Detailed information NTG1143052

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STN4L_RS08135
• Genome accession: NZ_LS974444
• Coordinates: 1528047..1528484 (+)
• Length: 145 a.a.
• NCBI ID: WP_011681686.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain N4L
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1523047..1533484

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STN4L_RS08105 (STN4L_01902)	-	1524721..1525083 (+)	363	WP_014608746.1	DUF1033 family protein	-
STN4L_RS08110 (STN4L_01903)	comGA/cglA/cilD	1525164..1526105 (+)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
STN4L_RS08115 (STN4L_01904)	comYB	1525987..1527087 (+)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
STN4L_RS08120 (STN4L_01905)	comYC	1527084..1527410 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STN4L_RS08125 (STN4L_01906)	comYD	1527370..1527798 (+)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STN4L_RS08130 (STN4L_01907)	comGE	1527770..1528063 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STN4L_RS08135 (STN4L_01908)	comYF	1528047..1528484 (+)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
STN4L_RS08140 (STN4L_01909)	comGG	1528462..1528779 (+)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
STN4L_RS08145 (STN4L_01910)	comYH	1528824..1529780 (+)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
STN4L_RS08150 (STN4L_01911)	-	1529836..1531029 (+)	1194	WP_014608740.1	acetate kinase	-
STN4L_RS08155	-	1531278..1531476 (+)	199	Protein_1510	helix-turn-helix transcriptional regulator	-
STN4L_RS10620 (STN4L_01913)	-	1531488..1531763 (+)	276	WP_011681681.1	hypothetical protein	-
STN4L_RS10625 (STN4L_01914)	-	1531807..1532145 (+)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
STN4L_RS08170 (STN4L_01915)	-	1532219..1532662 (+)	444	WP_113870473.1	CAAX protease	-
STN4L_RS08175 (STN4L_01916)	-	1532759..1533421 (+)	663	WP_011681679.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.85 Da
• Isoelectric Point: 8.4500

>NTDB_id=1143052 STN4L_RS08135 WP_011681686.1 1528047..1528484(+) (comYF) [Streptococcus thermophilus strain N4L]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1143052 STN4L_RS08135 WP_011681686.1 1528047..1528484(+) (comYF) [Streptococcus thermophilus strain N4L]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae Rx1	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae R6	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae TIGR4	49.286	96.552	0.476
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.809	97.241	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434