Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQM63_RS02060 Genome accession   NZ_LS483385
Coordinates   390023..390775 (+) Length   250 a.a.
NCBI ID   WP_002913962.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 385023..395775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS02045 (NCTC7863_00399) - 385273..386838 (-) 1566 WP_002902426.1 ABC transporter substrate-binding protein/permease -
  DQM63_RS02050 (NCTC7863_00400) - 386970..388865 (+) 1896 WP_002902427.1 DUF2207 domain-containing protein -
  DQM63_RS02055 (NCTC7863_00401) - 389005..389847 (+) 843 WP_002913963.1 undecaprenyl-diphosphate phosphatase -
  DQM63_RS02060 (NCTC7863_00402) mecA 390023..390775 (+) 753 WP_002913962.1 adaptor protein MecA Regulator
  DQM63_RS02065 (NCTC7863_00403) - 390766..391932 (+) 1167 WP_002913961.1 glycosyltransferase family 4 protein -
  DQM63_RS02070 (NCTC7863_00404) sufC 392022..392792 (+) 771 WP_002893635.1 Fe-S cluster assembly ATPase SufC -
  DQM63_RS02075 (NCTC7863_00405) sufD 392834..394096 (+) 1263 WP_002902438.1 Fe-S cluster assembly protein SufD -
  DQM63_RS02080 (NCTC7863_00406) - 394137..395369 (+) 1233 WP_002902440.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28710.32 Da        Isoelectric Point: 3.9783

>NTDB_id=1139609 DQM63_RS02060 WP_002913962.1 390023..390775(+) (mecA) [Streptococcus sanguinis strain NCTC7863]
MEMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKL
DKNLSFEDLADLPDMDELSHMSPDEFLKTLEKSIFEKSKEDIEAVQSLETAEAEEGEQLSQEAAAEQSAENAERYIYYIL
RFEDIKAAAAFAQTVDYKIDLSELYKYDSAYYLTILVDVEGFPERYPAWLLAKMREFADDSDITRAVLQEHGHLLLVTDA
VSGLQKVECL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=1139609 DQM63_RS02060 WP_002913962.1 390023..390775(+) (mecA) [Streptococcus sanguinis strain NCTC7863]
ATGGAAATGAAACAGATTAGTGATTCGACCATAAAAATCACGATTCAGCTGGAAGATTTGGAAGAGCGCGGTATGGAAAT
GGCCGATTTCTTGGTTCCCCAAGAAAAGACGGAAGAGTTTTTCTATACCATCTTAGATGAGTTGGAAATGCCGGATAATT
TTTTGGACAGCGGTATGCTGAGCTTCCGTGTGACGCCTAAGCCAGATAAGGTGGATGTGTTTGTTACCAAGTCTAAGTTG
GATAAGAATCTGAGTTTTGAGGATTTGGCAGATCTGCCAGACATGGATGAGCTGTCTCATATGTCTCCAGATGAATTCCT
CAAGACACTGGAAAAGAGCATTTTTGAAAAGAGTAAGGAAGACATAGAAGCAGTCCAATCTTTGGAAACGGCAGAAGCTG
AGGAAGGGGAACAGCTTTCTCAGGAGGCGGCTGCTGAGCAGTCGGCAGAAAATGCTGAGCGTTACATTTACTATATCCTG
CGTTTTGAAGATATTAAGGCTGCTGCGGCTTTTGCCCAGACGGTGGATTATAAGATTGACTTATCAGAACTTTATAAGTA
TGATTCAGCTTATTATTTGACGATTTTAGTAGATGTTGAGGGCTTCCCAGAGCGCTATCCAGCTTGGCTTTTGGCTAAGA
TGCGTGAATTCGCAGATGATTCAGATATCACTCGGGCAGTGCTGCAGGAGCACGGACATCTTCTTTTGGTGACAGATGCC
GTCTCCGGCCTGCAGAAGGTTGAATGCCTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.826

98.8

0.68
  mecA Streptococcus pneumoniae D39

68.826

98.8

0.68
  mecA Streptococcus pneumoniae R6

68.826

98.8

0.68
  mecA Streptococcus pneumoniae TIGR4

68.421

98.8

0.676
  mecA Streptococcus mutans UA159

49.798

98.8

0.492
  mecA Streptococcus thermophilus LMD-9

48.996

99.6

0.488
  mecA Streptococcus thermophilus LMG 18311

48.594

99.6

0.484

Multiple sequence alignment