Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   BN3853_RS13160 Genome accession   NZ_LT220504
Coordinates   2802396..2804588 (+) Length   730 a.a.
NCBI ID   WP_061713740.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus strain BPL5     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2797396..2809588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BN3853_RS13130 - 2797608..2797907 (+) 300 WP_005692238.1 bacteriocin immunity protein -
  BN3853_RS13140 - 2799375..2799635 (+) 261 WP_014571574.1 hypothetical protein -
  BN3853_RS13145 - 2799755..2800531 (-) 777 WP_005692246.1 response regulator transcription factor -
  BN3853_RS13150 - 2800524..2801837 (-) 1314 WP_019728291.1 GHKL domain-containing protein -
  BN3853_RS13155 - 2802013..2802147 (+) 135 WP_005692249.1 bacteriocin-like peptide, LSEI_2386 family -
  BN3853_RS13160 comA 2802396..2804588 (+) 2193 WP_061713740.1 peptide cleavage/export ABC transporter Regulator
  BN3853_RS13165 - 2804601..2805980 (+) 1380 WP_005692252.1 bacteriocin secretion accessory protein -
  BN3853_RS13170 - 2806041..2806451 (+) 411 WP_005692253.1 hypothetical protein -
  BN3853_RS13175 - 2806631..2807986 (+) 1356 WP_005692255.1 threonine/serine ThrE exporter family protein -
  BN3853_RS13185 - 2808286..2809369 (-) 1084 Protein_2563 aldo/keto reductase -

Sequence

Protein


Download         Length: 730 a.a.        Molecular weight: 81562.78 Da        Isoelectric Point: 7.0674

>NTDB_id=1143636 BN3853_RS13160 WP_061713740.1 2802396..2804588(+) (comA) [Lacticaseibacillus rhamnosus strain BPL5]
MFKHTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSLAHLRELAKTNQDGTTALGIVRAAEALAFETKSVQA
DMQLFDLEDVPYPFIAHVLKRGELLHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKED
KGSLFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGLLVAYLLQAVLTYGQNFLM
AVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFADANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLV
SLIAVPCYLVIVFAFQRPFDRLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKRSFSYTKADQL
QQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKLQMARVANNRLNEVYLVESEFKE
QRHLTERHLIEGPIRVRDVSFKYGFGQDVLKNINLEVPENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPV
KDINLTTLRQYIEYVPQDPFIFSGTVLENLTLGSRSDVSEQDLTQACLAAEIAADIANLPQQWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGKIVEQGDHATLLAQ
DGYYARLVHE

