Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   DQM95_RS07655 Genome accession   NZ_LS483397
Coordinates   1489275..1491161 (-) Length   628 a.a.
NCBI ID   WP_037593427.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC3858     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1484275..1496161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM95_RS07630 (NCTC3858_01554) - 1485037..1485393 (-) 357 WP_015911700.1 S1 RNA-binding domain-containing protein -
  DQM95_RS07635 (NCTC3858_01555) - 1485393..1486793 (-) 1401 WP_037593423.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM95_RS07640 (NCTC3858_01556) - 1486827..1487468 (-) 642 WP_015911702.1 response regulator transcription factor -
  DQM95_RS07645 (NCTC3858_01557) - 1487461..1488465 (-) 1005 WP_037593424.1 sensor histidine kinase -
  DQM95_RS07650 (NCTC3858_01558) liaF 1488462..1489157 (-) 696 WP_037593426.1 cell wall-active antibiotics response protein LiaF -
  DQM95_RS07655 (NCTC3858_01559) pknB 1489275..1491161 (-) 1887 WP_037593427.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQM95_RS07660 (NCTC3858_01560) - 1491158..1491898 (-) 741 WP_015911706.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQM95_RS07665 (NCTC3858_01561) rsmB 1491936..1493258 (-) 1323 WP_037593430.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQM95_RS07670 (NCTC3858_01562) fmt 1493248..1494183 (-) 936 WP_015911708.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 628 a.a.        Molecular weight: 68257.37 Da        Isoelectric Point: 8.9129

>NTDB_id=1140176 DQM95_RS07655 WP_037593427.1 1489275..1491161(-) (pknB) [Streptococcus uberis strain NCTC3858]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLYEMLTGHIPYDGDSAVTIALQHFQKPLPSILDENKMVP
QALENVVIKATAKKLSDRYASTFDMSRDLMTALSYNRSREKKLVFEDGDSTKPLPKVSPTPNVTPKSSPTVSATKANEPA
KQDYLQKPQKERKRGRFLGTLFKILFALFVVGVAIFTFLILTKPSTVKVPNLNGSTLSVAKAELKTMGFKVGDIKKIESG
TVAVGHVVKTDPSAGTAKREGATIDIFVSSGKKGFVMEDYTGQNYQDVISNLMTTYGVSRSKIKIKRINTNDYQADTVIS
QTPDKGEKFNPDGKSKITLSVASSGTVTMPDLTGYTYQEALNELTALGINTNRIKTYYTNGSSGEKKSMIVSEQTPYAYS
SISLSDSSEISLGLYAATETSNSSTPSSSSEVSSSSSSSTYDSGISSETTPSSSSSSTNAGLDPNHNP

Nucleotide


Download         Length: 1887 bp        

>NTDB_id=1140176 DQM95_RS07655 WP_037593427.1 1489275..1491161(-) (pknB) [Streptococcus uberis strain NCTC3858]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAATGACTTGATATTAGATAATGAGGACGTAGCTATTAAGGTATTACGTACAAATTATCAAACAGATCAGGTTG
CAGTTGCACGTTTTCAACGAGAAGCGCGTGCGATGGCAGAATTAAATCATCCGAACATTGTAGCCATACGAGATATAGGT
GAAGAAGACGGACAGCAGTTTTTAGTAATGGAATACGTCGATGGTGCAGACTTGAAAAAATACATTCAAGATCATGCTCC
ATTGTCTAACAACGAAGTTGTTAGAATTATGGAGGAAGTTCTCTCTGCAATGACACTTGCTCACCAAAAGGGCATTGTTC
ATAGGGACTTAAAACCTCAAAATATTTTATTAACCAAATCTGGAGTCGTTAAAGTAACTGATTTTGGTATAGCTGTTGCA
TTTGCTGAAACGAGTTTAACCCAAACAAACTCCATGTTAGGAAGTGTGCATTATTTATCTCCAGAACAAGCTCGTGGCTC
AAAAGCGACTATTCAGAGCGATATATATGCAATGGGTATCATGCTTTATGAAATGTTGACTGGACATATTCCATATGATG
GAGATAGTGCAGTTACCATTGCTTTACAACATTTCCAAAAACCATTACCATCTATTTTAGATGAAAATAAAATGGTGCCA
CAAGCTTTGGAAAATGTGGTCATAAAAGCTACAGCTAAGAAGCTAAGTGATCGCTATGCTTCGACATTTGACATGAGCAG
GGATTTAATGACGGCTCTAAGCTATAATAGAAGCCGTGAGAAAAAATTAGTGTTTGAGGATGGCGACAGTACAAAGCCAT
TACCAAAAGTTTCTCCAACACCAAATGTAACCCCTAAATCATCTCCAACAGTTTCAGCAACTAAGGCAAATGAGCCTGCA
AAACAAGACTACTTGCAAAAACCACAAAAAGAGAGAAAACGAGGTCGTTTTTTAGGCACTTTATTCAAAATTCTCTTTGC
CCTCTTTGTCGTAGGTGTGGCAATCTTTACCTTCCTTATTTTGACGAAACCATCAACGGTCAAAGTTCCTAATTTAAATG
GTTCAACTTTATCTGTCGCTAAAGCTGAATTGAAAACAATGGGATTTAAAGTTGGAGATATCAAAAAAATAGAAAGTGGA
ACTGTTGCGGTAGGTCATGTTGTTAAAACAGATCCTAGTGCTGGTACAGCAAAACGTGAAGGAGCCACTATTGATATATT
TGTATCATCAGGGAAAAAAGGTTTTGTCATGGAAGATTACACAGGACAAAATTACCAAGATGTTATTTCTAATCTGATGA
CTACTTATGGTGTTTCTCGTTCTAAAATCAAAATTAAACGAATCAACACAAATGACTATCAAGCAGATACAGTTATTAGC
CAAACGCCGGATAAAGGTGAAAAATTCAATCCGGATGGTAAGTCAAAAATTACCTTAAGTGTGGCATCAAGTGGAACTGT
TACAATGCCAGATTTAACAGGATATACTTACCAAGAAGCATTAAACGAATTGACTGCTTTAGGCATTAACACAAACCGGA
TCAAGACTTACTATACTAATGGTTCAAGTGGTGAAAAGAAATCCATGATTGTCTCAGAGCAAACCCCTTACGCTTATTCA
AGCATTTCTCTTTCTGATTCTAGTGAAATTAGTTTAGGATTATATGCCGCTACAGAAACGTCGAACAGCTCAACACCATC
AAGTTCAAGTGAAGTTTCATCTTCTAGTAGTTCATCGACATATGATTCAGGAATTTCTTCAGAAACAACACCATCAAGTT
CTTCTTCTTCGACAAATGCGGGACTTGATCCAAATCACAATCCATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-253)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(507-572)

PASTA domain (PASTA)

(436-502)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.753

92.994

0.611
  stkP/pknB Streptococcus salivarius strain HSISS4

62.566

90.605

0.567
  stkP Streptococcus pneumoniae TIGR4

53.589

95.382

0.511
  stkP Streptococcus pneumoniae D39

53.422

95.382

0.51
  stkP Streptococcus pneumoniae R6

53.422

95.382

0.51
  stkP Streptococcus pneumoniae Rx1

53.255

95.382

0.508

Multiple sequence alignment