Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   DQL01_RS11725 Genome accession   NZ_LS483451
Coordinates   2195905..2197230 (-) Length   441 a.a.
NCBI ID   WP_016397292.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2190905..2202230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS12805 - 2192589..2194192 (-) 1604 Protein_2196 YhgE/Pip family protein -
  DQL01_RS11705 - 2194371..2194913 (+) 543 WP_001158268.1 TetR/AcrR family transcriptional regulator -
  DQL01_RS11720 comE 2195156..2195908 (-) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  DQL01_RS11725 comD/comD2 2195905..2197230 (-) 1326 WP_016397292.1 competence system sensor histidine kinase ComD Regulator
  DQL01_RS11730 comC/comC2 2197251..2197376 (-) 126 WP_000799686.1 competence-stimulating peptide ComC Regulator
  DQL01_RS11740 rlmH 2197658..2198137 (-) 480 WP_061757162.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQL01_RS11745 htrA 2198320..2199501 (+) 1182 WP_000681597.1 S1C family serine protease Regulator
  DQL01_RS11750 spo0J 2199559..2200317 (+) 759 WP_050087436.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51423.01 Da        Isoelectric Point: 7.5816

>NTDB_id=1142106 DQL01_RS11725 WP_016397292.1 2195905..2197230(-) (comD/comD2) [Streptococcus pneumoniae strain 4041STDY6836166]
MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTEIVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQY
ERDRGLFLSLLLSLLYESTHNFLSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1142106 DQL01_RS11725 WP_016397292.1 2195905..2197230(-) (comD/comD2) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGGATTTACTTGGATTTGGGACAGTTATTGTTCATTTTTTAATTATTAGTCACAGTTACCGTTTAATTTGTAAAGGTCG
AATAAATAGAAAAGAATTATACGTTTTTGGTGCTTATACATTACTAACTGAAATAGTACTTGAATTTTCCTTTTATCTTC
TATATTTAGATAAAATAGGGATTGAAAGATTTTTATTTCCTTTGGGCTTATATTCCTATTTTCGATGGATGAAACAGTAT
GAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACTTT
CTCCTCTATAACAGGAGATAATTTTGTTTTACAATATCATTTCCCATTCTTTTTCGTTGTGACGGTGTTAACCTATTTTG
TTACATTAAAAATCATTTACTATTTCCATTTGGAACTAGCCTATTTTGACAAGGACTACCTTTATCCTTTCTTGAAAAAA
GTATTTTTTGCTTTACTATTGCTACATATTGTATCTTTCGTTTCAGATATGGTAAGTACGATTAAACATTTGAATAGTTT
TGGAAGTATTTTGTCATCTATTGTCTTTATCTCTCTCCTTTTGACCTTCTTTGCAATGAATTCTCATAAAGTTCAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTACACAGATGAAATTGTTGGTCTGTAT
AATGAAATCCGTGGTTTTCGACATGATTATGCTGGAATGCTTGTCAGCATGCAGATGGCAATTGACAGTGGTAATTTACA
GGAAATTGACAGAATTTACAATGAAGTTTTAGTCAAAGCAAATCATAAATTGCGTTCAGATAAGTACACTTACTTTGATT
TGAACAACATAGAAGACTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTTCCAATTGAACTATTGGATTTGGTTCGTATCATGAGCGTTTTATTGAA
TAATGCTGTCGAAGGATCGGCTGATAGCTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTTA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCCTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTCGGATTAAATAATGTGAAAGAACTACTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus pneumoniae TIGR4

99.773

100

0.998
  comD/comD1 Streptococcus pneumoniae Rx1

97.052

100

0.971
  comD/comD1 Streptococcus pneumoniae D39

97.052

100

0.971
  comD/comD1 Streptococcus pneumoniae R6

97.052

100

0.971
  comD Streptococcus mitis SK321

92.29

100

0.923
  comD Streptococcus mitis NCTC 12261

86.848

100

0.868
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.202

85.261

0.42
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.465

84.807

0.419

Multiple sequence alignment