Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DQN71_RS10560 Genome accession   NZ_LS483471
Coordinates   2006914..2007879 (-) Length   321 a.a.
NCBI ID   WP_015605914.1    Uniprot ID   A0A512AE28
Organism   Streptococcus cristatus strain NCTC13807     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2001914..2012879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN71_RS10540 (NCTC13807_02003) pbp2a 2001942..2004164 (-) 2223 WP_015605911.1 penicillin-binding protein PBP2A -
  DQN71_RS10545 (NCTC13807_02004) - 2004316..2005203 (+) 888 WP_041826841.1 RluA family pseudouridine synthase -
  DQN71_RS10555 (NCTC13807_02005) - 2005685..2006878 (-) 1194 WP_111694592.1 acetate kinase -
  DQN71_RS10560 (NCTC13807_02006) comYH 2006914..2007879 (-) 966 WP_015605914.1 class I SAM-dependent methyltransferase Machinery gene
  DQN71_RS10565 (NCTC13807_02007) comGG 2007960..2008367 (-) 408 WP_015605915.1 competence type IV pilus minor pilin ComGG -
  DQN71_RS10570 (NCTC13807_02008) comGF/cglF 2008348..2008785 (-) 438 WP_015605916.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN71_RS10575 (NCTC13807_02009) comGE/cglE 2008769..2009038 (-) 270 WP_015605917.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQN71_RS10580 (NCTC13807_02010) comYD 2009028..2009462 (-) 435 WP_041826842.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN71_RS10585 (NCTC13807_02011) comYC 2009422..2009739 (-) 318 WP_015605919.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN71_RS10590 (NCTC13807_02012) comYB 2009736..2010752 (-) 1017 WP_015605920.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN71_RS10595 (NCTC13807_02013) comYA 2010700..2011641 (-) 942 WP_015605921.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN71_RS10600 (NCTC13807_02014) - 2011726..2012097 (-) 372 WP_015605922.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 321 a.a.        Molecular weight: 36601.63 Da        Isoelectric Point: 4.8000

>NTDB_id=1142340 DQN71_RS10560 WP_015605914.1 2006914..2007879(-) (comYH) [Streptococcus cristatus strain NCTC13807]
MKFEKIERAFHLLLENVQNIQNALGTNFYDALIEQNGIYLDGDTDLQEILKNNDKLRALHLTKEEWRRAYQFIFMKASQT
EPLQANHQFTPDSVGFLLSFLIDQLAQDERVDLLEIGSGTGNLAETLLNHTQKNMDYLGLEIDDLLIDLSASIAEVMNSK
AHFAQGDAVRPQVLKESDLIVSDLPVGYYPDDAVAARYEVASPDEHTYAHHLLMEQSLKYLKPGGYAIFLAPNNLLTSPQ
SHLLKKWLLSSAQLLAMISLPEKIFASRQSAKTLFVLRKQGESDIQPFIYPLQDLQSQDEILKFRESFQNWVKVSEIRTN
F

Nucleotide


Download         Length: 966 bp        

>NTDB_id=1142340 DQN71_RS10560 WP_015605914.1 2006914..2007879(-) (comYH) [Streptococcus cristatus strain NCTC13807]
ATGAAATTTGAAAAAATAGAACGAGCTTTTCACCTGCTTTTAGAAAACGTGCAAAATATCCAAAATGCGCTGGGAACTAA
TTTTTATGATGCTTTGATTGAGCAAAATGGGATTTATCTGGATGGAGATACGGACTTACAAGAAATTCTGAAAAACAATG
ACAAGCTTCGTGCCCTGCATTTGACCAAGGAAGAGTGGCGGCGGGCTTATCAGTTTATTTTTATGAAGGCTTCTCAGACA
GAGCCGCTTCAAGCCAATCATCAGTTCACACCTGATTCGGTCGGCTTCTTGCTGAGTTTTTTGATTGACCAGTTGGCACA
AGACGAGAGAGTTGATTTGCTGGAGATCGGCAGTGGAACAGGTAATTTGGCGGAGACTCTGCTCAACCACACACAAAAAA
ATATGGATTATCTAGGCCTAGAAATTGACGACTTACTGATTGATTTATCTGCCAGTATTGCTGAAGTCATGAATTCCAAG
GCACACTTTGCTCAAGGAGATGCGGTGCGGCCTCAGGTTCTGAAAGAAAGCGACTTGATTGTCAGTGATTTACCAGTGGG
TTATTATCCCGATGATGCAGTAGCTGCTCGCTATGAGGTTGCTAGCCCAGATGAGCATACCTACGCCCATCATCTCTTGA
TGGAGCAGTCGCTAAAATATTTGAAACCGGGAGGCTATGCTATCTTTCTTGCACCAAATAATCTGCTGACAAGCCCTCAG
AGTCACCTGCTGAAAAAATGGTTGCTTTCTAGCGCCCAGCTCTTGGCAATGATTTCCCTGCCAGAGAAGATTTTCGCAAG
CCGTCAGAGTGCCAAGACACTATTTGTCTTAAGGAAACAAGGCGAATCAGACATCCAGCCTTTTATCTACCCTTTGCAGG
ACCTGCAAAGTCAGGATGAAATCTTGAAGTTTCGTGAAAGTTTTCAAAACTGGGTCAAAGTTAGTGAAATTCGAACAAAT
TTCTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A512AE28

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

58.521

96.885

0.567
  comYH Streptococcus mutans UA140

58.521

96.885

0.567

Multiple sequence alignment