Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DQM67_RS08185 Genome accession   NZ_LS483383
Coordinates   1621744..1622487 (-) Length   247 a.a.
NCBI ID   WP_005591765.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1616744..1627487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS08165 (NCTC12479_01588) - 1617149..1618381 (-) 1233 WP_005591769.1 cysteine desulfurase -
  DQM67_RS08170 (NCTC12479_01589) sufD 1618423..1619685 (-) 1263 WP_005591768.1 Fe-S cluster assembly protein SufD -
  DQM67_RS08175 (NCTC12479_01590) sufC 1619727..1620497 (-) 771 WP_005591767.1 Fe-S cluster assembly ATPase SufC -
  DQM67_RS08180 (NCTC12479_01591) - 1620581..1621753 (-) 1173 WP_005591766.1 glycosyltransferase family 4 protein -
  DQM67_RS08185 (NCTC12479_01592) mecA 1621744..1622487 (-) 744 WP_005591765.1 adaptor protein MecA Regulator
  DQM67_RS08190 (NCTC12479_01593) - 1622599..1623441 (-) 843 WP_005591764.1 undecaprenyl-diphosphate phosphatase -
  DQM67_RS08195 (NCTC12479_01594) - 1623530..1625389 (-) 1860 WP_231913450.1 DUF2207 domain-containing protein -
  DQM67_RS08200 (NCTC12479_01595) - 1625556..1627121 (+) 1566 WP_005592314.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28560.10 Da        Isoelectric Point: 3.9226

>NTDB_id=1139527 DQM67_RS08185 WP_005591765.1 1621744..1622487(-) (mecA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MEVKQINDSTIKITIQLEDLEEHGMEIADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTRSKI
DKNLNFEDLGNLPDMDELSQMSPDEFLKTLEKNIFEKSKDDLEAVKSLEAAEADQEASVDSSEDREENLDRYVYYILSFT
DLQSAVSFAKTVDYPIDLSELYKYDSAYYLTILVDLEDQPALYPAWLLAKMREFAEDTDITRSVLQEHGRLLLVTEAIQQ
LQKVECV

Nucleotide


Download         Length: 744 bp        

>NTDB_id=1139527 DQM67_RS08185 WP_005591765.1 1621744..1622487(-) (mecA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGGAAGTGAAACAGATTAATGATTCGACGATTAAAATCACCATCCAGTTGGAAGATTTGGAAGAACACGGAATGGAAAT
TGCAGATTTCCTAGTGCCCCAAGAAAAAACAGAAGAATTTTTCTATACTATTTTGGATGAGTTGGAAATGCCGGAAAGCT
TTTTAGACAGTGGCATGCTCAGCTTTCGAGTGACGCCTAAGCCAGACAAGTTGGATGTCTTTGTGACGAGATCCAAGATT
GATAAGAATTTGAATTTTGAAGATTTGGGAAATCTACCGGATATGGATGAGCTCAGCCAGATGTCGCCAGATGAATTCTT
AAAGACTTTGGAAAAAAACATCTTTGAAAAGAGTAAGGATGACCTTGAGGCGGTCAAATCTTTAGAAGCAGCAGAGGCTG
ATCAGGAGGCCTCTGTAGATTCTTCAGAAGATAGGGAAGAAAATCTAGACCGTTATGTCTACTATATTTTGTCATTTACT
GATTTGCAGAGTGCAGTTTCTTTCGCCAAAACGGTTGACTACCCAATAGACCTATCAGAACTTTATAAATATGACTCTGC
CTACTACCTGACTATTTTGGTAGATTTGGAAGATCAACCTGCTCTTTATCCAGCTTGGTTACTGGCTAAAATGCGTGAAT
TTGCTGAGGATACAGATATTACACGTTCTGTCCTACAAGAACACGGGCGTCTGCTTTTGGTGACAGAAGCCATCCAACAG
TTGCAGAAAGTTGAATGCGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.984

98.785

0.652
  mecA Streptococcus pneumoniae D39

65.984

98.785

0.652
  mecA Streptococcus pneumoniae R6

65.984

98.785

0.652
  mecA Streptococcus pneumoniae TIGR4

65.574

98.785

0.648
  mecA Streptococcus mutans UA159

49.59

98.785

0.49
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.474
  mecA Streptococcus thermophilus LMD-9

46.586

100

0.47

Multiple sequence alignment