Detailed information NTG1145065

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: STACADC2_RS00920
• Genome accession: NZ_LT604076
• Coordinates: 162138..162887 (+)
• Length: 249 a.a.
• NCBI ID: WP_087009637.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ACA-DC
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 157138..167887

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STACADC2_RS09440 (STACADC2_0140)	-	157713..157883 (+)	171	WP_172838670.1	hypothetical protein	-
STACADC2_RS00895 (STACADC2_0141)	-	157970..158077 (+)	108	WP_002949251.1	LPXTG cell wall anchor domain-containing protein	-
STACADC2_RS00900 (STACADC2_0142)	-	158164..158904 (-)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
STACADC2_RS00905 (STACADC2_0143)	-	158904..160454 (-)	1551	WP_011225362.1	ABC transporter substrate-binding protein/permease	-
STACADC2_RS00910 (STACADC2_0144)	-	160657..161511 (+)	855	WP_014607892.1	undecaprenyl-diphosphate phosphatase	-
STACADC2_RS00915	-	161657..161872 (-)	216	WP_011226805.1	DUF3021 family protein	-
STACADC2_RS00920 (STACADC2_0146)	mecA	162138..162887 (+)	750	WP_087009637.1	adaptor protein MecA	Regulator
STACADC2_RS00925 (STACADC2_0147)	-	162891..164048 (+)	1158	WP_002947632.1	glycosyltransferase family 4 protein	-
STACADC2_RS00930 (STACADC2_0148)	sufC	164209..164979 (+)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
STACADC2_RS00935 (STACADC2_0149)	sufD	165016..166278 (+)	1263	WP_002947640.1	Fe-S cluster assembly protein SufD	-
STACADC2_RS00940 (STACADC2_0150)	-	166332..167564 (+)	1233	WP_002949261.1	cysteine desulfurase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29200.77 Da
• Isoelectric Point: 4.0930

>NTDB_id=1145065 STACADC2_RS00920 WP_087009637.1 162138..162887(+) (mecA) [Streptococcus thermophilus strain ACA-DC]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKKVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=1145065 STACADC2_RS00920 WP_087009637.1 162138..162887(+) (mecA) [Streptococcus thermophilus strain ACA-DC]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGAAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAAGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMD-9	99.197	100	0.992
mecA	Streptococcus thermophilus LMG 18311	99.197	100	0.992
mecA	Streptococcus mutans UA159	57.787	97.992	0.566
mecA	Streptococcus pneumoniae Rx1	46.586	100	0.466
mecA	Streptococcus pneumoniae D39	46.586	100	0.466
mecA	Streptococcus pneumoniae R6	46.586	100	0.466
mecA	Streptococcus pneumoniae TIGR4	46.586	100	0.466