Detailed information NTG1140366

Bioinformatically predicted

Overview

• Name: comD/comD2
• Type: Regulator
• Locus tag: DQN23_RS07960
• Genome accession: NZ_LS483403
• Coordinates: 1583272..1584105 (-)
• Length: 277 a.a.
• NCBI ID: WP_111713004.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC13774
• Function: phosphorylation of ComE (predicted from homology) Competence regulation

Genomic Context

Location: 1578272..1589105

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN23_RS07935 (NCTC13774_01664)	-	1579499..1580131 (-)	633	WP_020917486.1	thiamine diphosphokinase	-
DQN23_RS07940 (NCTC13774_01665)	rpe	1580124..1580786 (-)	663	WP_020917487.1	ribulose-phosphate 3-epimerase	-
DQN23_RS07945 (NCTC13774_01666)	rsgA	1580793..1581665 (-)	873	WP_058832824.1	ribosome small subunit-dependent GTPase A	-
DQN23_RS09535	comE/comE2	1581983..1582144 (-)	162	WP_313769791.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	Regulator
DQN23_RS09540 (NCTC13774_01668)	comE/comE2	1582122..1582502 (-)	381	WP_267895290.1	LytTR family DNA-binding domain-containing protein	Regulator
DQN23_RS09435 (NCTC13774_01669)	comE/comE2	1582487..1582714 (-)	228	WP_233422877.1	hypothetical protein	Regulator
DQN23_RS07960 (NCTC13774_01670)	comD/comD2	1583272..1584105 (-)	834	WP_111713004.1	sensor histidine kinase	Regulator
DQN23_RS07965 (NCTC13774_01671)	-	1585001..1585294 (-)	294	WP_020917489.1	bacteriocin immunity protein	-
DQN23_RS07970 (NCTC13774_01672)	-	1585322..1585627 (-)	306	WP_020917490.1	bacteriocin immunity protein	-
DQN23_RS07975	-	1585640..1585789 (-)	150	WP_020917491.1	hypothetical protein	-
DQN23_RS07980 (NCTC13774_01673)	rsmA	1586196..1587068 (-)	873	WP_021143191.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
DQN23_RS07985 (NCTC13774_01674)	rnmV	1587191..1587760 (-)	570	WP_167394768.1	ribonuclease M5	-
DQN23_RS07990 (NCTC13774_01675)	-	1587753..1588523 (-)	771	WP_003066600.1	TatD family hydrolase	-

Sequence

Protein

• Length: 277 a.a.
• Molecular weight: 31707.21 Da
• Isoelectric Point: 4.6102

>NTDB_id=1140366 DQN23_RS07960 WP_111713004.1 1583272..1584105(-) (comD/comD2) [Streptococcus lutetiensis strain NCTC13774]
MVSYFLFMDAVAIVKPFHNTVNDAIRGIVAFIYLILLFVFLFYLNFRHGQEQKNELLRNQEMELAALENCSKHVESLYQE
VRSFRHDYANVLMSLKVGIDQGNLDDIKKIYNEITANSTKLVKNNKFDLTRLANIIDSGVKSFMSAKFLQAENQGIAISL
EVAEKMENPSMPLIYYIRILSILFDNAIEAALESETPEISVANFYQDGNFVFMIENSTKEKSVDLTKIFERGYSTKGENR
GLGLATLMDFQDDDENLSVEIRSSDYTFTQVVRIFDA

Nucleotide

• Length: 834 bp

>NTDB_id=1140366 DQN23_RS07960 WP_111713004.1 1583272..1584105(-) (comD/comD2) [Streptococcus lutetiensis strain NCTC13774]
ATGGTCTCTTATTTTTTATTCATGGATGCCGTTGCTATTGTAAAACCTTTTCATAATACTGTTAACGATGCAATAAGGGG
AATTGTTGCTTTCATTTATCTCATCCTTCTTTTTGTCTTCCTCTTTTATCTTAATTTCCGTCATGGGCAAGAGCAGAAAA
ATGAATTGCTTCGTAACCAGGAAATGGAATTGGCGGCCTTGGAAAATTGTAGCAAGCACGTGGAGAGTTTGTATCAGGAG
GTTCGCAGTTTCAGGCATGACTACGCTAATGTCCTGATGAGTTTAAAGGTTGGAATTGATCAAGGCAATCTTGATGACAT
CAAGAAAATTTACAACGAAATCACAGCCAATTCGACGAAGCTAGTCAAGAATAATAAATTTGACCTGACTCGCTTGGCTA
ACATCATAGACAGCGGCGTCAAAAGCTTCATGTCAGCTAAATTTTTGCAAGCTGAAAATCAAGGGATTGCAATTAGTCTA
GAAGTCGCCGAAAAAATGGAAAATCCTAGCATGCCATTAATTTATTACATTCGAATTTTGTCGATTCTGTTTGATAATGC
CATAGAAGCCGCTTTGGAGTCAGAAACTCCAGAAATCTCAGTCGCTAATTTTTACCAAGATGGTAACTTTGTTTTCATGA
TTGAGAATTCAACTAAGGAAAAATCAGTGGATTTAACTAAGATTTTTGAGCGTGGCTACTCAACTAAGGGAGAAAATCGT
GGACTTGGTCTAGCCACACTAATGGATTTCCAAGATGACGACGAAAATCTGTCAGTTGAAATTCGCAGCTCAGATTACAC
ATTTACACAAGTTGTCCGAATTTTTGATGCATAA

Domains

Predicted by InterproScan.

• GHKL domain (HATPase_c_5) (177-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/comD2	Streptococcus equinus JB1	88.087	100	0.881
comD/comD3	Streptococcus equinus JB1	83.026	97.834	0.812
comD/blpH	Streptococcus mutans UA159	39.051	98.917	0.386
comD/comD1	Streptococcus equinus JB1	46.32	83.394	0.386