Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQN23_RS01585 Genome accession   NZ_LS483403
Coordinates   280611..281372 (+) Length   253 a.a.
NCBI ID   WP_111712618.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC13774     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 275611..286372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN23_RS01570 (NCTC13774_00317) - 276016..277587 (-) 1572 WP_020916165.1 ABC transporter permease subunit -
  DQN23_RS01575 (NCTC13774_00318) - 277724..279616 (+) 1893 WP_171009916.1 DUF2207 domain-containing protein -
  DQN23_RS01580 (NCTC13774_00319) - 279668..280507 (+) 840 WP_020916167.1 undecaprenyl-diphosphate phosphatase -
  DQN23_RS01585 (NCTC13774_00320) mecA 280611..281372 (+) 762 WP_111712618.1 adaptor protein MecA Regulator
  DQN23_RS01590 (NCTC13774_00321) - 281374..282537 (+) 1164 WP_058833246.1 glycosyltransferase family 4 protein -
  DQN23_RS01595 (NCTC13774_00322) sufC 282652..283422 (+) 771 WP_111712619.1 Fe-S cluster assembly ATPase SufC -
  DQN23_RS01600 (NCTC13774_00323) sufD 283497..284759 (+) 1263 WP_111712620.1 Fe-S cluster assembly protein SufD -
  DQN23_RS01605 (NCTC13774_00324) - 284761..285993 (+) 1233 WP_058833245.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29172.99 Da        Isoelectric Point: 4.0425

>NTDB_id=1140333 DQN23_RS01585 WP_111712618.1 280611..281372(+) (mecA) [Streptococcus lutetiensis strain NCTC13774]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKDIKFEDLAAFDDVSNMSPEEFFKTLEQTMLSKDDTEAHEKLGKIEEMMEGAVEDVLTEHAQQAEIEPEEDVNPSDYVH
YVLDFPSLEAAVAFAKVIDFPVEASELYKMDGAYYMTVLIDLQNHPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVEKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1140333 DQN23_RS01585 WP_111712618.1 280611..281372(+) (mecA) [Streptococcus lutetiensis strain NCTC13774]
ATGGAAATGAAACAGATTAGCGAGACAACGCTCAAAATAACGATTAGTATGGAAGATTTGGAAGAACGCGGAATGGAGTT
GAAAGACTTCTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAATTGGATTTACCAGATAATT
TCAAAGACAGTGGCATGCTAAGTTTCCGTGTGACACCACGTAAAGACCGTATTGATGTCTTTGTTACCAAATCTGAAATC
AATAAAGATATAAAGTTTGAAGATTTAGCAGCTTTTGATGATGTTTCAAACATGTCACCTGAGGAATTTTTCAAGACTTT
AGAGCAGACAATGTTGTCTAAAGACGACACGGAAGCTCACGAAAAATTAGGTAAGATTGAAGAAATGATGGAAGGTGCTG
TTGAAGATGTTCTGACAGAACATGCCCAACAAGCTGAGATTGAACCGGAAGAAGATGTGAATCCATCAGATTATGTTCAC
TATGTCTTGGATTTTCCAAGCTTAGAAGCTGCTGTTGCTTTTGCTAAGGTTATTGATTTTCCAGTTGAAGCTTCAGAGCT
TTATAAGATGGATGGGGCTTACTACATGACAGTTCTCATTGATTTGCAAAATCATCCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACGCGTGCTTATTTACAAGAGCATGCGGTTGAATTATTGACG
GATGATGCCGTCGAAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.8

98.814

0.66
  mecA Streptococcus thermophilus LMD-9

58.635

98.419

0.577
  mecA Streptococcus thermophilus LMG 18311

57.831

98.419

0.569
  mecA Streptococcus pneumoniae Rx1

49.412

100

0.498
  mecA Streptococcus pneumoniae D39

49.412

100

0.498
  mecA Streptococcus pneumoniae R6

49.412

100

0.498
  mecA Streptococcus pneumoniae TIGR4

49.412

100

0.498

Multiple sequence alignment