Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DQL17_RS02950 Genome accession   NZ_LS483496
Coordinates   584088..585431 (-) Length   447 a.a.
NCBI ID   WP_050948867.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC8455     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 579088..590431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL17_RS02920 (NCTC8455_00577) - 580103..580375 (-) 273 WP_005630954.1 HU family DNA-binding protein -
  DQL17_RS02925 (NCTC8455_00578) - 580514..581104 (-) 591 WP_021034387.1 YjaG family protein -
  DQL17_RS02930 (NCTC8455_00579) nudC 581140..581934 (-) 795 WP_021034386.1 NAD(+) diphosphatase -
  DQL17_RS02935 (NCTC8455_00580) nfuA 582002..582598 (-) 597 WP_021034385.1 Fe-S biogenesis protein NfuA -
  DQL17_RS02940 (NCTC8455_00581) - 582674..583360 (-) 687 WP_050948865.1 ComF family protein -
  DQL17_RS02945 (NCTC8455_00582) tnpA 583636..584091 (-) 456 WP_050948866.1 IS200/IS605 family transposase -
  DQL17_RS02950 (NCTC8455_00583) comE 584088..585431 (-) 1344 WP_050948867.1 type IV pilus secretin PilQ Machinery gene
  DQL17_RS02955 (NCTC8455_00584) comD 585441..585854 (-) 414 WP_050948868.1 pilus assembly protein PilP Machinery gene
  DQL17_RS02960 (NCTC8455_00585) comC 585851..586372 (-) 522 WP_050948869.1 competence protein ComC Machinery gene
  DQL17_RS02965 (NCTC8455_00586) comB 586369..586878 (-) 510 WP_050948870.1 hypothetical protein Machinery gene
  DQL17_RS02970 (NCTC8455_00587) comA 586879..587676 (-) 798 WP_050948871.1 pilus assembly protein PilM Machinery gene
  DQL17_RS02975 (NCTC8455_00588) - 587775..590375 (+) 2601 WP_050948872.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49341.57 Da        Isoelectric Point: 6.8467

>NTDB_id=1142718 DQL17_RS02950 WP_050948867.1 584088..585431(-) (comE) [Haemophilus influenzae strain NCTC8455]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKGQVAGNLTTNEPHLMSHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENAARVAGSLSGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVSYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=1142718 DQL17_RS02950 WP_050948867.1 584088..585431(-) (comE) [Haemophilus influenzae strain NCTC8455]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTCTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCCAAAAC
TGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACATTGGAACAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATGGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAGGCAAAGG
GCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAATGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGACAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTCGTGATTCAAGATGAACCTCGTTCTGTGCAAAATATTAAAAAACTAATTGCTGAAATGGATAAACCTATTGAGCA
GATCGCTATTGAAGCGCGTATTGTGACAATTACGGACGAAAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACGGAAAATGCTGCGCGTGTAGCGGGCAGCTTATCCGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCGATAGCATTACAAGTCGCGAAAATTAATGGTCGATTGCTCGATTTAGAATT
AAGCGCGTTAGAGCGTGAAAATAATGTGGAAATTATCGCAAGCCCTCGCTTACTAACCACAAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTATATTGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGCGAGGCGGTG
CTTGGTTTGGAAGTCACACCACATATTTCTAAAGATAACAATATTTTACTTGATTTATTAGTGAGCCAAAACTCACCAGG
TTCTCGTGTTTCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTGTTTCACGACACAATTACGAAAAGCGAAGATAAGGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTCAGCAAAGAAAGCGAACGACATCAAAAACGTGAGTTAGTGATTTTTGTCACGCCGCATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAGCAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

96.404

99.553

0.96
  comE Haemophilus influenzae Rd KW20

96.18

99.553

0.957
  comE Glaesserella parasuis strain SC1401

52.706

95.078

0.501
  pilQ Vibrio campbellii strain DS40M4

42.959

93.736

0.403
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.17

0.389
  pilQ Vibrio cholerae strain A1552

42.233

92.17

0.389

Multiple sequence alignment