Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   DQM95_RS09990 Genome accession   NZ_LS483397
Coordinates   1973311..1974513 (+) Length   400 a.a.
NCBI ID   WP_238989846.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC3858     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1968311..1979513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM95_RS09965 (NCTC3858_02024) - 1969541..1972111 (+) 2571 WP_037593163.1 YfhO family protein -
  DQM95_RS09985 (NCTC3858_02028) rlmH 1972646..1973125 (-) 480 WP_037593045.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQM95_RS09990 (NCTC3858_02029) htrA 1973311..1974513 (+) 1203 WP_238989846.1 S1C family serine protease Regulator
  DQM95_RS09995 (NCTC3858_02030) spo0J 1974591..1975367 (+) 777 WP_015912154.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42530.07 Da        Isoelectric Point: 5.1117

>NTDB_id=1140189 DQM95_RS09990 WP_238989846.1 1973311..1974513(+) (htrA) [Streptococcus uberis strain NCTC3858]
MPVSKFKHFFKYIMIVGLGFIGGALAFFVMNLLPHPSSTTNLNNPTTTSKVTYKNTTNTTKAVKVIQDAVVSVVNYQKND
SLNSAMDIFSQGDSSTKENDGLSIYSEGSGVIYKKDGDSAYLVTNNHVIDKAERIEIVLADGSKVVGKLIGADTYSDLAV
VKISSDKIKTVAQFADSSKINIGEVAIAIGSPLGTEYANSVTEGIVSSLSRTVTLKNEEGQTVSTNAIQTDAAINPGNSG
GPLINIEGQIIGINSSKISQSKSSGNAVEGMGFAIPANDVIKIINQLESKGEVVRPALGISMVNLSDLSTNALDQLKVPK
NVTSGIVVAKVVDNMPASGKLEQYDIITEIDGEEVSSTSDLQSILYGHDINDTVKVTFYRGNDKKSTTIELTKTTKDLEK

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=1140189 DQM95_RS09990 WP_238989846.1 1973311..1974513(+) (htrA) [Streptococcus uberis strain NCTC3858]
ATGCCTGTGTCTAAGTTTAAACATTTTTTCAAATACATAATGATAGTCGGATTAGGCTTCATTGGTGGTGCTTTAGCATT
CTTTGTGATGAATCTGTTACCACATCCATCATCCACAACAAATCTTAATAACCCAACGACGACAAGTAAAGTAACCTATA
AAAATACTACTAATACGACTAAAGCTGTTAAAGTGATTCAAGATGCAGTTGTTTCTGTAGTTAACTATCAAAAAAATGAT
TCTTTAAACTCAGCCATGGATATTTTTAGTCAAGGTGATTCATCAACTAAAGAGAATGATGGACTTTCTATTTATAGTGA
AGGATCAGGTGTTATATACAAAAAAGATGGTGATTCTGCATATCTGGTAACCAACAACCACGTAATAGACAAAGCTGAAA
GAATTGAAATTGTTTTAGCTGATGGTTCAAAAGTTGTTGGGAAATTAATTGGTGCTGACACTTATTCTGACTTGGCTGTT
GTAAAAATTTCTTCAGACAAAATTAAGACTGTAGCTCAGTTTGCAGATTCTTCCAAAATAAACATAGGTGAAGTTGCAAT
TGCAATTGGTAGTCCTCTTGGAACAGAATATGCTAATTCCGTAACTGAAGGAATTGTTTCAAGTTTAAGTAGAACAGTAA
CTTTAAAAAATGAAGAAGGACAAACTGTTTCAACTAATGCCATTCAAACAGATGCTGCTATTAACCCTGGAAACTCTGGC
GGACCTTTAATTAATATTGAAGGACAAATTATTGGAATAAACTCTAGCAAAATCTCACAGTCTAAATCATCTGGAAATGC
AGTCGAAGGAATGGGATTTGCAATTCCAGCTAATGACGTTATTAAAATTATTAACCAACTTGAAAGCAAAGGCGAAGTAG
TTCGACCTGCATTAGGTATTTCAATGGTTAATCTAAGTGATTTATCAACAAATGCCCTTGATCAGCTCAAAGTTCCAAAA
AATGTTACTAGTGGTATCGTAGTTGCTAAAGTCGTAGACAATATGCCTGCCTCAGGAAAACTTGAACAATATGATATTAT
CACTGAAATTGATGGGGAAGAAGTGAGCAGTACAAGTGATTTACAAAGTATTCTGTATGGGCATGACATTAATGATACCG
TAAAAGTCACTTTTTATAGAGGTAATGATAAGAAATCTACTACTATTGAATTAACTAAAACTACCAAAGATTTAGAAAAA
TAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-391)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

63.038

98.75

0.623
  htrA Streptococcus pneumoniae Rx1

56.091

98.5

0.552
  htrA Streptococcus pneumoniae D39

56.091

98.5

0.552
  htrA Streptococcus gordonii str. Challis substr. CH1

56.091

98.5

0.552
  htrA Streptococcus pneumoniae R6

56.091

98.5

0.552
  htrA Streptococcus pneumoniae TIGR4

56.091

98.5

0.552
  htrA Streptococcus mitis NCTC 12261

55.838

98.5

0.55

Multiple sequence alignment