Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQN45_RS03710 Genome accession   NZ_LS483438
Coordinates   729187..730404 (+) Length   405 a.a.
NCBI ID   WP_014550481.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12975     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 724187..735404
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN45_RS03690 (NCTC12975_00737) corC 725152..726051 (-) 900 WP_042593501.1 CNNM family magnesium/cobalt transport protein CorC -
  DQN45_RS03695 (NCTC12975_00738) ampD 726684..727235 (-) 552 WP_042593499.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQN45_RS03700 (NCTC12975_00739) pilA 727350..727799 (+) 450 WP_042593498.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQN45_RS03705 (NCTC12975_00740) pilB 727796..729190 (+) 1395 WP_011271972.1 GspE/PulE family protein Machinery gene
  DQN45_RS03710 (NCTC12975_00741) pilC 729187..730404 (+) 1218 WP_014550481.1 type II secretion system F family protein Machinery gene
  DQN45_RS03715 (NCTC12975_00742) pilD 730401..731093 (+) 693 WP_014550482.1 A24 family peptidase Machinery gene
  DQN45_RS03720 (NCTC12975_00743) rho 731147..732409 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  DQN45_RS03725 (NCTC12975_00744) metJ 732657..732974 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DQN45_RS03730 (NCTC12975_00745) cueR 732988..733374 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQN45_RS03735 (NCTC12975_00746) - 733451..733657 (+) 207 WP_005666692.1 heavy-metal-associated domain-containing protein -
  DQN45_RS03740 (NCTC12975_00747) - 733743..733949 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQN45_RS03745 (NCTC12975_00748) - 734023..734229 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46089.34 Da        Isoelectric Point: 9.9010

>NTDB_id=1141562 DQN45_RS03710 WP_014550481.1 729187..730404(+) (pilC) [Haemophilus influenzae strain NCTC12975]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNKWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1141562 DQN45_RS03710 WP_014550481.1 729187..730404(+) (pilC) [Haemophilus influenzae strain NCTC12975]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTA
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACAAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTACCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.983
  pilC Haemophilus influenzae Rd KW20

96.798

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.5

98.765

0.38

Multiple sequence alignment