Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   DQM45_RS07960 Genome accession   NZ_LS483388
Coordinates   1593918..1595846 (-) Length   642 a.a.
NCBI ID   WP_003085655.1    Uniprot ID   A0A4V0HD21
Organism   Streptococcus porcinus strain NCTC10999     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1588918..1600846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM45_RS07935 (NCTC10999_01615) - 1589687..1590040 (-) 354 WP_003083428.1 S1 RNA-binding domain-containing protein -
  DQM45_RS07940 (NCTC10999_01616) - 1590040..1591440 (-) 1401 WP_003086028.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM45_RS07945 (NCTC10999_01617) - 1591474..1592115 (-) 642 WP_003084661.1 response regulator transcription factor -
  DQM45_RS07950 (NCTC10999_01618) - 1592108..1593112 (-) 1005 WP_003085144.1 sensor histidine kinase -
  DQM45_RS07955 (NCTC10999_01619) liaF 1593109..1593804 (-) 696 WP_003082835.1 cell wall-active antibiotics response protein LiaF -
  DQM45_RS07960 (NCTC10999_01620) stkP/pknB 1593918..1595846 (-) 1929 WP_003085655.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQM45_RS07965 (NCTC10999_01621) - 1595843..1596583 (-) 741 WP_003083611.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQM45_RS07970 (NCTC10999_01622) rsmB 1596622..1597944 (-) 1323 WP_003082585.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQM45_RS07975 (NCTC10999_01623) fmt 1597937..1598869 (-) 933 WP_003085053.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 642 a.a.        Molecular weight: 70014.51 Da        Isoelectric Point: 9.2826

>NTDB_id=1139811 DQM45_RS07960 WP_003085655.1 1593918..1595846(-) (stkP/pknB) [Streptococcus porcinus strain NCTC10999]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKFIQDNAPLTNNQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLYEMLTGHIPYDGDSAVTIALQHFQKPLPSIVDENPSVP
QALENVVIKATAKKLSDRYATTFEMSRDLMTALSYNRSREKKLIFDDGENTKPLPKVTPTLNTSPKSSPKVTTTPTKAAQ
TSEQLKKPKKEKKRGRFLGTLFKILFALFVVGVAIFTFLILTKPTNVKVPNLSGRDLQTAKADLQALGFKVGNVEQVPSD
EVAQGNVIETNPIAGTTKREGSKVDIIVSKGSSGFKVKDYVGDDYQKAMEDLMTTYGLKRKQIKIKRVIKDDYSKQDIVL
NQSPNKGYFNPNGKTKFTLSVATTEIIGMPQLIGMTYKNAKLLLEEKGIDLNRVKVYQMNPDGTMTPVNPSSDTLIAYQN
PLLGGQISLTDTGEISLYINSDSQHTPQSSSSSSSSTEASSESSTSSGSSTTNSSSESSSGSSSTSTSTSTSTSTTSSDP
SQ

