Detailed information NTG1142341

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: DQN71_RS10570
• Genome accession: NZ_LS483471
• Coordinates: 2008348..2008785 (-)
• Length: 145 a.a.
• NCBI ID: WP_015605916.1
• Uniprot ID: -
• Organism: Streptococcus cristatus strain NCTC13807
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2003348..2013785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN71_RS10545 (NCTC13807_02004)	-	2004316..2005203 (+)	888	WP_041826841.1	RluA family pseudouridine synthase	-
DQN71_RS10555 (NCTC13807_02005)	-	2005685..2006878 (-)	1194	WP_111694592.1	acetate kinase	-
DQN71_RS10560 (NCTC13807_02006)	comYH	2006914..2007879 (-)	966	WP_015605914.1	class I SAM-dependent methyltransferase	Machinery gene
DQN71_RS10565 (NCTC13807_02007)	comGG	2007960..2008367 (-)	408	WP_015605915.1	competence type IV pilus minor pilin ComGG	-
DQN71_RS10570 (NCTC13807_02008)	comGF/cglF	2008348..2008785 (-)	438	WP_015605916.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQN71_RS10575 (NCTC13807_02009)	comGE/cglE	2008769..2009038 (-)	270	WP_015605917.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQN71_RS10580 (NCTC13807_02010)	comYD	2009028..2009462 (-)	435	WP_041826842.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQN71_RS10585 (NCTC13807_02011)	comYC	2009422..2009739 (-)	318	WP_015605919.1	competence type IV pilus major pilin ComGC	Machinery gene
DQN71_RS10590 (NCTC13807_02012)	comYB	2009736..2010752 (-)	1017	WP_015605920.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQN71_RS10595 (NCTC13807_02013)	comYA	2010700..2011641 (-)	942	WP_015605921.1	competence type IV pilus ATPase ComGA	Machinery gene
DQN71_RS10600 (NCTC13807_02014)	-	2011726..2012097 (-)	372	WP_015605922.1	DUF1033 family protein	-
DQN71_RS10605 (NCTC13807_02015)	-	2012232..2013500 (-)	1269	WP_041826843.1	CapA family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16945.48 Da
• Isoelectric Point: 9.8258

>NTDB_id=1142341 DQN71_RS10570 WP_015605916.1 2008348..2008785(-) (comGF/cglF) [Streptococcus cristatus strain NCTC13807]
MLKNVKIKAFTLLETLVALLVLSGSMLVFQSLTKLLAFELRQQQENKQQEWLLFVDQLETELSRSQFDRVENDKIYVKQD
GKNIALGKSRSDDFRKTDASGRGYQPMVYGLKAAPITQKGNLVRFRFQFENDLEREYIYRVQDKS

Nucleotide

• Length: 438 bp

>NTDB_id=1142341 DQN71_RS10570 WP_015605916.1 2008348..2008785(-) (comGF/cglF) [Streptococcus cristatus strain NCTC13807]
GTGTTAAAAAACGTTAAAATCAAAGCTTTTACACTTTTAGAAACGCTAGTTGCTCTGCTGGTCTTGAGTGGTAGTATGCT
AGTCTTTCAGTCGCTGACCAAGCTTCTGGCTTTTGAACTGCGACAGCAACAGGAAAATAAGCAGCAGGAATGGCTCTTAT
TTGTCGATCAGTTAGAGACAGAGCTATCGCGCAGCCAATTTGACAGGGTCGAAAACGACAAAATCTACGTCAAACAGGAT
GGCAAAAATATAGCTTTAGGAAAATCTAGGAGTGATGATTTCCGCAAGACGGATGCTTCGGGACGTGGCTATCAGCCCAT
GGTTTATGGGCTCAAGGCTGCTCCGATTACTCAAAAGGGGAATCTTGTCCGCTTTCGTTTCCAGTTTGAAAATGATTTAG
AAAGAGAGTACATTTATCGTGTCCAAGATAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	70	96.552	0.676
comGF/cglF	Streptococcus mitis SK321	67.143	96.552	0.648
comGF/cglF	Streptococcus pneumoniae Rx1	65	96.552	0.628
comGF/cglF	Streptococcus pneumoniae D39	65	96.552	0.628
comGF/cglF	Streptococcus pneumoniae R6	65	96.552	0.628
comGF/cglF	Streptococcus pneumoniae TIGR4	65	96.552	0.628
comGF	Lactococcus lactis subsp. cremoris KW2	43.885	95.862	0.421
comYF	Streptococcus mutans UA140	41.379	100	0.414
comYF	Streptococcus mutans UA159	40.69	100	0.407