - 2178055..2179227 (-) 1173 WP_044691202.1 MraY family glycosyltransferase -
  BUC38_RS10630 mecA 2179224..2179946 (-) 723 WP_029175761.1 adaptor protein MecA Regulator
  BUC38_RS10635 - 2180074..2180913 (-) 840 WP_024377889.1 undecaprenyl-diphosphate phosphatase -
  BUC38_RS10640 - 2181036..2182601 (+) 1566 WP_044691205.1 ABC transporter substrate-binding protein/permease -
  BUC38_RS10645 - 2182594..2183337 (+) 744 WP_024381054.1 amino acid ABC transporter ATP-binding protein -
  BUC38_RS10650 - 2183466..2183675 (-) 210 WP_009910800.1 hypothetical protein -
  BUC38_RS10655 - 2183761..2184663 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28035.58 Da        Isoelectric Point: 4.0497

>NTDB_id=1146014 BUC38_RS10630 WP_029175761.1 2179224..2179946(-) (mecA) [Streptococcus suis strain LS9N]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDFSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEVDEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=1146014 BUC38_RS10630 WP_029175761.1 2179224..2179946(-) (mecA) [Streptococcus suis strain LS9N]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGTGGTATGCTGAGTTTTCGTGTAACTCCGAAGCCAGATCGGGTAGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTTTCGGAACTTGGTGATGTTGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGTAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A123TMX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

49.59

100

0.504
  mecA Streptococcus thermophilus LMD-9

47.917

100

0.479
  mecA Streptococcus thermophilus LMG 18311

47.5

100

0.475

Multiple sequence alignment