Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   DQL20_RS03630 Genome accession   NZ_LS483444
Coordinates   660626..662866 (+) Length   746 a.a.
NCBI ID   WP_006596665.1    Uniprot ID   E7SCE1
Organism   Streptococcus australis strain NCTC13166     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 655626..667866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL20_RS03610 (NCTC11371_00716) - 655794..656540 (-) 747 WP_006596670.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DQL20_RS03615 (NCTC11371_00717) - 656640..658979 (-) 2340 WP_006596669.1 cation-translocating P-type ATPase -
  DQL20_RS03620 (NCTC11371_00718) - 659117..659860 (+) 744 WP_006596667.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DQL20_RS03625 (NCTC11371_00719) comEA/celA/cilE 659965..660642 (+) 678 WP_006596934.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQL20_RS03630 (NCTC11371_00720) comEC/celB 660626..662866 (+) 2241 WP_006596665.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQL20_RS03635 (NCTC11371_00721) - 662929..663594 (+) 666 WP_006596664.1 DUF805 domain-containing protein -
  DQL20_RS03640 (NCTC11371_00722) holA 663572..664609 (+) 1038 WP_006596663.1 DNA polymerase III subunit delta -
  DQL20_RS03645 (NCTC11371_00723) sodA 664681..665286 (+) 606 WP_006596662.1 superoxide dismutase SodA -
  DQL20_RS03650 (NCTC11371_00724) - 665539..667011 (+) 1473 WP_006596922.1 helicase HerA-like domain-containing protein -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 86250.03 Da        Isoelectric Point: 9.3025

