Detailed information NTG1141741

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DQL20_RS03730
• Genome accession: NZ_LS483444
• Coordinates: 683275..684225 (+)
• Length: 316 a.a.
• NCBI ID: WP_006596646.1
• Uniprot ID: E7SCC2
• Organism: Streptococcus australis strain NCTC13166
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 678275..689225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL20_RS03705 (NCTC11371_00735)	-	678323..679657 (+)	1335	WP_006596650.1	DUF1958 domain-containing protein	-
DQL20_RS03710 (NCTC11371_00736)	-	679730..680893 (+)	1164	WP_006596649.1	MFS transporter	-
DQL20_RS03715 (NCTC11371_00737)	-	680974..682263 (+)	1290	WP_006596648.1	D-alanyl-D-alanine carboxypeptidase family protein	-
DQL20_RS03720 (NCTC11371_00738)	-	682404..682958 (+)	555	WP_006596647.1	hypothetical protein	-
DQL20_RS03730 (NCTC11371_00739)	coiA	683275..684225 (+)	951	WP_006596646.1	competence protein CoiA	Machinery gene
DQL20_RS03735 (NCTC11371_00740)	pepF	684295..686097 (+)	1803	WP_006596645.1	oligoendopeptidase F	Regulator
DQL20_RS03740 (NCTC11371_00741)	-	686099..686812 (+)	714	WP_006596644.1	O-methyltransferase	-
DQL20_RS03745 (NCTC11371_00742)	-	686890..687831 (+)	942	WP_006596643.1	peptidylprolyl isomerase	-
DQL20_RS03755 (NCTC11371_00743)	-	688122..688604 (+)	483	WP_006596642.1	LURP-one-related/scramblase family protein	-

Sequence

Protein

• Length: 316 a.a.
• Molecular weight: 37991.95 Da
• Isoelectric Point: 9.5521

>NTDB_id=1141741 DQL20_RS03730 WP_006596646.1 683275..684225(+) (coiA) [Streptococcus australis strain NCTC13166]
MFIAADAKQQRWNCLEKVPMRRDGPFVCLLCGKEVRLKKGRVMRPHFAHVNLEACPFHHETESPEHLELKLELYRWAKQN
TQAEVESPLQALQQIADVLLPDQKIALEVQCSSLSMERLKERSDAYRMHGYQVYWLLGKNLWLKKSLSALQEGFVYFSQN
RGFHLWELDLEQQEVRLHYLIHQDLRGRLHYRTQHFPFYGGSLLEVLRTPYAQQGLQRMTVPLDRQFKDYLRQQLYYRHP
KWMALQEQLYLKGKHLLDLNLEAFYPLCRPLKSLHFIQIKGDWRSYYQNFMTYYLQTGMKATQTLYSPRFYQNWKA

Nucleotide

• Length: 951 bp

>NTDB_id=1141741 DQL20_RS03730 WP_006596646.1 683275..684225(+) (coiA) [Streptococcus australis strain NCTC13166]
ATGTTTATTGCGGCTGATGCAAAGCAACAGCGTTGGAATTGTTTGGAGAAGGTTCCGATGAGAAGAGATGGTCCCTTTGT
CTGTCTCCTGTGTGGAAAGGAAGTCCGCTTAAAGAAAGGGCGAGTGATGCGTCCTCATTTTGCTCACGTCAACCTAGAGG
CTTGTCCCTTCCATCATGAAACGGAGAGTCCAGAACATTTGGAGTTAAAGTTGGAGCTTTATCGATGGGCCAAACAAAAT
ACCCAAGCTGAAGTGGAAAGTCCTTTGCAGGCTCTCCAACAGATTGCGGATGTTCTCCTTCCAGATCAAAAGATTGCCTT
AGAAGTGCAATGTAGTTCCTTGTCTATGGAGCGTTTAAAAGAACGGAGCGATGCCTATCGCATGCATGGTTATCAAGTTT
ATTGGTTATTGGGGAAAAACTTATGGCTCAAGAAAAGCTTGTCAGCTCTGCAAGAAGGTTTTGTCTATTTTAGCCAAAAT
AGGGGCTTTCATCTCTGGGAGTTGGACCTAGAACAGCAAGAAGTTCGGCTCCACTATCTCATTCATCAAGATTTGCGAGG
GCGTCTTCATTATCGGACTCAACATTTTCCTTTTTATGGAGGGAGCTTATTAGAAGTTTTGCGGACCCCTTATGCCCAAC
AAGGCTTGCAACGAATGACGGTCCCTCTAGACCGACAGTTTAAGGACTACCTTCGTCAGCAGTTGTATTACCGGCATCCT
AAGTGGATGGCTCTTCAGGAACAACTCTATCTGAAAGGAAAGCATCTCCTGGACTTGAACTTGGAAGCCTTTTATCCCCT
GTGTCGGCCACTGAAGTCTCTCCATTTTATCCAGATTAAGGGAGACTGGCGAAGCTATTACCAGAACTTTATGACTTATT
ATCTCCAAACCGGAATGAAAGCGACGCAGACTCTTTATTCGCCTCGTTTTTATCAGAACTGGAAAGCTTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (25-267)

3D structure

• AlphaFold DB: E7SCC2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	49.682	99.367	0.494
coiA	Streptococcus pneumoniae TIGR4	48.726	99.367	0.484
coiA	Streptococcus pneumoniae Rx1	48.408	99.367	0.481
coiA	Streptococcus pneumoniae D39	48.408	99.367	0.481
coiA	Streptococcus pneumoniae R6	48.408	99.367	0.481
coiA	Lactococcus lactis subsp. cremoris KW2	40.81	100	0.415