Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   DQL12_RS11500 Genome accession   NZ_LS483450
Coordinates   2124374..2125036 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2119374..2130036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS11475 - 2119524..2119790 (-) 267 WP_001278167.1 Veg family protein -
  DQL12_RS11480 dnaB 2119792..2121144 (-) 1353 WP_111695787.1 replicative DNA helicase -
  DQL12_RS11485 rplI 2121188..2121640 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  DQL12_RS11490 - 2121637..2123610 (-) 1974 WP_050255532.1 DHH family phosphoesterase -
  DQL12_RS11495 hpf 2123746..2124294 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQL12_RS11500 comFC/cflB 2124374..2125036 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  DQL12_RS11505 comFA/cflA 2125033..2126331 (-) 1299 WP_000867616.1 DEAD/DEAH box helicase Machinery gene
  DQL12_RS11510 - 2126387..2127022 (+) 636 WP_000395742.1 YigZ family protein -
  DQL12_RS11515 cysK 2127307..2128227 (+) 921 WP_000029866.1 cysteine synthase A -
  DQL12_RS11525 - 2128302..2128840 (-) 539 Protein_2121 transposase -
  DQL12_RS11530 - 2128813..2129100 (+) 288 Protein_2122 transposase -
  DQL12_RS11535 tnpB 2129241..2129564 (-) 324 WP_000586643.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=1142022 DQL12_RS11500 WP_000649971.1 2124374..2125036(-) (comFC/cflB) [Streptococcus pneumoniae strain 4041STDY6583227]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1142022 DQL12_RS11500 WP_000649971.1 2124374..2125036(-) (comFC/cflB) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAATTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment