Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQM45_RS02050 Genome accession   NZ_LS483388
Coordinates   380064..380819 (+) Length   251 a.a.
NCBI ID   WP_003085872.1    Uniprot ID   -
Organism   Streptococcus porcinus strain NCTC10999     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 375064..385819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM45_RS02035 (NCTC10999_00414) - 375319..376890 (-) 1572 WP_003083433.1 ABC transporter substrate-binding protein/permease -
  DQM45_RS02040 (NCTC10999_00415) - 377080..378984 (+) 1905 WP_003084460.1 DUF2207 domain-containing protein -
  DQM45_RS02045 (NCTC10999_00416) - 379109..379948 (+) 840 WP_003083097.1 undecaprenyl-diphosphate phosphatase -
  DQM45_RS02050 (NCTC10999_00417) mecA 380064..380819 (+) 756 WP_003085872.1 adaptor protein MecA Regulator
  DQM45_RS02055 (NCTC10999_00418) - 380826..381980 (+) 1155 WP_003084251.1 glycosyltransferase family 4 protein -
  DQM45_RS02060 (NCTC10999_00419) sufC 382106..382876 (+) 771 WP_003083205.1 Fe-S cluster assembly ATPase SufC -
  DQM45_RS02065 (NCTC10999_00420) sufD 382970..384235 (+) 1266 WP_003084770.1 Fe-S cluster assembly protein SufD -
  DQM45_RS02070 (NCTC10999_00421) - 384250..385476 (+) 1227 WP_003083731.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29186.14 Da        Isoelectric Point: 4.1347

>NTDB_id=1139783 DQM45_RS02050 WP_003085872.1 380064..380819(+) (mecA) [Streptococcus porcinus strain NCTC10999]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRKDRLDVFVTKSEL
SKEIDFEDLTDLGDVSQMTPEDFFKTIEKNMIEKGDVNAHEKLEKIEEMLEEAVEASQSQTTAADEPAQIVEPMDYVHYV
FDFLTIEEVISFSKIVNFPIEASELYKETSRYHLTILLDIQNQPAYFANIMYARLIEHALPGSKTRAYLQEHATLLIEDQ
AIEQLKKIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1139783 DQM45_RS02050 WP_003085872.1 380064..380819(+) (mecA) [Streptococcus porcinus strain NCTC10999]
ATGGAAATGAAACAAATTAGTGAAACAACACTAAAAATAACGATTAGCATGGATGATTTAGAAGAAAGAGGAATGGAATT
GAAAGATTTCTTGATTCCTCAGGAAAAAACAGAAGAATTCTTCTATACCGTTATGGATGAGTTGGATTTACCTGAAAACT
TTAAAGATAGTGGGATGTTGAGTTTCAGAGTTACCCCACGTAAAGATCGTTTAGATGTTTTTGTTACTAAGTCAGAATTA
TCTAAAGAAATTGATTTTGAAGATTTAACTGATTTAGGAGATGTTTCTCAGATGACACCCGAAGATTTTTTTAAAACAAT
TGAAAAAAACATGATAGAAAAAGGCGATGTCAATGCCCATGAAAAATTGGAAAAAATTGAAGAAATGTTAGAAGAAGCAG
TTGAGGCAAGCCAATCTCAAACTACAGCAGCTGATGAACCTGCTCAGATTGTTGAACCAATGGACTATGTTCATTATGTT
TTTGATTTCCTAACGATAGAGGAAGTCATTAGCTTTTCTAAGATAGTCAACTTTCCAATTGAAGCTTCAGAGCTTTACAA
GGAAACTAGTCGCTATCACCTGACAATCTTACTTGATATTCAAAATCAGCCAGCCTACTTTGCTAATATTATGTATGCTA
GGTTAATTGAACATGCACTACCTGGTTCAAAAACACGTGCTTATTTGCAAGAACATGCAACCTTACTCATTGAAGATCAA
GCAATAGAGCAGTTGAAAAAGATTGAATTGGTGTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

61.694

98.805

0.61
  mecA Streptococcus thermophilus LMD-9

57.085

98.406

0.562
  mecA Streptococcus thermophilus LMG 18311

56.68

98.406

0.558
  mecA Streptococcus pneumoniae TIGR4

45.418

100

0.454
  mecA Streptococcus pneumoniae Rx1

45.02

100

0.45
  mecA Streptococcus pneumoniae D39

45.02

100

0.45
  mecA Streptococcus pneumoniae R6

45.02

100

0.45

Multiple sequence alignment