Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQN40_RS01965 Genome accession   NZ_LS483413
Coordinates   364851..365612 (+) Length   253 a.a.
NCBI ID   WP_003059809.1    Uniprot ID   A0A9X5LVZ2
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 359851..370612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN40_RS01950 (NCTC7136_00401) - 360110..361678 (-) 1569 WP_084916654.1 ABC transporter substrate-binding protein/permease -
  DQN40_RS01955 (NCTC7136_00402) - 361877..363802 (+) 1926 WP_015016681.1 DUF2207 domain-containing protein -
  DQN40_RS01960 (NCTC7136_00403) - 363868..364707 (+) 840 WP_012766572.1 undecaprenyl-diphosphate phosphatase -
  DQN40_RS01965 (NCTC7136_00404) mecA 364851..365612 (+) 762 WP_003059809.1 adaptor protein MecA Regulator
  DQN40_RS01970 (NCTC7136_00405) - 365619..366788 (+) 1170 WP_003054822.1 MraY family glycosyltransferase -
  DQN40_RS01975 (NCTC7136_00406) sufC 366901..367671 (+) 771 WP_003061584.1 Fe-S cluster assembly ATPase SufC -
  DQN40_RS01980 (NCTC7136_00407) sufD 367768..369030 (+) 1263 WP_084916651.1 Fe-S cluster assembly protein SufD -
  DQN40_RS01985 (NCTC7136_00408) - 369061..370287 (+) 1227 WP_003062308.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29071.72 Da        Isoelectric Point: 4.0755

>NTDB_id=1140685 DQN40_RS01965 WP_003059809.1 364851..365612(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPELLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1140685 DQN40_RS01965 WP_003059809.1 364851..365612(+) (mecA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGATAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTTAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCTGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACCAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTTTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.8

98.814

0.64
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482

Multiple sequence alignment