Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DQN71_RS10575 Genome accession   NZ_LS483471
Coordinates   2008769..2009038 (-) Length   89 a.a.
NCBI ID   WP_015605917.1    Uniprot ID   -
Organism   Streptococcus cristatus strain NCTC13807     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2003769..2014038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN71_RS10545 (NCTC13807_02004) - 2004316..2005203 (+) 888 WP_041826841.1 RluA family pseudouridine synthase -
  DQN71_RS10555 (NCTC13807_02005) - 2005685..2006878 (-) 1194 WP_111694592.1 acetate kinase -
  DQN71_RS10560 (NCTC13807_02006) comYH 2006914..2007879 (-) 966 WP_015605914.1 class I SAM-dependent methyltransferase Machinery gene
  DQN71_RS10565 (NCTC13807_02007) comGG 2007960..2008367 (-) 408 WP_015605915.1 competence type IV pilus minor pilin ComGG -
  DQN71_RS10570 (NCTC13807_02008) comGF/cglF 2008348..2008785 (-) 438 WP_015605916.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN71_RS10575 (NCTC13807_02009) comGE/cglE 2008769..2009038 (-) 270 WP_015605917.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQN71_RS10580 (NCTC13807_02010) comYD 2009028..2009462 (-) 435 WP_041826842.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN71_RS10585 (NCTC13807_02011) comYC 2009422..2009739 (-) 318 WP_015605919.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN71_RS10590 (NCTC13807_02012) comYB 2009736..2010752 (-) 1017 WP_015605920.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN71_RS10595 (NCTC13807_02013) comYA 2010700..2011641 (-) 942 WP_015605921.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN71_RS10600 (NCTC13807_02014) - 2011726..2012097 (-) 372 WP_015605922.1 DUF1033 family protein -
  DQN71_RS10605 (NCTC13807_02015) - 2012232..2013500 (-) 1269 WP_041826843.1 CapA family protein -
  DQN71_RS10615 (NCTC13807_02016) comW 2013743..2013970 (-) 228 WP_015605924.1 sigma(X)-activator ComW -

Sequence

Protein


Download         Length: 89 a.a.        Molecular weight: 10008.70 Da        Isoelectric Point: 9.9246

>NTDB_id=1142342 DQN71_RS10575 WP_015605917.1 2008769..2009038(-) (comGE/cglE) [Streptococcus cristatus strain NCTC13807]
MKASILLEALVAMAVFAAIASLLLGQISQSRQEQTRLLQEEEVLRVARMAMQTGQENLTVNGITVRQVKTDQQLTVYHQE
EKVLSVKKR

Nucleotide


Download         Length: 270 bp        

>NTDB_id=1142342 DQN71_RS10575 WP_015605917.1 2008769..2009038(-) (comGE/cglE) [Streptococcus cristatus strain NCTC13807]
ATGAAGGCTAGCATTTTGCTGGAGGCTCTGGTGGCAATGGCGGTTTTTGCAGCTATTGCCAGCCTCCTGCTTGGCCAGAT
TAGTCAGTCGCGGCAGGAACAGACTCGTTTATTGCAGGAGGAGGAAGTGCTGCGTGTTGCTCGGATGGCCATGCAGACGG
GGCAGGAAAATCTAACGGTCAACGGCATCACAGTCCGTCAAGTCAAGACCGACCAGCAATTAACCGTCTACCACCAAGAG
GAGAAGGTGCTCAGTGTTAAAAAACGTTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(5-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae D39

52.273

98.876

0.517
  comGE/cglE Streptococcus pneumoniae R6

52.273

98.876

0.517
  comGE/cglE Streptococcus pneumoniae TIGR4

52.273

98.876

0.517
  comGE/cglE Streptococcus pneumoniae Rx1

52.273

98.876

0.517
  comGE/cglE Streptococcus mitis SK321

51.724

97.753

0.506
  comGE/cglE Streptococcus mitis NCTC 12261

51.136

98.876

0.506
  comYE Streptococcus mutans UA140

41.573

100

0.416
  comYE Streptococcus mutans UA159

41.573

100

0.416

Multiple sequence alignment