Detailed information NTG1142053

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQL01_RS05025
• Genome accession: NZ_LS483451
• Coordinates: 932447..934687 (+)
• Length: 746 a.a.
• NCBI ID: WP_111702537.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4041STDY6836166
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 927447..939687

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL01_RS04980	-	927597..928565 (+)	969	WP_050090562.1	PhoH family protein	-
DQL01_RS04990	-	928758..929258 (+)	501	WP_111702535.1	GNAT family N-acetyltransferase	-
DQL01_RS04995	-	929261..929587 (+)	327	Protein_948	TfoX/Sxy family protein	-
DQL01_RS12375	ald	929888..930999 (-)	1112	Protein_949	alanine dehydrogenase	-
DQL01_RS05015	-	931176..931745 (+)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
DQL01_RS05020	comEA/celA/cilE	931813..932463 (+)	651	WP_000387337.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQL01_RS05025	comEC/celB	932447..934687 (+)	2241	WP_111702537.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQL01_RS05030	-	934866..935054 (+)	189	WP_010976492.1	hypothetical protein	-
DQL01_RS05035	-	935087..935674 (+)	588	WP_054378649.1	ATP-binding cassette domain-containing protein	-
DQL01_RS05040	-	935678..936862 (+)	1185	WP_111702538.1	hypothetical protein	-
DQL01_RS05045	infC	937172..937702 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
DQL01_RS05050	rpmI	937735..937935 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
DQL01_RS05055	rplT	937987..938346 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
DQL01_RS05060	-	938404..938784 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84800.51 Da
• Isoelectric Point: 9.3693

>NTDB_id=1142053 DQL01_RS05025 WP_111702537.1 932447..934687(+) (comEC/celB) [Streptococcus pneumoniae strain 4041STDY6836166]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKVKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDEGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPEMTLISVGKSNRMKLPHQETLTRLEAIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1142053 DQL01_RS05025 WP_111702537.1 932447..934687(+) (comEC/celB) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGTTTTGTTTTTCTACTAGTCTGCCTCTTTATCCAATTTCCTTGGAAATCAGCAG
GTAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAACTTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTCAACGGTGACAGTCTGTCCTTTCGTGGTAA
GTCTGATGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACTGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCACTCCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACTTCCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTAGGACATCTGGACACCGATTTTGAGGAGATGAATGAGCTTTATTCCAGTTTAGGAATTATTCACCTT
TTTGCCTTGTCAGGTATGCAGGTAGGGTTTTTCATGGACGGATTTAAGAAACTACTTTTACGATTGGGCTTGACACAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGTGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAGTCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGAAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGA
TGACTCTCATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACCCTGACCCGACTGGAAGCTATCAAT
AGTAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGCGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-681)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	96.515	100	0.965
comEC/celB	Streptococcus pneumoniae D39	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae R6	96.247	100	0.962
comEC/celB	Streptococcus pneumoniae Rx1	96.247	100	0.962
comEC/celB	Streptococcus mitis SK321	91.555	100	0.916
comEC/celB	Streptococcus mitis NCTC 12261	91.275	99.866	0.912
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44