>NTDB_id=1141740 DQL20_RS03630 WP_006596665.1 660626..662866(+) (comEC/celB) [Streptococcus australis strain NCTC13166]
MLQWIRSLHIHLFHLTLPVLALYYWMYTEHWLALIFLLAFLILFRRRYGDKRFLCLIGFLSLFALCFAFRIEQGRRESSD
HRVPSVIQLLPDTIKVNGDALSFRAKSGSRTFQVFYQLQSEEEQAYFKHLDHGLELRIKGELEPPTKQRNFMGFDYQAYL
KTQGIYHLLKISHILEKRPAEPRDFIGLLSSWRRKALVWVHQHFPQPMSHYMTGLLFGFLDVEFEEMSQLYSNLGIIHLF
ALSGMQVAFFLDAFRRFFLRLGLEQEKVVILLYPFSLLYAGMTGFSVSVVRSVLQKLLAQAGLKGMENMGVTLLLLIVLL
PSSLLTAGGLLSCAYAFILTLTSSEEEKSGIRKVVKESLVLTLGVLPFLIFFFGEYQPWSLPLTFIFSLLFDLLLLPGLS
VVFLLSFFYPLTFWNPFFVWMEKSMEYIASFTSKSLVFGQPSIYFFILLLCLLACLYEMRKVKKWRYLFLLLVCSVFAIV
KHPLENEITIIDIGQGDSILLRDWRGKTILIDTGGKVDFGQKEEWKNRRSTSNAERTLLPYLKSRGIDQIDHMILTHTDT
DHMGDLEVLATKVRIKEINISKGSLKKDSFVRLLKRLNLPVKTLEIGNRLSIFDGSAEVLYPVEVGDGSNNDSIVLYGRF
YGWSFLFTGDLEEEGEKTLLARYPQLRVDVLKAGHHGSKGSSHPAFLEKIQAKIALISAGEKNRYQHPHQETLERFEELQ
MTVFRTDQQGAIRFRGWNQWKIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=1141740 DQL20_RS03630 WP_006596665.1 660626..662866(+) (comEC/celB) [Streptococcus australis strain NCTC13166]
ATGTTACAGTGGATTAGAAGTCTCCATATTCATTTATTTCATCTCACCCTGCCGGTCTTAGCTCTCTATTACTGGATGTA
CACGGAGCACTGGCTCGCTCTAATCTTCCTGCTGGCTTTCCTCATCTTGTTTAGGAGACGCTACGGGGACAAACGATTTT
TGTGCCTCATAGGGTTTCTTTCCCTCTTTGCCCTTTGTTTTGCTTTCCGGATCGAACAAGGAAGACGAGAGTCAAGCGAT
CATAGGGTCCCAAGTGTTATTCAGCTTTTACCGGATACCATCAAGGTGAATGGAGATGCTTTATCCTTTCGTGCCAAGTC
AGGTAGCCGTACTTTTCAGGTTTTCTACCAGCTTCAGTCAGAGGAAGAACAAGCCTATTTTAAACACCTGGATCATGGGC
TAGAATTACGGATCAAAGGGGAATTAGAACCCCCGACAAAACAGCGGAATTTTATGGGTTTTGATTACCAGGCTTATCTG
AAAACACAAGGGATCTATCACCTTTTGAAAATTAGCCACATCCTTGAAAAGAGACCTGCTGAGCCTAGAGATTTCATAGG
TCTGCTGTCTAGTTGGAGGAGGAAGGCCCTTGTATGGGTTCACCAGCATTTTCCCCAGCCCATGAGTCACTATATGACGG
GCTTGCTTTTTGGTTTTTTAGACGTCGAGTTTGAGGAAATGAGCCAGCTGTATTCGAACTTGGGGATTATTCATCTGTTT
GCCTTGTCAGGCATGCAGGTTGCCTTTTTCTTAGATGCCTTTCGACGATTCTTTCTCCGCTTGGGATTGGAACAGGAGAA
GGTTGTAATCCTCCTCTATCCGTTTTCCCTTCTTTATGCTGGGATGACGGGGTTTTCGGTTTCAGTCGTTCGAAGCGTCT
TACAGAAACTCCTGGCCCAGGCTGGGCTCAAAGGAATGGAAAATATGGGAGTCACCCTTCTTTTATTGATTGTTCTCCTA
CCTTCCTCCTTATTAACTGCTGGAGGTCTCTTATCCTGCGCCTATGCCTTTATATTGACGCTCACCTCTTCTGAAGAGGA
GAAGTCAGGAATCCGAAAAGTCGTCAAGGAAAGTCTAGTGTTAACACTAGGGGTTCTTCCTTTTCTCATCTTTTTCTTTG
GAGAATACCAACCCTGGTCTCTTCCTCTAACCTTTATTTTTTCTCTCTTATTTGATCTTCTGTTGTTACCAGGTCTGAGT
GTCGTCTTTCTCCTCTCCTTTTTCTATCCCTTGACCTTCTGGAATCCTTTCTTCGTCTGGATGGAAAAAAGTATGGAGTA
TATAGCGAGCTTCACTAGCAAATCCTTGGTTTTTGGACAGCCAAGCATTTATTTTTTCATCTTGCTTTTGTGCTTGCTGG
CTTGTCTCTATGAGATGCGAAAGGTTAAGAAATGGAGATATCTTTTTCTACTCTTAGTATGCTCTGTATTTGCTATCGTG
AAGCATCCTTTAGAAAATGAGATTACCATCATTGATATTGGTCAAGGTGATAGTATTTTGTTGCGTGATTGGCGAGGAAA
AACGATCTTAATTGATACAGGAGGAAAAGTGGACTTTGGCCAAAAGGAGGAATGGAAGAACCGAAGGTCTACTAGCAATG
CAGAACGGACCCTGCTCCCCTATCTCAAGAGCAGGGGGATTGACCAGATTGATCATATGATTCTCACGCATACTGACACA
GATCATATGGGAGATTTGGAAGTGCTTGCGACTAAGGTTAGGATAAAGGAAATAAATATTTCTAAGGGAAGCTTAAAGAA
AGACTCTTTTGTCCGTTTGCTCAAACGGTTGAACTTACCGGTGAAAACGCTAGAGATTGGAAATCGGTTATCAATCTTTG
ATGGGAGTGCAGAAGTCCTCTATCCGGTAGAAGTAGGAGATGGAAGTAATAATGATTCCATTGTTCTCTATGGACGCTTT
TATGGGTGGTCCTTCCTTTTTACAGGAGATTTAGAAGAAGAAGGGGAAAAGACCTTGTTAGCCCGTTATCCTCAACTGCG
CGTGGATGTCCTAAAAGCAGGCCACCATGGTTCTAAGGGTTCTTCTCACCCTGCCTTCTTAGAGAAAATCCAAGCAAAAA
TTGCCTTGATATCTGCGGGTGAAAAAAATCGTTACCAGCACCCTCATCAGGAAACCTTGGAGCGTTTCGAAGAGTTACAA
ATGACTGTTTTTCGTACAGACCAGCAAGGAGCGATTCGTTTTAGAGGGTGGAATCAGTGGAAGATTGAAACCGTTCGATA
G

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)

Domain of unknown function (DUF4131) (DUF4131)

(32-172)

Competence protein (Competence)

(215-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E7SCE1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

52.863

100

0.532
  comEC/celB Streptococcus mitis SK321

52.59

100

0.531
  comEC/celB Streptococcus pneumoniae TIGR4

52.394

100

0.528
  comEC/celB Streptococcus pneumoniae Rx1

52.128

100

0.525
  comEC/celB Streptococcus pneumoniae D39

52.128

100

0.525
  comEC/celB Streptococcus pneumoniae R6

52.128

100

0.525
  comEC Lactococcus lactis subsp. cremoris KW2

44.892

99.732

0.448

Multiple sequence alignment