Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   DQM69_RS10400 Genome accession   NZ_LS483381
Coordinates   2142651..2143859 (+) Length   402 a.a.
NCBI ID   WP_109982804.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2137651..2148859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS10380 (NCTC10921_02073) - 2138710..2141322 (+) 2613 WP_109982803.1 YfhO family protein -
  DQM69_RS10395 (NCTC10921_02076) rlmH 2141975..2142454 (-) 480 WP_019770428.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQM69_RS10400 (NCTC10921_02077) htrA 2142651..2143859 (+) 1209 WP_109982804.1 S1C family serine protease Regulator
  DQM69_RS10405 (NCTC10921_02078) spo0J 2143919..2144686 (+) 768 WP_019770069.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 42312.03 Da        Isoelectric Point: 7.3136

>NTDB_id=1139424 DQM69_RS10400 WP_109982804.1 2142651..2143859(+) (htrA) [Streptococcus sobrinus strain NCTC10921]
MKKVKKISWKKILKPFLMLLIGFLGGLLATFVMLKMSGINTSLGKNVVSHTQYNNSSDVTKAVDKVKDAVVTVNNYQELS
DSQAKAADEAGLEKDKDGLTPVAQGSGVIYKKDGKSAYVVTNAHVVSGAKKLTLMLGGETDRSKAIKGELIGSDTYSDIA
VIKISSDKVTKVAEFADSSSVKVGETAIAIGSPLDKKFANTVTQGIISALDRTVTLTAEDGTTIQTKAFQTDAAINPGNS
GGALINIEGQVIGINSSKISLEGSEGLGFAIPSNDVVSTINQLEKNGKVSRPALGITMGDLSSASSSVKDKVDVPSDVTK
GVVVGSVQSDMPADGKLKEYDVITKIDDKDVSSVAELQEELYKHKLGDTVTLTFYRDGSKKTADIKLNKSSDDLDSSSSS
SK

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=1139424 DQM69_RS10400 WP_109982804.1 2142651..2143859(+) (htrA) [Streptococcus sobrinus strain NCTC10921]
TTGAAAAAAGTTAAAAAGATTTCTTGGAAAAAAATCCTGAAACCTTTCTTGATGCTACTGATTGGTTTTCTAGGTGGCTT
ATTGGCAACCTTCGTCATGCTAAAAATGAGTGGTATCAATACATCTCTGGGCAAAAATGTCGTCAGCCATACCCAATACA
ATAATTCATCTGACGTCACAAAGGCTGTAGATAAGGTTAAGGATGCTGTTGTCACAGTTAATAATTACCAAGAGCTGTCT
GATTCTCAAGCCAAGGCTGCTGATGAAGCTGGTTTGGAAAAGGATAAGGATGGCTTGACTCCAGTTGCTCAAGGTTCTGG
GGTTATCTATAAAAAAGATGGAAAAAGTGCCTATGTCGTTACTAATGCCCATGTTGTTAGTGGCGCTAAGAAACTAACTC
TCATGTTGGGTGGTGAAACTGATCGCAGTAAAGCCATCAAAGGGGAATTAATCGGTTCAGATACTTATTCCGATATTGCT
GTTATCAAGATTTCCTCTGATAAGGTGACTAAGGTAGCTGAGTTTGCTGACTCGTCATCTGTTAAGGTTGGTGAAACAGC
CATTGCTATCGGTAGCCCTTTAGACAAGAAATTTGCTAATACTGTTACTCAAGGTATTATTTCAGCTTTGGACCGAACAG
TAACTCTGACCGCTGAAGATGGAACAACAATCCAAACCAAAGCCTTCCAAACCGATGCGGCTATCAACCCTGGTAACTCA
GGCGGTGCCCTTATCAATATTGAAGGTCAAGTTATCGGTATCAATTCTAGTAAAATTTCTCTAGAGGGTTCTGAAGGTCT
CGGCTTTGCTATCCCTTCTAATGATGTTGTTTCTACTATTAATCAGTTAGAAAAGAATGGTAAGGTTAGCCGCCCAGCCC
TCGGCATTACCATGGGCGATTTAAGCAGCGCAAGCTCTTCCGTTAAGGACAAGGTTGATGTTCCTAGTGATGTTACCAAA
GGTGTTGTGGTTGGTTCTGTCCAATCCGATATGCCAGCTGATGGTAAGTTGAAAGAATACGATGTTATCACCAAGATAGA
TGATAAGGATGTTAGCTCTGTTGCTGAGTTACAAGAAGAACTTTACAAGCACAAACTTGGTGACACCGTCACCCTGACCT
TCTACCGCGACGGTAGCAAGAAGACAGCTGACATTAAATTGAATAAATCTAGCGATGATTTGGATTCATCCTCATCAAGC
AGTAAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(292-387)

Trypsin-like peptidase domain (Trypsin_2)

(105-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.511

100

0.572
  htrA Streptococcus gordonii str. Challis substr. CH1

54.156

98.756

0.535
  htrA Streptococcus pneumoniae D39

53.234

100

0.532
  htrA Streptococcus pneumoniae TIGR4

53.234

100

0.532
  htrA Streptococcus mitis NCTC 12261

53.234

100

0.532
  htrA Streptococcus pneumoniae R6

53.234

100

0.532
  htrA Streptococcus pneumoniae Rx1

53.234

100

0.532

Multiple sequence alignment