Detailed information NTG1141166

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DQN36_RS09055
• Genome accession: NZ_LS483425
• Coordinates: 1817406..1818629 (+)
• Length: 407 a.a.
• NCBI ID: WP_063812448.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13737
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1812406..1823629

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN36_RS09040 (NCTC13737_01782)	-	1815546..1816320 (-)	775	Protein_1669	IS30 family transposase	-
DQN36_RS09050 (NCTC13737_01784)	rlmH	1816715..1817194 (-)	480	WP_002981964.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DQN36_RS09055 (NCTC13737_01785)	htrA	1817406..1818629 (+)	1224	WP_063812448.1	S1C family serine protease	Regulator
DQN36_RS09060 (NCTC13737_01786)	spo0J	1818718..1819494 (+)	777	WP_014407987.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42776.38 Da
• Isoelectric Point: 7.3920

>NTDB_id=1141166 DQN36_RS09055 WP_063812448.1 1817406..1818629(+) (htrA) [Streptococcus pyogenes strain NCTC13737]
MPSMKHILKSLSILLVGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGTVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide

• Length: 1224 bp

>NTDB_id=1141166 DQN36_RS09055 WP_063812448.1 1817406..1818629(+) (htrA) [Streptococcus pyogenes strain NCTC13737]
ATGCCAAGTATGAAACATATCTTAAAATCCTTAAGTATTTTACTAGTTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTCAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTACTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGACGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• PDZ domain (PDZ_2) (301-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.634	99.263	0.612
htrA	Streptococcus gordonii str. Challis substr. CH1	55.473	98.771	0.548
htrA	Streptococcus mitis NCTC 12261	52.941	100	0.531
htrA	Streptococcus pneumoniae Rx1	52.696	100	0.528
htrA	Streptococcus pneumoniae D39	52.696	100	0.528
htrA	Streptococcus pneumoniae R6	52.696	100	0.528
htrA	Streptococcus pneumoniae TIGR4	52.696	100	0.528