Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQM65_RS03790 Genome accession   NZ_LS483392
Coordinates   732048..733268 (-) Length   406 a.a.
NCBI ID   WP_111691283.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC11931     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 727048..738268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM65_RS03755 (NCTC11931_00749) - 728235..728441 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQM65_RS03760 (NCTC11931_00750) - 728515..728721 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQM65_RS03765 (NCTC11931_00751) - 728796..729002 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQM65_RS03770 (NCTC11931_00752) cueR 729079..729465 (+) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  DQM65_RS03775 (NCTC11931_00753) metJ 729479..729796 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DQM65_RS03780 (NCTC11931_00754) rho 730043..731305 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  DQM65_RS03785 (NCTC11931_00755) pilD 731359..732051 (-) 693 WP_111691282.1 A24 family peptidase Machinery gene
  DQM65_RS03790 (NCTC11931_00756) pilC 732048..733268 (-) 1221 WP_111691283.1 type II secretion system F family protein Machinery gene
  DQM65_RS03795 (NCTC11931_00757) pilB 733265..734659 (-) 1395 WP_111691284.1 GspE/PulE family protein Machinery gene
  DQM65_RS03800 (NCTC11931_00758) pilA 734656..735105 (-) 450 WP_111691285.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQM65_RS03805 (NCTC11931_00759) ampD 735220..735774 (+) 555 WP_111691286.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQM65_RS03810 (NCTC11931_00760) corC 736405..737304 (+) 900 WP_111691287.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46364.64 Da        Isoelectric Point: 9.9342

>NTDB_id=1140039 DQM65_RS03790 WP_111691283.1 732048..733268(-) (pilC) [Haemophilus influenzae strain NCTC11931]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFWAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPLMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYNFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1140039 DQM65_RS03790 WP_111691283.1 732048..733268(-) (pilC) [Haemophilus influenzae strain NCTC11931]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAAAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTTGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTTACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTGCAACGTAAATTACAGAAA
ATCATGTTGTACCCCTTAATGGTGTTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTATAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATAACTTCTATCTAAAACGCCAAACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGATCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTGGCTTTGATGCTGGAGCACATCGCAGACAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.98
  pilC Haemophilus influenzae Rd KW20

97.783

100

0.978
  pilC Glaesserella parasuis strain SC1401

38.653

98.768

0.382

Multiple sequence alignment