Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQN21_RS06340 Genome accession   NZ_LS483409
Coordinates   1248684..1250024 (-) Length   446 a.a.
NCBI ID   WP_009854246.1    Uniprot ID   A0A139QTN8
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1243684..1255024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS06315 (NCTC13773_01281) - 1244177..1245241 (-) 1065 WP_009854242.1 BMP family lipoprotein -
  DQN21_RS06320 (NCTC13773_01282) deoC 1245442..1246104 (-) 663 WP_074580979.1 deoxyribose-phosphate aldolase -
  DQN21_RS06325 (NCTC13773_01283) - 1246595..1247188 (-) 594 WP_012961986.1 class I SAM-dependent methyltransferase -
  DQN21_RS06330 (NCTC13773_01284) coaA 1247302..1248222 (+) 921 WP_009854245.1 type I pantothenate kinase -
  DQN21_RS06335 (NCTC13773_01285) rpsT 1248297..1248548 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  DQN21_RS06340 (NCTC13773_01286) ciaH 1248684..1250024 (-) 1341 WP_009854246.1 sensor histidine kinase Regulator
  DQN21_RS06345 (NCTC13773_01287) ciaR 1250014..1250688 (-) 675 WP_009854247.1 response regulator transcription factor Regulator
  DQN21_RS06350 (NCTC13773_01288) - 1250886..1253429 (-) 2544 WP_077496889.1 M1 family metallopeptidase -
  DQN21_RS06355 (NCTC13773_01289) phoU 1253652..1254305 (-) 654 WP_009854249.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50097.86 Da        Isoelectric Point: 5.3673

>NTDB_id=1140564 DQN21_RS06340 WP_009854246.1 1248684..1250024(-) (ciaH) [Streptococcus gallolyticus strain NCTC13773]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNANDYVVRTMERSDTLQSDDSSTD
TFSGGTSSSGKAKPSTGGVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEDSVGEIKEQKITTIFGQTEKYHVLTV
KVSSSEYPSIKYATFLVSVRQLDEASERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKSFVENASHELRTP
LAVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPTTFNEIFENYDMIAEENG
KTFVGHNLAERPIKSDRTLLKQLMTILFDNAIKYTDDDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1140564 DQN21_RS06340 WP_009854246.1 1248684..1250024(-) (ciaH) [Streptococcus gallolyticus strain NCTC13773]
ATGCTGAATAAATTACAGAAAAAATTATCGTCAGGGACATTTTCACATTTCTTCCATTTCTTTGCTGTCTTTACGGGAAT
TTTTGTCATCATGACAGTTATCATTTTGCAGATTATGCGCTATGGTCTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCCAATGATTATGTCGTGCGAACTATGGAACGTAGCGATACTTTGCAATCGGATGATTCTTCTACGGAC
ACTTTTTCAGGAGGAACAAGTAGTTCTGGGAAAGCGAAACCTAGTACTGGCGGAGTTGGTCTAAGTAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATCTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACGTTATCGACAACTTTTGATG
AAGATAGTGTCGGCGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATACCATGTGCTGACTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATATGCTACTTTCCTTGTTAGCGTTCGTCAGTTAGATGAAGCTAGCGA
ACGATATGTAACAATTACGATCACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAATCCTTTGTCGAAAACGCTAGTCATGAGTTGCGTACACCG
CTTGCTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCTGATGCTACAATTTTGGATAATAGTGAAAGTATTGC
CGCCAGTCTAGACGAAGTTCGAAATATGCGAATTTTGACCACAAATCTGCTGAATTTGGCACGTCGTGACGATGGTTTGA
AAGTTGAGTTGGAGGATATTCAACCAACGACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACATTTGTCGGACATAATTTGGCAGAGCGACCAATCAAATCAGATCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATACACCGACGATGATGGTGTCATTGAATTTACCGTTAAAACAACAGACAAACAAACAATTC
TGACAGTTGCTGATAACGGCCCAGGGATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGTGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGACGTTTTAAAAGGCGATAT
TCAAGTCAAAGACAACCAACCAAAAGGAACTATTTTTGAAGTTCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139QTN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.368

99.327

0.59
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511

Multiple sequence alignment