Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   N506_RS04595 Genome accession   NZ_CP006803
Coordinates   931220..933379 (-) Length   719 a.a.
NCBI ID   WP_095669894.1    Uniprot ID   -
Organism   Lactobacillus gasseri DSM 14869     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 926220..938379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N506_RS04550 (N506_0934) - 927546..927824 (-) 279 WP_095669887.1 hypothetical protein -
  N506_RS04560 (N506_0935) - 928274..928672 (-) 399 WP_095669888.1 hypothetical protein -
  N506_RS04575 (N506_0936) - 929096..929377 (-) 282 WP_095669890.1 hypothetical protein -
  N506_RS04580 (N506_0938) - 929780..930013 (-) 234 WP_095669891.1 hypothetical protein -
  N506_RS04585 (N506_0939) - 930282..930566 (-) 285 WP_095669892.1 bacteriocin immunity protein -
  N506_RS04590 (N506_0940) - 930616..931209 (-) 594 WP_095669893.1 HlyD family efflux transporter periplasmic adaptor subunit -
  N506_RS04595 (N506_0941) comA 931220..933379 (-) 2160 WP_095669894.1 peptide cleavage/export ABC transporter Regulator
  N506_RS04600 - 933392..934189 (-) 798 Protein_893 LytR/AlgR family response regulator transcription factor -
  N506_RS04605 (N506_0944) - 934186..935517 (-) 1332 WP_095669895.1 GHKL domain-containing protein -
  N506_RS04610 (N506_0945) - 935518..935670 (-) 153 WP_095669896.1 lactacin F inducer peptide precursor -
  N506_RS04615 (N506_0946) - 935811..937178 (-) 1368 WP_095669897.1 MFS transporter -
  N506_RS04620 (N506_0947) udk 937340..937975 (+) 636 WP_186433583.1 uridine kinase -

Sequence

Protein


Download         Length: 719 a.a.        Molecular weight: 80913.31 Da        Isoelectric Point: 8.3332

>NTDB_id=114016 N506_RS04595 WP_095669894.1 931220..933379(-) (comA) [Lactobacillus gasseri DSM 14869]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENS
IQYPFIVHVLKQGELLHYYVVLKNAKNYLVIADPDPSVGVIKMPKDRFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNILGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPVYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFIQ
LSLNVIVLWVGAKVVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNRLNEVYQVKSEFDKKTMVNNPAL
LEGTISYDKVDYRYGYGADVLKDINLKISQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEINKHTLRSY
VNYVPQTPYIFSGTVKENLLLGSRPDITEEDVIKACQIAGIDQEITNLPLQFETKLDEKAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKKVVDNLMKLKDKTIIFIAHRLAIAERADKVIVIDHGQIVEEGSHSELMSKPGFYYDLVKG

Nucleotide


Download         Length: 2160 bp        

>NTDB_id=114016 N506_RS04595 WP_095669894.1 931220..933379(-) (comA) [Lactobacillus gasseri DSM 14869]
ATGTTATTCAAATATAAATCCGTATACGTGCCACAAGTGGATGAGATGGATTGTGGGGTTGCTTGTTTAGCAATGATCTT
AAAGCAATATCATTCTCGCGTATCTTTAGCACATTTACGTCATGAAGCTCGTACTAATCTTGAAGGCACAACTGCTTTAG
GACTAGTAAAGACAGCACAAAAATTTAATTTCAAAACAGAAGCCGTAAAAGCAGATATGTCTTTATTTGATGAGAATAGT
ATTCAATATCCTTTTATTGTCCACGTCCTAAAACAAGGAGAACTACTTCATTATTATGTAGTTCTTAAAAATGCTAAGAA
TTATTTAGTAATTGCAGATCCTGATCCGTCAGTTGGTGTAATAAAGATGCCTAAAGATAGGTTTGCTCAAGAATGGACAG
GGATTGCACTCTTTATGGTTCCTAATGAAGACTTTGAACCAATCAAAGAAAAGAAGAATAATTTATGGTCTCTCTTTCCA
TATATGTTTAAACAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACCATAATTAGTATTTGCAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTACATTCCAGATGGAACCTATCAGACTCTTTCGATCTTAGCTGTTGGACTAT
TAATTGCTTATGTCTTCAATTCTATCTTCTCCTATGGACAGAACTTTTTACTAAATATTTTAGGTCAAAGATTAAGTATT
GATCTAAATCTGCAATACATCAGGCATATTTTTGAATTACCAATGGAATTTTTTGTAACGAGAAGAACGGGTGAAATTAC
TTCACGTTTTTCTGATGCAAGTAGAATTATTGACGCTTTGGCAAGTACAGTTATTTCGCTCTTCTTAGACCTCTCAATTG
TGATTGTGATGGGATTAGTTTTAGCAGCGCAAAATATGACATTATTTGGGATTACATTATTAGCTTTACCAGTATATGCA
GTTGTAATTTTAGGCTTTACTAAAAAGTTCGAAAAACTAAATAATGAACAAATGGAGAGTAATGCGGTTCTTAGTTCTTC
TGTAATTGAAGATATTCAAGGAATTGAAACTATTAAGGCTTTAAATAGTGAAGATACCAGATATAGAAGAATTGATAGTC
AATTTGTAGATTACTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTGCAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTGTTCTTTGGGTTGGTGCAAAAGTTGTAATGCAAGGACAATTGAGCATTGGTCAGTTAATGAC
TTTTAATGCGTTGCTGGCATATTTCATTGATCCACTGCAAAGTATTATTAATTTACAACCGCGTCTGCAATCAGCCAGTG
TTGCGCAGAACAGATTAAATGAAGTTTATCAAGTAAAAAGTGAATTTGATAAGAAAACTATGGTTAATAATCCAGCGTTA
TTAGAAGGAACAATCTCATATGATAAAGTTGATTATCGATATGGCTATGGCGCAGATGTTTTAAAAGATATTAATCTCAA
AATTAGTCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGTTCTGGAAAATCTACGATGGTTAAGTTGTTAGTAGATT
TCTTTTCGCCAAGTAAAGGTCAGGTTACATTAAATGGACATGCAACAAGTGAAATTAATAAGCATACGTTGCGGTCATAT
GTGAATTATGTACCTCAAACTCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTGTTGTTAGGATCTAGACCAGATAT
CACTGAAGAAGATGTAATAAAGGCTTGTCAGATTGCTGGGATTGACCAAGAGATAACTAATCTACCACTGCAATTTGAAA
CAAAATTAGATGAAAAAGCAAAAATTCTATCTGGTGGACAAAAACAAAGGTTAACAATTGCTCGGGCATTATTGTCTCCT
GCAAAGGTATTTATTTTTGATGAAGTAACAAGTGGCTTAGATACAATTACCGAGAAGAAGGTAGTTGATAATTTGATGAA
GCTAAAGGACAAGACAATTATTTTTATCGCCCATCGTCTAGCAATTGCAGAACGTGCAGACAAGGTAATTGTAATTGATC
ATGGTCAAATAGTTGAAGAAGGCAGCCACAGCGAATTGATGAGTAAGCCTGGCTTTTATTATGACTTAGTGAAGGGATAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(501-651)

Peptidase C39 family (Peptidase_C39)

(7-143)

ABC transporter transmembrane region (ABC_membrane)

(169-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

56.742

99.026

0.562
  comA Streptococcus mitis SK321

56.461

99.026

0.559
  comA Streptococcus pneumoniae Rx1

56.32

99.026

0.558
  comA Streptococcus pneumoniae D39

56.32

99.026

0.558
  comA Streptococcus pneumoniae R6

56.32

99.026

0.558
  comA Streptococcus pneumoniae TIGR4

56.18

99.026

0.556
  comA Streptococcus gordonii str. Challis substr. CH1

55.056

99.026

0.545
  comA/nlmT Streptococcus mutans UA159

53.748

98.331

0.529

Multiple sequence alignment