Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   DQK98_RS00245 Genome accession   NZ_LS483449
Coordinates   43523..44872 (+) Length   449 a.a.
NCBI ID   WP_050227636.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836170     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 38523..49872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK98_RS00220 plsX 38642..39634 (+) 993 WP_050087054.1 phosphate acyltransferase PlsX -
  DQK98_RS00225 - 39640..39873 (+) 234 WP_000136447.1 acyl carrier protein -
  DQK98_RS00230 - 39910..40209 (+) 300 Protein_36 transposase family protein -
  DQK98_RS00235 blpU 40412..40642 (+) 231 WP_001093068.1 bacteriocin-like peptide BlpU -
  DQK98_RS12065 - 40645..40770 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  DQK98_RS00240 comA 41357..43510 (+) 2154 WP_111688007.1 peptide cleavage/export ABC transporter ComA Regulator
  DQK98_RS00245 comB 43523..44872 (+) 1350 WP_050227636.1 competence pheromone export protein ComB Regulator
  DQK98_RS00250 purC 45042..45749 (+) 708 WP_000043300.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  DQK98_RS12185 - 45751..45894 (+) 144 WP_050167432.1 hypothetical protein -
  DQK98_RS00260 - 45951..49676 (+) 3726 WP_111688009.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49607.54 Da        Isoelectric Point: 5.3923

>NTDB_id=1141881 DQK98_RS00245 WP_050227636.1 43523..44872(+) (comB) [Streptococcus pneumoniae strain 4041STDY6836170]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLETLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTIHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1141881 DQK98_RS00245 WP_050227636.1 43523..44872(+) (comB) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGAGCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAAACCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGAAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGATTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTAGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTAGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.886

100

0.989
  comB Streptococcus pneumoniae D39

98.664

100

0.987
  comB Streptococcus pneumoniae R6

98.664

100

0.987
  comB Streptococcus pneumoniae Rx1

98.664

100

0.987
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.556

100

0.557

Multiple sequence alignment