Detailed information NTG1140558

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQN21_RS03985
• Genome accession: NZ_LS483409
• Coordinates: 729499..731730 (+)
• Length: 743 a.a.
• NCBI ID: WP_077496502.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus strain NCTC13773
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 724499..736730

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN21_RS03960 (NCTC13773_00797)	-	725260..726840 (+)	1581	WP_077496496.1	DEAD/DEAH box helicase	-
DQN21_RS03965 (NCTC13773_00798)	-	726884..727156 (-)	273	WP_009853764.1	GIY-YIG nuclease family protein	-
DQN21_RS03970 (NCTC13773_00799)	-	727131..727892 (-)	762	WP_077496498.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
DQN21_RS03975 (NCTC13773_00800)	-	728000..728746 (+)	747	WP_009853766.1	lysophospholipid acyltransferase family protein	-
DQN21_RS03980 (NCTC13773_00801)	comEA	728841..729506 (+)	666	WP_077496500.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQN21_RS03985 (NCTC13773_00802)	comEC/celB	729499..731730 (+)	2232	WP_077496502.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQN21_RS03990 (NCTC13773_00803)	holA	731804..732841 (+)	1038	WP_077498002.1	DNA polymerase III subunit delta	-
DQN21_RS03995 (NCTC13773_00804)	sodA	732930..733538 (+)	609	WP_061458979.1	superoxide dismutase SodA	-
DQN21_RS04000 (NCTC13773_00805)	-	733690..734415 (+)	726	WP_077496504.1	YebC/PmpR family DNA-binding transcriptional regulator	-
DQN21_RS04005 (NCTC13773_00806)	queA	734447..735475 (-)	1029	WP_077496506.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
DQN21_RS04010 (NCTC13773_00807)	-	735651..736151 (+)	501	WP_012961668.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83738.04 Da
• Isoelectric Point: 8.5001

>NTDB_id=1140558 DQN21_RS03985 WP_077496502.1 729499..731730(+) (comEC/celB) [Streptococcus gallolyticus strain NCTC13773]
MIKYFPIKPIQLAFLLTLLYYFCFSKVIGCLMFLLLALVFLWQQYGWKAWCQVCLCLTCFAVFFLTKSNQTEQAYQAAPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTVVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVHKMTLWEKLHDVRRKAIVSIQQHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTTGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSIIF
ILSPLVKLTCFNGCFVFLETVIKNTKAILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVGLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVRVVTAGDVLPIMGSHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=1140558 DQN21_RS03985 WP_077496502.1 729499..731730(+) (comEC/celB) [Streptococcus gallolyticus strain NCTC13773]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTACTCACTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GTTTGTGTTTAACCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGCAGCGCCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCTGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGGTTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACCTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTCATAAGATGACTTTGTGGGAGAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCAACATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTCGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATCCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTTTTCTGTTTCGGTGATTCGGAGTTTAATTCAGT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTAGCTTTAACTTTGTTTGTTCTTTTCATAGTTATGCCAAAT
TTTCTGCTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCAATCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGAACACTAAGGC
AATTTTGGGCGGTCCGATTGTTTTTGGTAAACCAAGTCTTGGTATCTTGGTGCTGCTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGGTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGTTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAAGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTATTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGATAGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGACATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCACCAAGAAACGCTTGAACGCTTCCGAGCTCAAAACATGACCATT
TACCGCACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-459)

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.83	99.865	0.528
comEC/celB	Streptococcus mitis SK321	52.291	99.865	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.279	100	0.513
comEC/celB	Streptococcus pneumoniae Rx1	50.74	100	0.507
comEC/celB	Streptococcus pneumoniae D39	50.74	100	0.507
comEC/celB	Streptococcus pneumoniae R6	50.74	100	0.507
comEC	Lactococcus lactis subsp. cremoris KW2	47.779	100	0.478