Nucleotide


Download         Length: 1929 bp        

>NTDB_id=1139811 DQM45_RS07960 WP_003085655.1 1593918..1595846(-) (stkP/pknB) [Streptococcus porcinus strain NCTC10999]
ATGATACAGATTGGCAAATTATTTGCTGGTCGATATCGCATATTAAAATCTATTGGCCGTGGAGGCATGGCAGATGTTTA
TTTAGCTAATGACTTGATCTTAGATAATGAAGATGTGGCAATAAAGGTATTGCGGACGAATTATCAGACAGATCAAGTTG
CTGTTGCACGTTTCCAAAGGGAAGCAAGAGCAATGGCTGAGCTGAATCATCCTAATATCGTAGCTATTAGAGATATAGGC
GAAGAAGACGGGCAGCAATTTTTAGTAATGGAATATGTTGATGGCGCAGATCTTAAGAAGTTCATTCAAGATAACGCACC
TCTGACTAATAATCAAGTGGTTCGGATTATGGAAGAAGTCTTATCGGCAATGACTTTAGCCCATCAAAAAGGTATTGTTC
ATAGAGATTTAAAACCACAGAACATTCTTTTAACTAAAGAAGGAGTTGTCAAAGTCACAGACTTTGGTATCGCTGTTGCT
TTTGCGGAAACCAGCTTAACACAGACTAATTCCATGTTAGGGAGTGTTCATTATTTATCGCCTGAGCAGGCACGTGGTTC
AAAAGCAACTATTCAAAGTGACATCTATGCAATGGGAATTATGCTCTATGAAATGTTGACTGGTCATATTCCCTATGATG
GGGATAGTGCGGTAACGATTGCTTTGCAACATTTCCAAAAACCGCTTCCTTCAATTGTAGATGAGAATCCTAGTGTCCCC
CAAGCTTTAGAAAACGTTGTTATTAAAGCAACAGCTAAAAAGTTAAGTGACCGTTATGCAACGACTTTTGAAATGAGCAG
AGATTTAATGACAGCCTTGAGCTATAATCGTAGTCGTGAAAAGAAGTTGATTTTTGATGACGGTGAGAACACAAAACCTT
TGCCAAAAGTGACTCCTACGCTTAATACCAGTCCTAAATCAAGTCCTAAGGTAACAACCACTCCCACTAAAGCAGCACAG
ACTTCAGAACAGCTTAAAAAGCCTAAAAAAGAGAAAAAGAGAGGACGTTTCTTAGGAACTCTTTTCAAAATTTTATTTGC
TTTATTTGTGGTTGGTGTAGCCATCTTTACGTTCTTAATTTTAACAAAACCTACTAATGTTAAAGTTCCTAACTTAAGTG
GTAGAGATTTACAGACTGCAAAAGCAGATTTACAAGCGCTAGGTTTTAAAGTTGGGAATGTTGAACAAGTACCAAGTGAT
GAAGTTGCACAAGGAAATGTCATTGAAACTAATCCGATCGCAGGAACAACAAAACGTGAGGGTTCTAAGGTAGACATTAT
AGTCTCTAAAGGAAGTAGTGGCTTTAAAGTTAAGGATTATGTAGGTGACGATTATCAAAAGGCTATGGAAGACTTAATGA
CTACTTACGGTTTAAAACGTAAACAAATAAAGATTAAACGTGTTATAAAAGATGATTATAGCAAGCAAGATATTGTTTTA
AACCAATCACCAAATAAGGGCTACTTTAATCCCAACGGAAAAACGAAGTTTACCTTATCGGTTGCAACCACAGAAATAAT
TGGGATGCCACAACTCATTGGAATGACCTATAAGAATGCTAAACTCTTACTTGAAGAGAAGGGAATTGATTTAAATCGTG
TTAAGGTTTATCAGATGAATCCTGATGGTACTATGACACCGGTTAATCCAAGCTCTGATACACTAATTGCTTATCAAAAT
CCTCTACTTGGCGGGCAGATTTCGCTGACTGACACAGGAGAAATCAGTCTTTATATTAATAGTGATAGCCAACATACTCC
ACAATCAAGTAGTTCAAGTTCATCAAGTACAGAAGCTAGTTCTGAGTCTAGTACTAGTTCAGGTTCTTCCACCACCAATT
CATCCTCTGAGTCGAGCTCTGGATCCAGCTCAACCAGCACCTCAACCAGTACTAGCACATCTACAACCAGTTCGGATCCA
AGTCAATAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(367-430)

PASTA domain (PASTA)

(509-580)

Protein kinase domain (Pkinase)

(12-233)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0HD21

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

59.23

97.04

0.575
  pknB Streptococcus mutans UA159

63.122

90.81

0.573
  stkP Streptococcus pneumoniae TIGR4

60.652

71.651

0.435
  stkP Streptococcus pneumoniae D39

60.217

71.651

0.431
  stkP Streptococcus pneumoniae R6

60.217

71.651

0.431
  stkP Streptococcus pneumoniae Rx1

60

71.651

0.43

Multiple sequence alignment