Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   STN4L_RS05630 Genome accession   NZ_LS974444
Coordinates   1079909..1081426 (-) Length   505 a.a.
NCBI ID   WP_084828485.1    Uniprot ID   A0A0E2Q5R4
Organism   Streptococcus thermophilus strain N4L     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1074909..1086426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STN4L_RS10040 - 1075080..1075749 (-) 670 Protein_1071 HI_0552 family protein -
  STN4L_RS05610 (STN4L_01306) der 1075813..1077123 (-) 1311 WP_084828488.1 ribosome biogenesis GTPase Der -
  STN4L_RS05615 (STN4L_01307) dnaI 1077229..1078131 (-) 903 WP_084828487.1 primosomal protein DnaI -
  STN4L_RS05620 (STN4L_01308) - 1078135..1079310 (-) 1176 WP_100262514.1 DnaD domain protein -
  STN4L_RS05625 (STN4L_01309) nrdR 1079307..1079786 (-) 480 WP_002949642.1 transcriptional regulator NrdR -
  STN4L_RS05630 (STN4L_01310) covS 1079909..1081426 (-) 1518 WP_084828485.1 HAMP domain-containing histidine kinase Regulator
  STN4L_RS05635 (STN4L_01311) covR 1081423..1082112 (-) 690 WP_084828484.1 response regulator transcription factor Regulator
  STN4L_RS05640 (STN4L_01312) - 1082269..1082805 (-) 537 WP_113870431.1 DUF177 domain-containing protein -
  STN4L_RS05645 (STN4L_01313) rsmG 1083102..1083815 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STN4L_RS05650 (STN4L_01314) - 1083885..1085249 (+) 1365 WP_011680735.1 TrkH family potassium uptake protein -
  STN4L_RS05655 (STN4L_01315) - 1085289..1085960 (+) 672 WP_002946492.1 potassium channel family protein -
  STN4L_RS10510 - 1085977..1086147 (-) 171 Protein_1082 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57568.03 Da        Isoelectric Point: 5.5179

>NTDB_id=1143034 STN4L_RS05630 WP_084828485.1 1079909..1081426(-) (covS) [Streptococcus thermophilus strain N4L]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAAFY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1143034 STN4L_RS05630 WP_084828485.1 1079909..1081426(-) (covS) [Streptococcus thermophilus strain N4L]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCTTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACGCGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q5R4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.223

99.406

0.937

Multiple sequence alignment