Nucleotide


Download         Length: 2193 bp        

>NTDB_id=1143636 BN3853_RS13160 WP_061713740.1 2802396..2804588(+) (comA) [Lacticaseibacillus rhamnosus strain BPL5]
ATGTTTAAACACACCCCCAAACTAGGCCAGATCACCTACTACAAACGCTTCTACACCGCACAAGTTGACGAGCGTGACTG
TGGTGTGGCTGCGTTAAACATGCTGCTTAAATACAATGGGTCGGACTATTCGTTAGCCCACCTGCGCGAGTTAGCGAAGA
CAAATCAGGATGGCACGACGGCTTTGGGAATCGTTCGGGCCGCTGAAGCACTAGCGTTTGAGACAAAATCGGTACAGGCG
GATATGCAGTTGTTTGATCTTGAGGATGTGCCTTATCCGTTTATTGCCCATGTGCTGAAGCGCGGTGAATTGCTTCATTA
CTATGTTGTTTTTAAAGCAACGCGCACGAGTATTCTGATTGGCGATCCTGACCCGTCAGTGCGCATGACCTGGCTTTCGC
GAGAGGTGTTTGAAAAAGAATGGTCGGGTGTGGCCATCTTTATTGCACCGGCGCCGCAGTATCAGCCGCGTAAGGAGGAC
AAAGGCAGTTTGTTTGCGTTTGTACCCATGCTGGCTAAGCAAAAAGGTATTATCGCGAACATTATTCTGGCCGCGGTATT
GATTACGGTCATTAGTATCGTTGGGTCGTATTTTTTGCAGTCTATTATTGATACGTATATACCGAATGCCATGCGGACGA
CGATGGGGATGATTGCTAGTGGCCTTTTGGTGGCTTACTTGCTGCAAGCTGTGTTGACTTATGGCCAGAATTTTTTGATG
GCGGTGTTGGGGCAGCGGCTTGCGATTGATGTCATTTTAGGGTATGTGCGCCACTTATATGAATTGCCGATGTCGTTTTT
TTCAACTCGGCGGACCGGAGAGATTGTGTCGCGGTTTGCGGATGCCAATAAAATTATTGACGCGCTGGCGAATACGATTA
TGACGTTGTTTTTGGATGTCTGGATTGTCCTAATATTAGGCATTGTTCTAGGGATCCAAAATGGGACTTTGTTTTTAGTG
TCATTGATTGCCGTGCCGTGTTATTTGGTGATTGTTTTTGCATTTCAGCGGCCGTTTGATCGGTTGAACCAAGAGACGAT
GGAAAGTAACGCAATCTTGAGTTCATCGATTATTGAAGATTTGAATGGCATTGAAACCATCAAGTCCTTGACCGGCGAAC
GAGTTAGCTATGAACGGGTTGATCGGGAATTTCTAACCTATTTGAAGAGGTCGTTTAGTTACACCAAGGCAGATCAGTTA
CAGCAAGCGATTAAAGGCCTGTTGAAGCTGGCGTTGAACGTTGTGGTGTTGTGGATTGGGGCAAGTTTGGTGATTGCCAA
TCGAATGAGTTTGGGGCAGATGCTGACCTTTAATGCGCTGCTGTCATACTTTACGAATCCGCTTGAAAGCATCATCAACC
TACAGCCAAAGTTACAAATGGCGCGGGTTGCTAACAATCGCCTGAATGAAGTTTATCTGGTCGAATCGGAATTCAAAGAA
CAGCGGCACTTGACGGAGCGGCATTTAATCGAAGGTCCGATACGCGTTCGGGATGTCTCGTTTAAATATGGTTTTGGCCA
AGATGTGTTAAAAAACATCAACCTTGAAGTGCCGGAAAATGCTAAATATACCATTGTCGGTATGAGCGGTTCTGGTAAGT
CGACATTAGCAAAATTATTAGTTGGCTTTTACCCGGTTGATGCCGATAAAGGAACCATTACGTTTAATGGCATTCCGGTC
AAAGACATTAACCTGACAACATTACGGCAATATATTGAATATGTACCTCAGGATCCGTTTATTTTTTCGGGCACGGTGTT
GGAGAATTTGACGTTAGGTAGCCGTTCGGATGTTTCGGAACAAGATTTGACGCAGGCGTGTTTGGCTGCGGAAATTGCCG
CAGACATCGCAAACTTACCGCAGCAGTGGCAGACCAAATTGTCAGAAAGCGGCAGCATTTTATCAGGCGGTCAGAAGCAG
CGGCTGGCGATTGCACGGGCCTTGTTGTCACCGGCAAAAGTACTGATTTTTGACGAATCGACCAGCAGTCTGGATACCAT
TACAGAGCGAAAAATTGTCGATCGCTTGCTGGCAATGACGGATCGGACCATTATTTTTGTTGCCCATCGCTTAACTATTG
CGGCTAAAACCGAACAAATTGTGGTGATGGATCATGGCAAAATTGTGGAACAAGGTGACCATGCAACGTTGTTAGCCCAA
GACGGTTATTACGCGCGCCTGGTTCATGAGTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(510-662)

ABC transporter transmembrane region (ABC_membrane)

(180-448)

Peptidase C39 family (Peptidase_C39)

(18-152)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae D39

58.322

97.945

0.571
  comA Streptococcus pneumoniae R6

58.322

97.945

0.571
  comA Streptococcus pneumoniae Rx1

58.322

97.945

0.571
  comA Streptococcus pneumoniae TIGR4

57.902

97.945

0.567
  comA Streptococcus mitis NCTC 12261

57.902

97.945

0.567
  comA Streptococcus mitis SK321

57.762

97.945

0.566
  comA Streptococcus gordonii str. Challis substr. CH1

56.745

98.493

0.559
  comA/nlmT Streptococcus mutans UA159

53.964

98.493

0.532

Multiple sequence alignment