Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQN21_RS11165 Genome accession   NZ_LS483409
Coordinates   2226171..2228318 (+) Length   715 a.a.
NCBI ID   WP_077497737.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2221171..2233318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS11115 (NCTC13773_02259) - 2222234..2222533 (-) 300 WP_013643490.1 DUF3884 family protein -
  DQN21_RS11120 (NCTC13773_02260) - 2222559..2222741 (-) 183 WP_013643491.1 hypothetical protein -
  DQN21_RS11125 (NCTC13773_02261) - 2222823..2223032 (-) 210 WP_013643492.1 helix-turn-helix domain-containing protein -
  DQN21_RS11130 (NCTC13773_02262) - 2223022..2224035 (-) 1014 WP_077497732.1 bacteriocin biosynthesis protein -
  DQN21_RS11150 (NCTC13773_02263) - 2225093..2225290 (-) 198 WP_009855009.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DQN21_RS11155 (NCTC13773_02264) - 2225309..2225560 (-) 252 WP_009855010.1 bacteriocin class II family protein -
  DQN21_RS11160 (NCTC13773_02265) - 2225807..2226064 (+) 258 WP_009855011.1 hypothetical protein -
  DQN21_RS11165 (NCTC13773_02266) comA/nlmT 2226171..2228318 (+) 2148 WP_077497737.1 peptide cleavage/export ABC transporter Regulator
  DQN21_RS11170 (NCTC13773_02267) - 2228330..2229724 (+) 1395 WP_074658230.1 bacteriocin secretion accessory protein -
  DQN21_RS11175 (NCTC13773_02268) - 2229916..2230590 (+) 675 WP_077497739.1 CPBP family intramembrane glutamic endopeptidase -
  DQN21_RS12635 (NCTC13773_02269) - 2230608..2230778 (+) 171 WP_157769870.1 hypothetical protein -
  DQN21_RS11180 (NCTC13773_02270) - 2230796..2231467 (+) 672 WP_061458109.1 CPBP family intramembrane glutamic endopeptidase -
  DQN21_RS11185 (NCTC13773_02271) rsmA 2231760..2232632 (-) 873 WP_009855016.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  DQN21_RS11190 (NCTC13773_02272) - 2232702..2233226 (-) 525 WP_077497742.1 DUF1697 domain-containing protein -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 79940.67 Da        Isoelectric Point: 7.1614

>NTDB_id=1140589 DQN21_RS11165 WP_077497737.1 2226171..2228318(+) (comA/nlmT) [Streptococcus gallolyticus strain NCTC13773]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKIPHYYVIYKAKKDYLIIGDPDSSVGVTKMSKAHFAKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNHLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNANLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVVILWYGSRLVMSGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDGRQLLNDSHFLQG
DIVFDNVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIESMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGQVIEEGHHKQLIQNQGFYAQLFHE

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=1140589 DQN21_RS11165 WP_077497737.1 2226171..2228318(+) (comA/nlmT) [Streptococcus gallolyticus strain NCTC13773]
ATGAGAAGATATAAATATGTTAGTCAGATTGATTTGCGAGACTGTGGTGTGGCAGCTTTGGCATCAGTTGCCAAGCATTA
TGGATCAGATTTCTCGCTGGCTCATTTGAGAGAATTAGCCAAAACAACTAAGGAAGGGACAACAGCATTAGGGATAGTTG
AGGCAGCTAAAGCAATCGGCTTTGAAACACGCGCCATTCAGGCTAATATGGAACTGTTTGATATGGCTGATATTCCCTAT
CCTTTTATTGTTCATGTTAATAAAGAAGGCAAAATCCCGCATTACTATGTTATCTACAAAGCCAAAAAAGATTATCTTAT
TATCGGTGACCCTGATTCGAGCGTTGGGGTCACTAAAATGTCCAAAGCACATTTTGCCAAAGAATGGACTGGAGTTGCTA
TCTTTTTAGCGCCTGCTCCGCATTATCAACCGCATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAATATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCATTTGCAATCCACTCTTGGCATTGTCTCGGTTGGATTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCATATTTTTGAATTGCCCATGTCCTTTTTTGCCACAAGGCGGACAGGTGAAGTTATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATGCCAATCTTTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGTGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTGATTTTA
AACGTCGTCATTCTCTGGTATGGTTCACGTTTAGTCATGTCTGGGAACATTTCAGTAGGTCAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACACCAATGGAAAATATTATTAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAACA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTGATGGCAGACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTCTTTGATAATGTTTCTTATAAATATGGTTTTGGTCGTGACACACTGAGTCATGTGAATTTACACATTAAGAA
GGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGTTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGCCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACGATTTTAGAAAATTTAACTTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATCGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGTTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
GACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACAAGTTA
TCGAAGAAGGGCATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(166-436)

Peptidase C39 family (Peptidase_C39)

(3-140)

ABC transporter (ABC_tran)

(498-647)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.266

99.72

0.701
  comA Streptococcus mitis NCTC 12261

66.62

99.301

0.662
  comA Streptococcus pneumoniae D39

66.102

99.021

0.655
  comA Streptococcus pneumoniae R6

66.102

99.021

0.655
  comA Streptococcus pneumoniae Rx1

66.102

99.021

0.655
  comA Streptococcus mitis SK321

65.915

99.301

0.655
  comA Streptococcus gordonii str. Challis substr. CH1

65.498

99.72

0.653
  comA Streptococcus pneumoniae TIGR4

65.819

99.021

0.652

Multiple sequence alignment