Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQL12_RS07060 Genome accession   NZ_LS483450
Coordinates   1324444..1325181 (-) Length   245 a.a.
NCBI ID   WP_050146391.1    Uniprot ID   A0AA95D8C1
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1319444..1330181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS07040 msrB 1320903..1321841 (-) 939 WP_000818203.1 peptide-methionine (R)-S-oxide reductase MsrB -
  DQL12_RS12275 - 1321908..1322060 (-) 153 WP_224782242.1 chlorohydrolase -
  DQL12_RS07050 thrB 1322136..1323005 (-) 870 WP_000692438.1 homoserine kinase -
  DQL12_RS07055 - 1323007..1324293 (-) 1287 WP_050146389.1 homoserine dehydrogenase -
  DQL12_RS07060 mecA 1324444..1325181 (-) 738 WP_050146391.1 adaptor protein MecA Regulator
  DQL12_RS07065 - 1325381..1326415 (-) 1035 WP_000461498.1 hypothetical protein -
  DQL12_RS07070 - 1326444..1327877 (-) 1434 WP_000565084.1 O-antigen polysaccharide polymerase Wzy family protein -
  DQL12_RS07075 - 1327893..1328879 (-) 987 WP_000446981.1 glycosyltransferase family 2 protein -
  DQL12_RS07080 - 1328881..1329984 (-) 1104 WP_000225894.1 glycosyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28395.21 Da        Isoelectric Point: 4.0199

>NTDB_id=1141982 DQL12_RS07060 WP_050146391.1 1324444..1325181(-) (mecA) [Streptococcus pneumoniae strain 4041STDY6583227]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLN
LQKIA

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1141982 DQL12_RS07060 WP_050146391.1 1324444..1325181(-) (mecA) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGAAAATGAAACAAATTAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGAATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGCTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTGACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTGCCAGATATGGAAGAATTGGCTCAAATGTCTCCAGATGAATTTAT
CAAAACCCTGGAAAAAAGCATCGCAGACAAAACCAAGGATGATATCGAAGCCATTCAATCTCTTGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAAGAGCAGGCTGAACAAGAAGCTGAGAGTAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTAGCTTTTGCCAAGACAGTGACTTTTGAAATGGAAACTTCTGAACTCTACAAAATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGCCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGCTCAGTCTTACAAGAGTATGGTCAAGTCTTGATGAGTCACGATGCAGTGCTCAAT
CTGCAAAAAATCGCCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

99.184

100

0.992
  mecA Streptococcus pneumoniae D39

99.184

100

0.992
  mecA Streptococcus pneumoniae R6

99.184

100

0.992
  mecA Streptococcus pneumoniae TIGR4

98.776

100

0.988
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.486
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.482
  mecA Streptococcus mutans UA159

47.755

100

0.478

Multiple sequence alignment