Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DQM63_RS08865 Genome accession   NZ_LS483385
Coordinates   1771746..1773599 (-) Length   617 a.a.
NCBI ID   WP_002903266.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1766746..1778599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS08840 (NCTC7863_01742) - 1767477..1767839 (-) 363 WP_002901252.1 S1 RNA-binding domain-containing protein -
  DQM63_RS08845 (NCTC7863_01743) - 1767839..1769239 (-) 1401 WP_002903263.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM63_RS08850 (NCTC7863_01744) - 1769279..1769911 (-) 633 WP_002903264.1 response regulator transcription factor -
  DQM63_RS08855 (NCTC7863_01745) - 1769889..1770908 (-) 1020 WP_002914269.1 sensor histidine kinase -
  DQM63_RS08860 (NCTC7863_01746) liaF 1770905..1771600 (-) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  DQM63_RS08865 (NCTC7863_01747) stkP 1771746..1773599 (-) 1854 WP_002903266.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DQM63_RS08870 (NCTC7863_01748) - 1773596..1774336 (-) 741 WP_002903268.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DQM63_RS08875 (NCTC7863_01749) rsmB 1774355..1775671 (-) 1317 WP_002903269.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DQM63_RS08880 (NCTC7863_01750) fmt 1775661..1776596 (-) 936 WP_002903270.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67326.16 Da        Isoelectric Point: 6.4426

>NTDB_id=1139645 DQM63_RS08865 WP_002903266.1 1771746..1773599(-) (stkP) [Streptococcus sanguinis strain NCTC7863]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENSPISNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYERRNEKKLVFDDVAKADTKTLPKISPVPQPAVPPVKSTPPKAEAT
EVKEETPDAVKKVPKKRRLRTRYKVLFFAVLLVLAAFVVLLYNSPSNTSVPDVSGQTVAEARSAIEAKKLVVGDEKEEYS
DNVESGKVIKTDPQANSQRREGSKIDLIISKGPKTFVMEDYVGQAKSAAVENLKTNYNVSEKLIEIVEEESDEYEPGQVI
RQSPAAGSTYDLTSNHKIKLTVAKEVTSVSMPDFGSMQYTYANARSYLIQMGISSSRIERVVDRSVTSTQADLVTSQSPA
AGQTIDLKSNEKITLYVTEATTPSSSSSSSSSSSSSSKSSSSSEDSGHGTSSSSSDG

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=1139645 DQM63_RS08865 WP_002903266.1 1771746..1773599(-) (stkP) [Streptococcus sanguinis strain NCTC7863]
ATGATTCAAATCGGCAAAATCTTTGCCGGGCGATATAAAATCATCAAGCAGATTGGCCGCGGAGGCATGGCAGATGTCTA
TTTGGCCAAGGACTTGATTTTGGATGGTGAGGAAGTTGCGGTAAAGGTTCTTAGGACCAATTACCAGACAGATCCTATCG
CTGTCGCGCGTTTCCAGCGGGAAGCCAAGGCGATGGCTGACTTGGACCATCCGCACATCGTTCGGATTACTGATATTGGG
GAAGAAGATGGCCAGCAGTATCTGGCTATGGAATACGTGGCAGGTCTTGACCTCAAGCGCTATATCAAAGAGAATTCTCC
GATTTCAAATGAAGAAGCAGTCAGAATCATGGGACAAATCTTGCTGGCAATGCGCTTGGCGCATACACGAGGTATTGTCC
ATCGTGACCTGAAACCACAAAATGTCCTCTTGACCCCAGATGGCAATGCCAAGGTAACAGACTTTGGGATTGCGGTGGCC
TTTGCAGAGACAAGTCTGACTCAGACTAACTCAATGCTAGGCTCGGTTCATTATCTATCACCTGAGCAGGCGCGTGGCTC
TAAAGCAACTGTTCAGAGTGATATTTATGCGATGGGGATTATTTTTTATGAAATGCTGACTGGTCATATCCCTTATGATG
GGGATAGTGCCGTTACGATTGCCCTGCAGCATTTCCAAAAGCCGCTGCCATCCATCATTTCTGAAAATCCTAATGTGCCT
CAAGCCCTGGAAAATGTGGTCATTAAGGCGACAGCCAAAAAACTGACGGATCGTTATCAGTCAGTTGCAGAGATGTATGT
TGACTTGTCCAGCAGCTTATCTTATGAGCGTCGTAATGAAAAGAAATTAGTCTTTGATGATGTAGCGAAAGCAGACACCA
AGACCTTACCAAAAATCTCACCTGTACCGCAGCCAGCAGTTCCACCTGTTAAGTCAACACCGCCTAAAGCGGAAGCGACT
GAAGTTAAGGAAGAGACACCAGATGCGGTTAAGAAAGTTCCAAAGAAACGTCGTTTGAGAACGCGTTACAAGGTGCTTTT
CTTTGCAGTCTTATTGGTTTTGGCAGCTTTTGTTGTCCTTCTCTATAACAGCCCGTCCAATACCAGCGTGCCAGATGTTT
CTGGTCAGACTGTAGCAGAGGCTCGCTCCGCTATCGAAGCTAAGAAGCTGGTTGTCGGAGACGAAAAGGAAGAATACAGC
GACAATGTCGAATCTGGCAAAGTCATTAAAACTGATCCACAGGCCAATAGTCAGCGCCGTGAAGGCAGTAAGATCGACCT
GATTATCTCCAAGGGACCCAAGACCTTTGTAATGGAAGATTATGTCGGACAAGCAAAATCAGCCGCAGTTGAAAATTTGA
AAACAAACTATAATGTTTCTGAGAAATTGATTGAGATTGTTGAGGAGGAATCGGACGAGTACGAGCCAGGTCAGGTCATT
CGTCAGTCACCGGCAGCTGGTTCGACCTATGATTTGACTTCTAATCATAAGATCAAGTTGACAGTGGCCAAAGAAGTAAC
TAGTGTATCCATGCCTGACTTTGGCAGCATGCAGTACACCTACGCTAATGCTCGTTCTTACTTGATCCAAATGGGAATTT
CTTCTTCTCGAATTGAGCGAGTTGTTGACCGTTCGGTCACTTCGACTCAGGCAGACTTGGTAACTTCCCAGTCACCAGCG
GCAGGTCAGACAATTGACCTCAAATCTAATGAAAAAATCACTCTTTATGTGACAGAAGCAACGACACCATCGTCATCTAG
CTCGTCATCTTCATCGTCTAGTAGCAGCTCAAAGAGCAGCTCATCGTCTGAAGATAGCGGACATGGAACTAGTTCCAGCT
CATCTGATGGTTGA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(370-431)

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(437-504)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.201

98.217

0.621
  stkP Streptococcus pneumoniae D39

62.871

98.217

0.618
  stkP Streptococcus pneumoniae R6

62.871

98.217

0.618
  stkP Streptococcus pneumoniae Rx1

62.706

98.217

0.616
  pknB Streptococcus mutans UA159

58.603

95.138

0.558
  stkP/pknB Streptococcus salivarius strain HSISS4

55.927

97.083

0.543

Multiple sequence alignment