Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQM95_RS05245 Genome accession   NZ_LS483397
Coordinates   984189..985499 (-) Length   436 a.a.
NCBI ID   WP_037592122.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC3858     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 979189..990499
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM95_RS05215 (NCTC3858_01067) - 979713..980099 (-) 387 WP_307935650.1 cytidine deaminase -
  DQM95_RS05220 (NCTC3858_01068) deoC 980089..980751 (-) 663 WP_012658451.1 deoxyribose-phosphate aldolase -
  DQM95_RS05225 (NCTC3858_01069) - 980762..982039 (-) 1278 WP_012658452.1 pyrimidine-nucleoside phosphorylase -
  DQM95_RS05230 (NCTC3858_01070) - 982036..982626 (-) 591 WP_012658453.1 class I SAM-dependent methyltransferase -
  DQM95_RS05235 (NCTC3858_01071) coaA 982890..983810 (+) 921 WP_037592124.1 type I pantothenate kinase -
  DQM95_RS05240 (NCTC3858_01072) rpsT 983870..984112 (+) 243 WP_160463058.1 30S ribosomal protein S20 -
  DQM95_RS05245 (NCTC3858_01073) ciaH 984189..985499 (-) 1311 WP_037592122.1 cell wall metabolism sensor histidine kinase WalK Regulator
  DQM95_RS05250 (NCTC3858_01074) ciaR 985492..986166 (-) 675 WP_012658457.1 response regulator transcription factor Regulator
  DQM95_RS05255 (NCTC3858_01075) - 986288..988825 (-) 2538 WP_037592121.1 M1 family metallopeptidase -
  DQM95_RS05260 (NCTC3858_01076) phoU 988896..989549 (-) 654 WP_012658459.1 phosphate signaling complex protein PhoU -
  DQM95_RS05265 (NCTC3858_01077) pstB 989569..990327 (-) 759 WP_012658460.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 50104.14 Da        Isoelectric Point: 7.6210

>NTDB_id=1140168 DQM95_RS05245 WP_037592122.1 984189..985499(-) (ciaH) [Streptococcus uberis strain NCTC3858]
MTKYKELLKSDNFNHFSHYFSVFTGIFAVMTFIILQIMKFGVYSSVDSSLLTVAKNSENYTNKTMERISSFYFDNQSGHF
KASTEAFKIKNDNEPVANTDILLFSSNGIVINSFDALSNFQNFTLNKNELNTIQTQKLVNYYGHEEKFHTITVRVHSKNY
PAIAYMMAVVNVEQSEKTNERYEKFIIIVMIVFWLISIIASIYLANWSSKPIIESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNESILDNSEAIASSLDEVRNMRILTTNLLNLARRDDGIKPDWEEIDAQFFNSIFENYSLIAEENGKSFQFDN
QVHRKVKTDKALLKQLLTILFDNAIKYTDADGEIEIQVSTGDKHLYLTVLDNGPGINDIDKKKIFDRFYRVDKARTRSKG
GFGLGLALAQQIVQSLKGSIVVKDNRPKGTIFEVKF

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1140168 DQM95_RS05245 WP_037592122.1 984189..985499(-) (ciaH) [Streptococcus uberis strain NCTC3858]
ATGACTAAATATAAAGAATTACTTAAATCCGATAATTTCAATCACTTTTCCCATTATTTTTCTGTATTTACGGGCATTTT
TGCGGTTATGACTTTCATTATCCTTCAGATTATGAAATTTGGTGTCTATTCATCTGTTGATAGTAGTTTATTGACAGTTG
CCAAGAATTCAGAGAATTATACCAATAAGACCATGGAGAGGATTTCTTCCTTTTATTTTGATAACCAAAGTGGTCATTTT
AAAGCTAGTACAGAAGCATTTAAAATAAAGAATGATAATGAGCCGGTTGCAAATACAGATATCTTACTCTTTAGTTCAAA
CGGTATTGTTATCAACAGTTTTGATGCGCTTTCCAATTTTCAAAATTTTACGCTGAATAAAAACGAATTAAATACGATTC
AAACGCAAAAATTAGTCAATTACTATGGCCATGAAGAAAAATTTCATACCATTACAGTAAGGGTACATTCCAAAAACTAC
CCTGCAATCGCCTATATGATGGCCGTAGTAAATGTTGAACAGTCAGAAAAAACAAATGAACGATATGAGAAATTTATCAT
AATCGTTATGATTGTGTTCTGGCTCATTTCCATTATTGCTAGTATATATCTGGCAAATTGGAGTAGTAAGCCTATCATTG
AGAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCCAGTCATGAATTAAGGACGCCTTTGGCCGTTTTACAGAATCGT
TTAGAAAGTTTATTTCGAAAGCCAAATGAGAGTATTCTTGATAATAGCGAAGCCATTGCGTCAAGCTTAGATGAAGTCAG
AAATATGAGAATACTAACCACTAATCTTCTTAATCTTGCGAGACGTGACGATGGTATAAAACCCGACTGGGAAGAAATTG
ATGCTCAATTCTTTAATAGTATTTTTGAAAATTATAGCCTTATTGCAGAAGAAAATGGCAAATCATTCCAGTTTGATAAT
CAAGTTCATAGAAAAGTAAAAACTGATAAAGCTCTACTCAAACAATTGTTAACGATTCTTTTTGACAATGCCATAAAATA
TACTGATGCTGACGGTGAGATTGAAATACAGGTTTCAACTGGGGATAAACATCTCTATCTTACTGTCTTAGATAATGGAC
CTGGCATTAATGATATTGACAAAAAGAAAATTTTTGACAGATTCTATAGAGTCGATAAAGCCAGAACAAGAAGTAAGGGT
GGATTTGGATTAGGATTAGCCTTAGCTCAACAAATCGTTCAATCTTTAAAAGGAAGTATTGTCGTTAAGGATAATAGGCC
TAAAGGGACAATTTTTGAAGTCAAATTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.881

100

0.569
  ciaH Streptococcus pneumoniae Rx1

50.575

99.771

0.505
  ciaH Streptococcus pneumoniae D39

50.575

99.771

0.505
  ciaH Streptococcus pneumoniae R6

50.575

99.771

0.505
  ciaH Streptococcus pneumoniae TIGR4

50.575

99.771

0.505

Multiple sequence alignment