Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DQL01_RS02915 Genome accession   NZ_LS483451
Coordinates   533794..534531 (+) Length   245 a.a.
NCBI ID   WP_061390076.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 528794..539531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS02885 - 530126..530413 (-) 288 WP_000777760.1 hypothetical protein -
  DQL01_RS02890 - 530423..530833 (-) 411 WP_001278301.1 HIT family protein -
  DQL01_RS02895 pptA 530901..531632 (+) 732 WP_000889919.1 ABC transporter ATP-binding protein Regulator
  DQL01_RS02900 - 531629..532678 (+) 1050 WP_000653771.1 ABC transporter permease -
  DQL01_RS02905 - 532846..533175 (-) 330 WP_000132575.1 hypothetical protein -
  DQL01_RS02910 - 533451..533789 (+) 339 WP_061390077.1 LytTR family DNA-binding domain-containing protein -
  DQL01_RS02915 comE/blpR 533794..534531 (+) 738 WP_061390076.1 response regulator transcription factor Regulator
  DQL01_RS02920 - 534545..535885 (+) 1341 WP_001017646.1 sensor histidine kinase -
  DQL01_RS02925 blpC 535956..536084 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  DQL01_RS02930 - 536141..537502 (-) 1362 WP_061390075.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28782.05 Da        Isoelectric Point: 6.7693

>NTDB_id=1142043 DQL01_RS02915 WP_061390076.1 533794..534531(+) (comE/blpR) [Streptococcus pneumoniae strain 4041STDY6836166]
MRIFVLEDDFSQQTRIETTIEKLLKEHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEKFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INKLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1142043 DQL01_RS02915 WP_061390076.1 533794..534531(+) (comE/blpR) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTTTTGAAAGAACA
TCATATCATTCCCAGCTCTTTTGAGGTCTTTGGTAAGCCAGACCAGCTACTGGCAGAGGTGCATGAGAAGGGCGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAACGAGGAGATGAAGGGGCTAGAAGTGGCTAGAAAGATTCGAGATCGGGAT
CCATATGCCCTTATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTTTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGAAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTGGCGGAAGATTGCTTTTATTTTAAATCAAAATTTGCCCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCGCCCAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAGCCCCGCCTCTTGCAGTGCCACCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCCCGTTATAAGGTCAGGGAAGTGTCTGAGGCC
ATCAATAAATTACACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.017

98.776

0.376
  comE Streptococcus infantis strain Atu-4

35.887

100

0.363

Multiple sequence alignment