Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STN4L_RS05635 Genome accession   NZ_LS974444
Coordinates   1081423..1082112 (-) Length   229 a.a.
NCBI ID   WP_084828484.1    Uniprot ID   A0A0E2Q3Q9
Organism   Streptococcus thermophilus strain N4L     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1076423..1087112
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STN4L_RS05615 (STN4L_01307) dnaI 1077229..1078131 (-) 903 WP_084828487.1 primosomal protein DnaI -
  STN4L_RS05620 (STN4L_01308) - 1078135..1079310 (-) 1176 WP_100262514.1 DnaD domain protein -
  STN4L_RS05625 (STN4L_01309) nrdR 1079307..1079786 (-) 480 WP_002949642.1 transcriptional regulator NrdR -
  STN4L_RS05630 (STN4L_01310) covS 1079909..1081426 (-) 1518 WP_084828485.1 HAMP domain-containing histidine kinase Regulator
  STN4L_RS05635 (STN4L_01311) covR 1081423..1082112 (-) 690 WP_084828484.1 response regulator transcription factor Regulator
  STN4L_RS05640 (STN4L_01312) - 1082269..1082805 (-) 537 WP_113870431.1 DUF177 domain-containing protein -
  STN4L_RS05645 (STN4L_01313) rsmG 1083102..1083815 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STN4L_RS05650 (STN4L_01314) - 1083885..1085249 (+) 1365 WP_011680735.1 TrkH family potassium uptake protein -
  STN4L_RS05655 (STN4L_01315) - 1085289..1085960 (+) 672 WP_002946492.1 potassium channel family protein -
  STN4L_RS10510 - 1085977..1086147 (-) 171 Protein_1082 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26683.82 Da        Isoelectric Point: 4.7059

>NTDB_id=1143035 STN4L_RS05635 WP_084828484.1 1081423..1082112(-) (covR) [Streptococcus thermophilus strain N4L]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKVPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1143035 STN4L_RS05635 WP_084828484.1 1081423..1082112(-) (covR) [Streptococcus thermophilus strain N4L]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTGATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGTACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q3Q9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

44.828

100

0.454
  micA Streptococcus pneumoniae Cp1015

42.083

100

0.441

Multiple sequence alignment