Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQM67_RS04990 Genome accession   NZ_LS483383
Coordinates   978780..980159 (-) Length   459 a.a.
NCBI ID   WP_005590266.1    Uniprot ID   A0A428GKG3
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 973780..985159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS04965 (NCTC12479_00961) udk 973948..974583 (-) 636 WP_005591973.1 uridine kinase -
  DQM67_RS04970 (NCTC12479_00962) - 974688..975668 (+) 981 WP_005590270.1 Gfo/Idh/MocA family protein -
  DQM67_RS04975 (NCTC12479_00963) - 975661..976749 (+) 1089 WP_282645401.1 DEAD/DEAH box helicase -
  DQM67_RS04980 (NCTC12479_00964) - 976832..978229 (-) 1398 WP_005590268.1 polysaccharide deacetylase family protein -
  DQM67_RS04985 (NCTC12479_00965) - 978319..978705 (-) 387 WP_005590267.1 VOC family protein -
  DQM67_RS04990 (NCTC12479_00966) ciaH 978780..980159 (-) 1380 WP_005590266.1 sensor histidine kinase KdpD Regulator
  DQM67_RS04995 (NCTC12479_00967) ciaR 980149..980823 (-) 675 WP_005590265.1 response regulator transcription factor Regulator
  DQM67_RS05000 (NCTC12479_00968) - 980944..981384 (-) 441 WP_005590264.1 hypothetical protein -
  DQM67_RS05005 (NCTC12479_00969) - 981603..984146 (-) 2544 WP_005591931.1 M1 family metallopeptidase -
  DQM67_RS05010 (NCTC12479_00970) phoU 984371..985024 (-) 654 WP_005591940.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 52249.66 Da        Isoelectric Point: 9.2372

>NTDB_id=1139505 DQM67_RS04990 WP_005590266.1 978780..980159(-) (ciaH) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MLNKLKKALYADDFSYFIRYFGVFTLIFSAMTLIIIQVMRSSLYTTVDDNLKSLSQNPAWVANLAYRTTGRQYQQPENKD
SENRDSESVQAHDIKIEEPGRVNVSANTSAILLNDDYQNVSAKNSFLNFDAIKFNKRFLNQIKQIQLTNSYGQVESYRAY
MFDIDPNDEIENVKYAVVMTSISQLEQTSEKHEKLIAIVMISFWGISLIASIYLARMSVKPLLDSMQKQKSFVENASHEL
RTPLAVLQNRLESLFRKPEATIMESSESIASSLEEVRNMRLLTTNLLNLARRDDGIKPEYGEVTPDFFTTAFSNYAIIAE
ESDKVFDFKNLVSKSITTDKVLLKQVMTILFDNAIKYTEEDGEIYFVASANDRSLTLRISDNGPGIAGDDKKKVFDRFYR
VDKARTRQKGGFGLGLSLAKQIVDALKGTITVKDNKPRGTIFEIKVPLRSDIRKRISKS

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=1139505 DQM67_RS04990 WP_005590266.1 978780..980159(-) (ciaH) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGCTGAATAAACTCAAAAAAGCCTTATATGCGGATGATTTTTCTTATTTCATTCGCTATTTTGGTGTGTTCACCCTGAT
TTTTTCGGCCATGACGCTCATTATTATCCAAGTCATGCGCTCTAGCCTTTACACGACCGTTGATGATAATCTCAAAAGTC
TCAGTCAAAATCCCGCCTGGGTAGCCAATCTAGCCTATCGGACGACGGGCCGGCAATACCAACAGCCAGAGAATAAGGAT
TCAGAGAACAGAGATTCAGAGTCTGTGCAAGCTCATGATATCAAGATTGAGGAACCGGGTAGGGTAAATGTTAGCGCCAA
TACTTCAGCTATTCTTTTGAATGATGATTATCAGAATGTATCAGCAAAAAATAGCTTTTTAAACTTTGATGCGATTAAAT
TTAACAAACGCTTTCTTAATCAGATCAAGCAAATACAACTAACTAATAGCTATGGACAGGTCGAGAGTTATCGGGCCTAT
ATGTTTGACATTGATCCAAATGATGAAATTGAAAATGTCAAATACGCAGTTGTCATGACTAGTATCAGCCAGCTGGAGCA
GACTAGCGAAAAGCATGAAAAGCTGATTGCCATCGTCATGATTAGTTTCTGGGGTATTTCCTTGATTGCCAGTATCTATC
TGGCGCGGATGAGTGTCAAGCCTCTCTTGGATAGCATGCAGAAGCAGAAATCCTTTGTTGAAAATGCTAGCCACGAATTG
CGGACGCCTCTAGCTGTGCTGCAAAATCGTCTGGAATCTCTTTTCCGTAAGCCCGAGGCTACGATTATGGAGTCTAGTGA
GAGTATCGCGTCCAGTTTAGAGGAAGTGCGAAATATGCGCCTGTTGACCACCAACTTACTCAACCTAGCTCGGCGCGATG
ACGGTATCAAGCCAGAATACGGTGAAGTCACACCAGACTTCTTCACGACAGCTTTTTCTAACTATGCTATTATTGCAGAG
GAAAGCGACAAGGTCTTTGATTTCAAAAATCTGGTTTCAAAATCAATCACGACAGACAAGGTCTTGCTCAAGCAGGTTAT
GACCATCCTTTTTGATAATGCTATCAAATACACGGAAGAAGATGGAGAGATCTATTTCGTGGCTTCCGCCAATGATCGGA
GCTTGACCTTGCGTATTTCTGACAATGGTCCAGGGATTGCGGGCGATGACAAGAAAAAAGTCTTCGATCGTTTTTATCGG
GTGGATAAGGCACGGACTCGTCAAAAAGGTGGATTTGGACTAGGACTATCCTTGGCGAAACAAATCGTGGACGCCTTAAA
AGGAACCATTACAGTCAAAGACAACAAACCGCGTGGAACCATCTTTGAAATCAAAGTTCCCCTTAGGTCAGATATTAGAA
AACGAATTAGCAAAAGCTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(230-295)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(339-449)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A428GKG3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

63.895

99.564

0.636
  ciaH Streptococcus pneumoniae D39

63.895

99.564

0.636
  ciaH Streptococcus pneumoniae R6

63.895

99.564

0.636
  ciaH Streptococcus pneumoniae TIGR4

63.895

99.564

0.636
  ciaH Streptococcus mutans UA159

52.242

97.168

0.508

Multiple sequence alignment