Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   DQM63_RS05745 Genome accession   NZ_LS483385
Coordinates   1181819..1182661 (-) Length   280 a.a.
NCBI ID   WP_002900343.1    Uniprot ID   F0IUZ6
Organism   Streptococcus sanguinis strain NCTC7863     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1176819..1187661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS05730 (NCTC7863_01124) trmFO 1177660..1178994 (-) 1335 WP_002913557.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  DQM63_RS05735 (NCTC7863_01125) - 1179088..1179582 (-) 495 WP_002913556.1 hypothetical protein -
  DQM63_RS05740 (NCTC7863_01126) topA 1179641..1181734 (-) 2094 WP_002913555.1 type I DNA topoisomerase -
  DQM63_RS05745 (NCTC7863_01127) dprA/cilB/dalA 1181819..1182661 (-) 843 WP_002900343.1 DNA-processing protein DprA Machinery gene
  DQM63_RS05750 (NCTC7863_01128) - 1182792..1183355 (-) 564 WP_002913554.1 sugar O-acetyltransferase -
  DQM63_RS05755 - 1183331..1184174 (-) 844 Protein_1083 PRD domain-containing protein -
  DQM63_RS05760 (NCTC7863_01131) - 1184192..1184956 (-) 765 WP_002913551.1 ribonuclease HII -
  DQM63_RS05765 (NCTC7863_01132) ylqF 1184943..1185794 (-) 852 WP_002913550.1 ribosome biogenesis GTPase YlqF -
  DQM63_RS05770 (NCTC7863_01133) - 1185936..1186274 (-) 339 WP_002895476.1 ATP cone domain-containing protein -
  DQM63_RS05775 (NCTC7863_01134) - 1186520..1187119 (-) 600 WP_002900332.1 hypothetical protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30978.66 Da        Isoelectric Point: 6.7409

>NTDB_id=1139634 DQM63_RS05745 WP_002900343.1 1181819..1182661(-) (dprA/cilB/dalA) [Streptococcus sanguinis strain NCTC7863]
MNNFEIYKMKKAGLTNHQVLNVLRYAESRDGKLSLRDKAVVSECRNPALFIEKYKRLDLPALKEEFELFPSFSILDDIYP
WDLCEIYDAPTLLFYQGNLNLLELPKAAVVGSRDSSKQGNASVQKIIKELNNELVIVSGLARGIDTAAHMAALQNGGQTI
AVIGTGLDVFYPKANKKLQAYIGKNHLLLTEYGPGEQPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGKSDGCHHLIQEGAKCITSGSDVLSEFDF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1139634 DQM63_RS05745 WP_002900343.1 1181819..1182661(-) (dprA/cilB/dalA) [Streptococcus sanguinis strain NCTC7863]
ATGAATAATTTTGAGATTTATAAAATGAAAAAAGCTGGTTTGACTAATCATCAGGTTTTAAATGTTTTGAGATATGCTGA
GAGTAGAGATGGCAAGCTTTCTCTGCGAGATAAGGCTGTCGTATCTGAGTGCCGCAATCCTGCACTCTTTATAGAGAAAT
ACAAGAGGCTTGATTTACCAGCTTTGAAGGAAGAATTTGAACTTTTTCCGTCCTTTTCTATCTTGGATGATATTTATCCT
TGGGATTTATGTGAAATTTACGATGCCCCGACTTTGTTATTTTATCAGGGAAATCTAAATCTACTAGAATTGCCCAAAGC
TGCGGTCGTTGGCAGTAGAGACAGCAGCAAGCAAGGAAATGCCTCAGTACAAAAGATTATCAAAGAGCTAAATAATGAAT
TGGTTATCGTCAGCGGGCTGGCTCGAGGGATTGATACAGCAGCTCACATGGCTGCTCTACAAAACGGAGGTCAGACCATT
GCTGTCATTGGGACGGGATTAGATGTCTTCTATCCCAAGGCTAACAAAAAATTACAAGCTTACATTGGCAAAAATCATTT
ATTGCTGACAGAGTATGGTCCAGGTGAACAGCCTTTGAAATTTCATTTTCCAGAGCGAAATCGTATCATCGCTGGTCTCT
GTCGAGGCGTCATCGTGGCAGAAGCTAAGATGCGTTCAGGCAGTCTGATTACCTGTGAGCGAGCCATGGAAGAAGGGCGG
GATGTCTTTGCTATTCCGGGGTCAATTTTAGATGGAAAATCTGACGGTTGCCATCATTTGATTCAAGAGGGTGCAAAGTG
CATCACATCAGGCTCTGACGTCCTTTCTGAGTTTGATTTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(74-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F0IUZ6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

77.143

100

0.771
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.786

100

0.768
  dprA/cilB/dalA Streptococcus mitis SK321

76.429

100

0.764
  dprA Streptococcus mutans UA159

67.143

100

0.671
  dprA Lactococcus lactis subsp. cremoris KW2

57.194

99.286

0.568

Multiple sequence alignment