Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DQL20_RS02675 Genome accession   NZ_LS483444
Coordinates   486227..488098 (+) Length   623 a.a.
NCBI ID   WP_006596840.1    Uniprot ID   E7SD19
Organism   Streptococcus australis strain NCTC13166     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 481227..493098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL20_RS02660 (NCTC11371_00528) fmt 483230..484165 (+) 936 WP_006596843.1 methionyl-tRNA formyltransferase -
  DQL20_RS02665 (NCTC11371_00529) rsmB 484155..485468 (+) 1314 WP_040803119.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQL20_RS02670 (NCTC11371_00530) - 485490..486230 (+) 741 WP_006596841.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQL20_RS02675 (NCTC11371_00531) stkP 486227..488098 (+) 1872 WP_006596840.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQL20_RS02680 (NCTC11371_00532) liaF 488229..488924 (+) 696 WP_006596839.1 cell wall-active antibiotics response protein LiaF -
  DQL20_RS02685 (NCTC11371_00533) - 488921..489940 (+) 1020 WP_006596838.1 sensor histidine kinase -
  DQL20_RS02690 (NCTC11371_00534) - 489918..490550 (+) 633 WP_040803116.1 response regulator transcription factor -
  DQL20_RS02695 (NCTC11371_00535) - 490595..492001 (+) 1407 WP_006596952.1 Cof-type HAD-IIB family hydrolase -
  DQL20_RS02700 (NCTC11371_00536) - 491998..492366 (+) 369 WP_006596835.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 68673.97 Da        Isoelectric Point: 5.7782

>NTDB_id=1141730 DQL20_RS02675 WP_006596840.1 486227..488098(+) (stkP) [Streptococcus australis strain NCTC13166]
MIQIGKIFAGRYKIIRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPNIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTQGIIHRDLKPQNVLLTSDGNAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKASIQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIEENKNVP
QALENVVIKATAKKLSDRYKSVAEMYVDLSSCLSYERRNEKKLVFDDASKADTKTLPKVNVVPKPAPLPTSEARPTVHED
RPVVSEDRTAPVSPKNKARRRLRTRYKVLFVALALVLAAFAFLLYMSPANKTVPDVSGKTVAEARAIIEDQDLQVGDEKE
EYSDSVLEGYVIRTNPNAGAQKKENSKVDLVVSKGPSTFDMPDYTGMSREYVENDLKTTYKLSSKLISIEEVETNEVEPG
IVMEQSPVAGQKYDLSSKTKIVLKVSKESNSIELPSYVGSYYEFAVSNLVQIYGVKEANIERKTTSHLPAGVEVLPGQIV
SQTPEAQSSIDIKKTRIVLTVYEPKTEPSSSTKASSSSSESSSSTTVEFHSNTDPSATTEPES

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=1141730 DQL20_RS02675 WP_006596840.1 486227..488098(+) (stkP) [Streptococcus australis strain NCTC13166]
ATGATTCAAATCGGCAAAATTTTTGCCGGACGATATAAGATAATCCGCCAAATCGGGCGTGGAGGAATGGCAGACGTCTA
CCTCGCTCGGGATTTAATCTTAGATGGTGAAGAAGTTGCAGTTAAAGTACTGAGGACCAATTACCAAACAGATCCAATTG
CAGTTGCTCGCTTCCAACGAGAGGCCAAAGCGATGGCAGATTTGGATCATCCAAATATCGTTCGGATCACGGATATCGGT
GAAGAGGATGGCCAGCAATACTTGGCGATGGAATATGTCGCTGGTTTGGACTTGAAACGCTATATCAAAGAAAATGCTCC
TCTCTCAAATGAAGAAGCTGTTCGCTTGATGGGGCAAATCCTTCTTGCTATGCGCTTGGCGCACACGCAAGGCATTATTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACATCGGACGGAAATGCCAAGGTTTCTGACTTTGGGATTGCAGTAGCC
TTTGCAGAGACCAGTCTCACCCAGACCAACTCTATGTTGGGTTCGGTTCATTATTTATCACCAGAGCAAGCCAGAGGATC
GAAGGCTTCTATTCAAAGTGATATCTATGCAATGGGGATCATTTTCTACGAAATGCTGACGGGTCATATCCCTTATGATG
GGGATAGTGCAGTGACCATTGCGCTGCAACATTTCCAAAAACCACTTCCGTCCATCATTGAAGAGAACAAAAATGTTCCG
CAGGCTTTGGAAAATGTTGTTATTAAGGCCACAGCAAAGAAACTATCCGATCGCTATAAGTCGGTAGCTGAAATGTATGT
CGACTTGTCAAGTTGTCTATCTTATGAACGCCGTAATGAGAAAAAATTAGTCTTTGATGACGCTTCAAAAGCGGATACCA
AGACCTTACCAAAGGTGAACGTGGTTCCAAAACCGGCTCCACTTCCAACATCGGAAGCTCGTCCTACAGTTCATGAGGAC
CGACCAGTGGTTTCAGAGGATCGAACAGCTCCAGTTTCTCCAAAAAATAAGGCACGTCGTCGTTTGCGGACGCGCTACAA
GGTCTTGTTTGTAGCCCTAGCTTTGGTACTAGCTGCTTTTGCCTTTCTTCTTTATATGAGTCCAGCCAACAAAACAGTTC
CGGATGTATCTGGAAAAACGGTAGCAGAAGCTCGGGCTATCATTGAAGATCAGGATCTTCAAGTAGGAGACGAAAAAGAA
GAATACAGTGATTCGGTGCTGGAGGGTTATGTAATCCGTACCAATCCAAATGCAGGAGCTCAGAAAAAGGAAAACAGCAA
GGTTGATTTGGTTGTCTCGAAAGGGCCAAGCACCTTTGATATGCCGGACTATACTGGTATGTCTAGAGAATATGTGGAAA
ACGATCTGAAAACCACCTATAAGCTTTCTAGCAAGCTGATTTCGATTGAAGAAGTCGAGACCAATGAAGTGGAACCAGGA
ATCGTTATGGAGCAATCTCCTGTCGCTGGTCAAAAATATGATTTGTCTTCTAAAACAAAGATTGTTCTGAAAGTATCGAA
GGAAAGTAATTCCATCGAATTACCAAGTTATGTCGGTTCTTATTATGAATTTGCTGTCTCTAATCTCGTCCAGATCTATG
GGGTGAAGGAAGCAAATATTGAACGGAAGACCACATCGCATCTTCCGGCTGGTGTAGAAGTCCTACCAGGTCAAATTGTG
AGTCAGACTCCAGAAGCTCAATCGAGCATCGATATTAAAAAGACTCGCATTGTCTTGACTGTATACGAACCGAAGACGGA
ACCATCAAGTAGTACGAAAGCTTCAAGCAGTTCATCAGAAAGTTCAAGCTCTACAACAGTGGAATTCCATTCCAATACGG
ACCCTTCGGCGACTACTGAACCAGAATCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-255)

PASTA domain (PASTA)

(513-582)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-507)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E7SD19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

61.327

99.197

0.608
  stkP Streptococcus pneumoniae D39

61.165

99.197

0.607
  stkP Streptococcus pneumoniae R6

61.165

99.197

0.607
  stkP Streptococcus pneumoniae Rx1

61.003

99.197

0.605
  pknB Streptococcus mutans UA159

58.118

86.998

0.506
  stkP/pknB Streptococcus salivarius strain HSISS4

52.357

95.345

0.499

Multiple sequence alignment